15. giáo trình COPD tiếng anh

Chronic Obstructive Pulmonary Disease DEFINITION OF COPD Normal COPD  Chronic Obstructive Pulmonary Disease (COPD) is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases  COPD is preventable and treatable. The patients with COPD have comorbidities DEFINITION OF COPD Mortality of COPD in The World Trevor Hansel, Peter Barne (2004) THE RICK FACTORS OF COPD Environmental factors  Cigarette smoking  Exposures to indoor and outdoor air pollutants  Occupational exposures  Respiratory infections  Socioeconomic Status Local factor  Genetic  Airway hyperresponsiveness  Age  Gender The inflammation in the lung Oxidative stress Proteinases Tissue reconstruction Anti-proteinases Anti-oxidants Local factors Exposure to Particles Pathogenesis of COPD Pathology of COPD Nguồn : Peter J. Barnes, MD Hypoxic Vasoconstriction of small pulmonary arteries • Smooth muscle hypertrophy • Intimal hyperplasia • Fibrosis • Embolism Pulmonary hypertension Right-side cardiac failure Mortality Edema Pulmonary Hypertension in copd Peter J. Barnes, MD Clinical Course of COPD Air Trapping Expiratory Flow Limitation Breathlessness Inactivity Poor Health-Related Quality of Life Hyperinflation Deconditioning COPD Disability Disease progression Death Reduced Exercise Capacity COPD Exacerbations 1. Chronic bronchitis 2. Obstructive bronchiolitis 3. Emphysema 4. Pulmonary vascular disease 5. Systemic Features Pathology 1. Chronic bronchitis Dyspnea, chronic cough or sputum production Pathology Exertional dyspnea Acute dyspnea ( FEV1 < 50%) Pathology 2. Obtructive bronchiolitis [...]... Spirometry Spirometry Lửu lửụùng Lửu lửụùng ủổnh V50 Bỡnh thửụứng V25 COPD Theồ tớch COPD tieỏn trieồn Diagnosis of COPD Symptoms Cough Sputumproduction Dyspnea Exposure to risk factors: Tobacco smokeÔ Smoke from home cooking and heating fuels Occupational dusts andchemicals Spirometry - postbronchodilator FEV1/FVC . gases  COPD is preventable and treatable. The patients with COPD have comorbidities DEFINITION OF COPD Mortality of COPD in The World Trevor Hansel, Peter Barne (2004) THE RICK FACTORS OF COPD Environmental. Chronic Obstructive Pulmonary Disease DEFINITION OF COPD Normal COPD  Chronic Obstructive Pulmonary Disease (COPD) is characterized by persistent airflow limitation that is usually. Hypertension in copd Peter J. Barnes, MD Clinical Course of COPD Air Trapping Expiratory Flow Limitation Breathlessness Inactivity Poor Health-Related Quality of Life Hyperinflation Deconditioning COPD Disability