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Chromium toxicity and bioaccumulation by chromium tolerant bacillus and arthrobacter species 1

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Chapter I: Introduction CHAPTER I INTRODUCTION 1.1 Background: Heavy metals may be classified as essential and non-essential metals. Heavy metals such as zinc and copper are essential metals as they serve biological functions. Indeed essential metals have been very well studied, for example in their role as enzymatic cofactors or as a part of metalloenzymes. However, the biochemical mechanisms involved in homeostasis, metal metabolism and regulation are still not fully understood. Some of these metals, e.g. copper, nickel and zinc, are essential at low concentrations for the normal functioning of living organisms, but are toxic at high concentrations. Other heavy metals, such as lead, mercury and cadmium, do not serve any known biological function and hence termed as non-essential and can be very harmful to the organism, including human, even at low concentrations. Heavy metals are elements and hence cannot be degraded or destroyed. They tend to be accumulated in soils, plants and animals, with increasing concentrations in the top predators of the food chains. The effect of these heavy metals on human health include different types of cancer, renal dysfunction, alteration of the nervous system, decrease of learning capacity, etc. The effect of heavy metals on the environment depends on their concentration and mobility within the atmosphere, hydrosphere and lithosphere. The polluting heavy metals may be mobilized and transported in solubilized form through air. This includes solid phase (particles and aerosols), liquid (fogs) and gaseous (steams) transfer. Dispersion and dilution lead to contamination of new regions, thus affecting the environment in areas far away from the original pollution. Over the 1 Chapter I: Introduction years, there has been significant increase in the utilization and release of chemicals including heavy metals, due to rapid industrialization and population increase. Industries such as metallurgical, electroplating, metal finishing, tanneries, chemical manufacturing, mine drainage and battery manufacturing are the main sources of heavy metal pollution. Heavy metals, due to their high toxicity, pose a serious threat to biota and environment. In many parts of the world, strict regulations exist that regulate the concentration of metals discharged in the effluent. Conventional techniques for removing dissolved heavy metals include chemical precipitation, chemical reduction, carbon adsorption (Namasivayam and Yamuna, 1995; Lotfi and Adhoum, 2002; Bai and Abraham, 2003), ion exchange (Sengupta and Clifford,1986; Rengaraj et al., 2003), solvent extraction (Mauri et al., 2001), reverse osmosis (Padilla and Tavani, 1999), filtration, membrane process, evaporation and several other electrolytic and chemical methods. However, these techniques are ineffective when applied to low strength waste with heavy metal ion concentration and have certain disadvantages as listed below: There is production and accumulation of secondary waste products during the series of treatments involved in treating heavy metals (including Cr (VI), Cu sludge). Some of the treatment methods involve high operating and maintenance cost (Tewari et al., 2005) There is low efficiency and operational complexity. These methods involve high energy requirements and often incomplete metal removal (Ucun et al., 2002) 2 Chapter I: Introduction Phytoremediation i.e. the use of plants for the treatment of heavy metal contamination is a cost effective method but is considered extremely time consuming. Due to the disadvantages of these methods, there is need for other methodologies that would be efficient at low concentration of pollutants. The use of sorbents of biological origin (Bailey et al., 1999; Babel and Kurniawan, 2003) for the removal of heavy metals has gained interest among researchers due to its several valuable advantages. The biological methods are generally cost effective and biodegrades/detoxify the hazardous contaminants. There is also a possibility of recovery of the metal in the case of biological origin remediation methods. 1.2 Objectives and Scope of the project: The project aims at the following objectives: Isolation of chromium-tolerant microorganism from effluent as well as solid waste from the electroplating industry. Basic biochemical characterization and genus identification of the obtained isolates. A study on the toxicity effects of chromium on these isolates. Indentifying the morphological and biochemical changes of isolates that occur upon exposure to chromium. Determining the chromium binding sites over the functional groups of the microorganisms. Indentifying the behavior of the cells after intracellular transport of chromium. 3 Chapter I: Introduction Surface morphological changes after chromium bioaccumulation and its quantification. 4 ... (Namasivayam and Yamuna, 19 95; Lotfi and Adhoum, 2002; Bai and Abraham, 2003), ion exchange (Sengupta and Clifford ,19 86; Rengaraj et al., 2003), solvent extraction (Mauri et al., 20 01) , reverse... study on the toxicity effects of chromium on these isolates Indentifying the morphological and biochemical changes of isolates that occur upon exposure to chromium Determining the chromium binding... extraction (Mauri et al., 20 01) , reverse osmosis (Padilla and Tavani, 19 99), filtration, membrane process, evaporation and several other electrolytic and chemical methods However, these techniques are

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