Nanotechnology kỹ thuật nano

NANOTECHNOLOGY- BASICS AND ITS APPLICATION IN MEDICINE Keith ó Proinsias What is Nanotechnology? What is Nanotechnology? • Nanoscience: involves research and technology development at 1nm to 100nm range (nanoscale) • Nanotechnology creates and uses structures that have novel properties because of their small size • Nanotechnology builds on the ability to control or manipulate at atomic scale What is Nanotechnology? History The word “Nanotechnology” is new, its existance has been around for a long time History • Abalone • Mollusk • Strong shell, consisting of organised calcium carbonate into strong nanostructured bricks History • 29 th December , 1959 • At the annual meeting of the American Physical Society at California Institute of Technology “There’s plenty of room at the bottom” • Richard P. Feynman • Known as the “father of nanotechology” Why Nanotechnology? Applications • Medical • Bio-materials • Drug delivery • Energy and industrial • Solar / Fuel Cells • Lighting • Coating and powders • Paint • Textiles • Devices and microelectronics • Sensors • Microprocessors / memory and storage Outline Nanoparticles Quantum dots Nanotubes Fabrication [...]... electrode form nanotubes on the negative electrode • Chemical vapor deposition: decomposition of hydrocarbon gas (CH4) at 110oC Nanomedicine Nanomedicine Nanomedicine: is the medical application of nanotechnology Nanoshells Nanogels Nanorobotics Nanomedicine Advantages: • Suitable for encapsulation • Release drugs in a controlled manner • More efficient uptake of cells ... through direct and indirect mediation • Applied in light harvesting Nano lett., 2002, 2, 965-968 Carbon Nanotubes • Sheets of graphite rolled into a tube • Single walled nanotubes (SWNT) can have a diameter of 2nm and a length of 100µm • There are different types of carbon nanotube structures, a) armchair b) zigzag c) chiral Carbon Nanotubes • Applications: • Field Emissions • Conductive plastics •... Carbon Nanotubes and Porphyrins • Prepared carbon nanotubes linked to Zn-porphyrins via the click reaction • Applied in light harvesting J Am Chem Soc., 2009, 131, 15394-15402 • Covalently bonded porphyrins to carbon nanotubes • Construct novel photovoltaic devices and light-harvesting systems J Am Chem Soc., 2005, 127, 6916-6917 Fabrication at nano scale Two approaches to fabricating at nano scale,...Nanoparticles • A nanoparticle is a microscopic particle with at least one dimension less than 100nm • Nanoparticles are of great scientific interest as they are effectively a bridge between bulk materials and atomic or molecular structures • Gold nanoparticles exhibit vast medical/health advantages www.sciencedaily.com/articles/n/nanoparticle.htm Quantum Dots • Semiconducting... Nanotubes • Three methods: • Laser evaporation: within a quartz tube containing argon gas and the graphite target, its heated to 1200oC • Carbon arc: a potential is applied across two carbon electrodes under 500 torr of pressure Carbon atom from the positive electrode form nanotubes on the negative electrode • Chemical vapor deposition: decomposition of hydrocarbon gas (CH4) at 110oC Nanomedicine Nanomedicine... systems J Am Chem Soc., 2005, 127, 6916-6917 Fabrication at nano scale Two approaches to fabricating at nano scale, 1 Top Down 2 Bottom Up Nano Scale Fabrication: Top Down • • • • Similar to a sculptor cutting away at a block of mable Begins at large scale and ends with a nano scaled product Used in the computer industry in creating microprocessors Utilizes a techniques such as, • Colloidal synthesis • Epitoxy... coated with radiation-sensitive resist • The resist material usually consists of polymer polymethyl methacrylate • The resist is then removed • The surface is chemically treated to produce the nanostructure Nano Scale Fabrication: Bottom Down • Employs “self-assembly” process • Under specific conditions the atoms and molecules arrange themselves into the product Self Assembly • • • Originated from . NANOTECHNOLOGY- BASICS AND ITS APPLICATION IN MEDICINE Keith ó Proinsias What is Nanotechnology? What is Nanotechnology? • Nanoscience: involves research. (nanoscale) • Nanotechnology creates and uses structures that have novel properties because of their small size • Nanotechnology builds on the ability to control or manipulate at atomic scale What is Nanotechnology? History The. the ability to control or manipulate at atomic scale What is Nanotechnology? History The word Nanotechnology is new, its existance has been around for a long time History • Abalone • Mollusk •