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Contents
Contributors
Chapter 1: The Established Therapies: HF-PEF and HF-REF
Heart Failure with Reduced Ejection Fraction (HFrEF)
Diuretics
Loop Diuretics
Thiazide and Thiazide-Type Diuretics
Potassium-Sparing Diuretics
ACE-Inhibitors and ARB’s
ACE-Inhibitors
ARB’s
Beta-Blockers
Digoxin
Hydralazine and Isosorbide Dinitrate
Conclusions
Heart Failure with Preserved Ejection Fraction (HFpEF)
Diuretics
ACEI’s and ARB’s
Beta Blockers
Calcium Channel Blockers (CCB)
Aldosterone Antagonists
References
Chapter 2: Novel Therapies for the Prevention and Management of Acute Decompensated Heart Failure
Modulators of Natriuretic Peptides and Renin Angiotensin Aldosterone System (RAAS)
Vasopeptidase Inhibitors
Urodilatin/Ularitide
Vasodilator Therapies
Relaxin
Inotropic Agents
Istaroxime
Levosimendan
Omecamtiv Mecarbil
Adjunctive Therapies
Tolvaptan
References
Chapter 3: A Comprehensive Transition of Care Plan for a Patient Admitted with Acute Decompensated Heart Failure
Introduction
The Scope of the Problem
Are Readmissions Truly the Fault of the Hospital or Physician?
Steps That May Lessen Re-admission
Heart Failure Disease Management
How Can We Target the Development of Heart Failure?
Effectively Treating Congestive Heart Failure, a Brief Overview for the Transition Phase
After Medical Treatment Is the Transition Complete?
Work to End the Cycle of Heart Failure as Part of the Transition
Evaluations That Must Be Accomplished as an Inpatient or Ordered for the Transition to Outpatient Care
Methods to Determine the Prognosis of Patients with ADHF
Determing the Prognosis of Patients Admitted with ADHF
Defining Congestion in Heart Failure
Clinical Scores Consistent with Invasively Obtained Risk Models: The Prognosis Determined Should Impact Therapeutic Decisions in the Transition to Outpatient Care
Non-invasive Risk Scores That Help in the Transition of Care by Assiting the Physician in Determining Prognosis
The Role of Biomarkers in the Transition of Care and in Predicting Prognosis
How to Determine Who to Send for Advanced Options During the Transition of Care Phase
Initiating a Palliative Care Discussion: An Important Step in the Transition to Outpatient Care
Hospice Care for CHF Patients
Heart Failure Management Programs and the Transition of Care
Monitoring Options to Consider as Part of a Heart Failure Disease Management Plan
Conclusion
References
Chapter 4: Volume Assessment and Management: Medical and Device Therapies