Báo cáo TYPES OF STEM CELL

TYPES OF STEM CELL GROUP 10 Outline Introduction Introduction of stem cell Presenter: Pham Quynh Hoa What are stem cells? • Stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide (through mitosis) to produce more stem cells Stem cell potency Stem cell properties Different types of stem cell Embryonic stem cells Presenter: Bach Thi Hoai Phuong Different kinds of stem cells • Embryonic stem cells (ES): the cells of the inner cell mass blastomeres when cultured, which remain pluripotent. • Pluripotent stem cells are generated from germ cells derived from spontaneously aborted fetuses (bào thai không phát triển): embryonic germ (EG) cells. [...]... men’s cells could give rise to germ cells at all was a surprise Adult stem cells Presenter: Trinh Thi Thu Hien Adult stem cells Adult stem cells (ASCs)  undifferentiated  found throughout the body after development  multiply by cells division to replenish dying cells and regenerate damaged tissue Adult stem cells reside in a specific area of each tissue called a stem cell niche” Adult stem cells... characteristic of induced pluripotent stem cells • Induced pluripotent stem cells or IPSCs are a type of pluripotent stem cells that can be generated directly from adult cells • IPSCs can be able seft-renewing and pluripotent • The most well-known type of pluripotent stem cell is the embryonic stem cell • They can give rise to other cell type in the body of the patient such as neurons, liver cells, and... Mesenchymal stem cells (multipotent stromal cells) Osteocytes (bone cells) Chondrocytes (cartilage cells) Adipocytes (fat cells) Connective tissues Neural stem cells (in the brain) Neurons, astrocytes and oligodendrocytes Types of ASCs – Normal differentiation pathways http://stemcells.nih.gov/info/basics/pages/basics4.aspx Types of ASCs Plasticity/ Transdifferentiation • Differentiate into cell types in... associated with immune rejection Adult stem cells Adult stem cells produce some daughter cells (Asymmetrical division) differentiated remain stem cells Regulate the proliferation and differentiation by paracrine factors Cells that leave the niche paracrine factors cannot reach them cells and begin differentiating Adult stem cells Asymmectrical division of stem cell niche Drosophila testes Scott F Gilbert,... from the cells predicted lineage (i.e: brain stem cells differentiate into blood cells or blood-forming cells differentiate into cardiac muscle cells ) • Reprogrammed Types of ASCsPlasticity/ Transdifferentiation Reprogrammed: • β-cells (pancreas gland) that release insulin are lost or damaged in diabetes • Re-starting β -cell genes by creating β -cell- like cells (reprogramming other pancreatic cells –... testes Scott F Gilbert, Developmental Biology 9th Edition Types of ASCs - Differentiation pathway • Normal differentiation pathways: give rise to mature cell types that have functions of a particular tissue • Plasticity (Transdifferentiation) Types of ASCs – Normal differentiation pathways Hematopoietic stem cells All types of blood cells (red blood cells, B lymphocytes, T lymphocytes, neutrophil, basophils,... exocrine cells) What tests are used for identifying adult stem cells 1 Label the cells in a living tissue with molecular markers and determine the specialized cell types they generate 2 Remove the cell from a living animal, label them in cell culture, and transplant them back to another animal to determine whether the cells replace ( or “repopulate”) their tissue of origin Induced pluripotent stem cells... Adult stem cells Embryonic stem cells can become all cell types of the body because they are pluripotent • can be grown relatively easily in culture Adult stem cells • are thought to be limited to differentiating into different cell types of their tissue of origin rare in mature tissues, difficult to isolate and culture • • • be obtained from the other person, thereby these cells are “strange” with the... Infertile men cure Renee Reijo Pera Stem cells from some infertile men form germ cells when transplanted into mice, study finds (http://med.stanford.edu/ism/2014/may/germcell.html#sthash.A1fdKLFR.dpuf) • • • • • Stem cells made from the skin of adult, infertile men yield primordial germ cells — cells that normally become sperm — when transplanted into the reproductive system of mice, according to researchers... primordial germ cells from the infertile men, their stem cells made far fewer of these sperm progenitors than did stem cells from men without the mutations The research provides a useful, much-needed model to study the earliest steps of human reproduction The research used skin samples from five men to create what are known as induced pluripotent stem cells, which closely resemble embryonic stem cells in . into specialized cells and can divide (through mitosis) to produce more stem cells Stem cell potency Stem cell properties Different types of stem cell Embryonic stem cells Presenter: Bach. TYPES OF STEM CELL GROUP 10 Outline Introduction Introduction of stem cell Presenter: Pham Quynh Hoa What are stem cells? • Stem cells are undifferentiated biological cells that. replenish dying cells and regenerate damaged tissue Adult stem cells reside in a specific area of each tissue called a stem cell niche”. Adult stem cells Embryonic stem cells Adult stem cells •