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[...]... arrhythmias Glucocorticoids Methylprednisolone (0.4–0.8 mg/kg) is the preferred agent for the control of erythema and pruritus Prednisolone and prednisone may also be used (0.5–1.0 mg/kg), but they are more likely to cause polyuria/polydipsia and polyphagia in some dogs Induction doses should be given twice daily for 8 days or until remission, then once daily in the morning for 8 days, and then on alternate mornings... are small, solid, elevated lesions up to 1 cm (0.4 in) in diameter associated with cell infiltration and/or proliferation, in this case a mast cell tumor A plaque is a flat, solid, elevated lesion of more than 1 cm (0.4 in) in diameter, again associated with cell infiltration and/or proliferation The lesions illustrated are eosinophilic plaques on a cat Introduction 11 A nodule is a solid elevation of... lotions containing 1% hydrocortisone twice daily Areas of severe inflammation and lichenification can be treated with betamethasone valerate cream 0.1% twice daily This cream is especially beneficial in treating erythema and pruritus of the web skin between the toes and the skin under the tail and around the rectum Betamethasone valerate is a potent steroid and systemic absorption can occur, causing adrenocortical... products or prednisone (0.5–1.0 mg/kg p/o q24h for 3–5 days) or methylprednisolone (0.4–0.8 mg/kg p/o q24h for 3–5 days) are very effective when used at the owners’ discretion to control short-term exacerbation in dogs otherwise controlled on non-steroidal therapy or during food trials Adverse effects are rarely seen with this protocol Methylprednisolone acetate (0.25–1.0 mg/ kg i/m) or betamethasone (0.08–0.4... signs of skin disease CAFRs can also cause gastrointestinal tract (GIT) signs including soft feces, flatulence, intermittent diarrhea, and colitis In one study, 60% of dogs also had some form of GIT signs, usually manifested by an increased number of bowel movements (greater than or equal to six per day)10 It has also been reported to trigger recurrent pyoderma12 and nail disorders13 Pruritus, crusting,... treated with a drying solution of 2% aluminum acetate (Domeboro solution) for 3–5 minutes to decrease exudation After cleaning and drying, an antibiotic–steroid cream or ointment can be applied Application of the drying solution and antibiotic–corticosteroid preparation can be continued at home by the owner 2–3 times a day A novel, topical diester glucocorticoid spray (hydrocortisone aceponate) is highly... Clients should also be instructed to wear gloves when betamethasone valerate is applied, as it can cause a thinning of the skin with continued contact Triamcinolone spray 0.015% applied twice daily may be very beneficial for treating focal areas as well as larger areas of inflammation A topical spray formulation of the diester glucocorticoid hydrocortisone aceponate has recently become available Diester... recurrence in most animals, but some that are very prone to repeated infection will benefit from an alternative to constant antibacterial treatment In these cases the animal is given the standard dose of an antibacterial (e.g cefalexin or dicloxacillin) twice daily on 2–3 consecutive days per week (e.g ‘weekend therapy’) after initial resolution of the infection with standard dosing An alternative to... minimal adverse effects when applied once daily If the lesion is extensive or severe, systemic corticosteroids at antiinflammatory doses can be used for 3–7 days, or as necessary, to reduce the inflammation and shorten the time necessary for resolution of the lesion Most lesions resolve in 3–7 days, but they may recur if predisposing factors are not corrected Some individuals of certain breeds, particularly... short-acting steroids such as prednisone, prednisolone, and methylprednisolone should be discontinued three weeks prior to testing, and repository injectable steroids should be discontinued 6–8 weeks prior to testing Antihistamines should be discontinued 7–10 days before testing Control of pruritus pending testing may be achieved by bathing the animal every 1–3 days using emollient moisturizing shampoos, . Synotic hydrocortisone aceponate Cortavance imiquimod cream Aldara isotretinoin Accutane mitotane (o,p’-DDD) Lysodren moxidectin/imidacloprid Advocate parachlorometaxylenol (PCMX) Epi-Otic Advanced pentoxifylline. DipECVD, MRCVS Godiva Referrals, Coventry, UK Patrick J. McKeever DVM, MS, DACVD Professor Emeritus McKeever Dermatology Clinics, Eden Prairie, Minnesota, USA A Colour Handbook of MANSON PUBLISHING/THE. are small, solid, elevated lesions up to 1 cm (0.4 in) in diameter associated with cell infiltration and/or proliferation, in this case a mast cell tumor. A plaque is a flat, solid, elevated lesion

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