Potassium disorder Potassium metabolism Hypokalemia • Serum (K+) arms), cramp, numbness, rhabdomyolysis +Cardiac contruction abnormalities : ECG changes, arrthymias ECG changes include • • • • ST depressions T wave inversion Prominent U waves PR, QT prolongation • Dangerous arrthymias are most common when hypokalemia is combined with: QT prolonging drugs Digoxin toxicity Hypomagnesemia Coronary ischema Etiologies by mechanism Etiologies by mechanism Poor Intake GI Losses Urinary Losses + Starvation + Vomitting/ NG drainage + Diuretics + Anorexia +Diarrhea +Mineralocorticoid excess +Laxative abuse +Ureterosigmoidostomy Internal Redistribution Etiologies of Mineralocoticoid excess Etiologies Primary Hyperaldosteronism Secondary Hyperaldosteronism Renin Aldosterone Treatment - Serum potassium levels High risk comorbidities : arrhythmias Serum potassium levels (-) 2,5 – 3,5 [...]... Serum potassium levels High risk comorbidities : arrhythmias Serum potassium levels (-) 2,5 – 3,5 ... 10mmol each hour + ECG, potassium blood test to adjust the dose + ECG, potassium blood test to adjust the dose each hours Arrhythmias (+) + IV KCl : 20 mmol each hour + ECG, potassium blood test... Secondary Hyperaldosteronism Renin Aldosterone Treatment - Serum potassium levels High risk comorbidities : arrhythmias Serum potassium levels (-) 2,5 – 3,5