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Genetics of AMD 491 [...]... neovascularization caused by age-related macular degeneration: results of a single treatment in a phase 1 and 2 study Arch Ophthalmol 1999;117:1161–1173 9 Finger PT, Chakravarthy U, Augsburger JJ Radiotherapy and the treatment of age-related macular degeneration External beam radiation therapy is effective in the treatment of age-related macular degeneration Arch Ophthalmol 1998;116:1507–1511 10 Bergink GJ, Hoyng... macular degeneration Am J Ophthalmol 1988 ;105 :25–9 36 Roth DB, Downie AA, Charles ST Visual results after submacular surgery for neovascularization in age-related macular degeneration Opthalm Surg Lasers 1997;28:920–925 37 Merrill PT, LoRusso FJ, Lomeo MD, Saxe SJ, Khan MM, Lambert HM Surgical removal of subfoveal choroidal neovascularization in age-related macular degeneration Ophthalmology 1999 ;106 :782–789... photocoagulation of subfoveal neovascular lesions in age-related macular degeneration Results of a randomized clinical trial Arch Ophthalmol 1991 ;109 :1220–1231 6 Macular Photocoagulation Study Group Laser photocoagulation of subfoveal recurrent neovascular lesions in age-related macular degeneration results of a randomized clinical trial Arch Ophthalmol 1991 ;109 :1232–1241 7 TAP Study Group Photodynamic therapy... Schachat AP, Hartranft CD Limited inferior macular translocation for the treatment of subfoveal choroidal neovascularization secondary to age-related macular degeneration Am J Ophthalmol 2000;130:419–428 16 Donahue SP, Wall M, Weingeist TA Interferon treatment of SRNV Ophthalmology 1994 ;101 :624–625 17 Fung WE Interferon alpha 2a for treatment of age-related macular degeneration Am J Ophthalmol 1991;112:349–350... TAP Study Group Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: one-year results of 2 randomized clinical trials— TAP report Treatment of age-related macular degeneration with photodynamic therapy Arch Ophthalmol 1999;117:1329–1345 8 Miller JW, Schmidt-Erfurth U, Sickenberg M, Pournaras CJ, Laqua H, Barbazetto I, Zorafos L, Piguet... patients’ perceptions of quality of life associated with age-related macular degeneration Can J Ophthalmol 2000;35:127–133 7 Ware JE Jr, Sherbourne CD The MOS 36-item short-form health survey (SF-36), I Conceptual framework and item selection Med Care 1992;30:473–483 8 McHorney CA, Ware JE Jr, Raczek AE The MOS 36-item short-form health survey (SF-36), II: psychometric and clinical tests of validity in... The synthetic tetrapeptide RGDS (arginineglycine-aspartate-serine), which is derived from the cell-binding domain of fibronectin, decreases RPE binding to laminin-coated or fibronectin-coated dishes (66) When added simultaneously with the cells, binding of RPE to fibronectin-coated dishes and laminin-coated dishes can be blocked by an antibody to the ␤1-subunit of integrin but RPE cell binding to charged... membranes in age-related macular degeneration Br J Ophthalmol 1997;81:481–489 41 Pollack JS, Del Priore LV, Smith ME, Feiner MA, Kaplan HJ Postoperative abnormalities of the choriocapillaris in exudative age-related macular degeneration Br J Ophthalmol 1996;80:314–8 42 Akduman L, Desai V, Del Priore LV, Olk PJ, Kaplan HJ Perfusion of the subfoveal choriocapillaris affects visual recovery after submacular... description of the subscales of the SF-36 As a comprehensive QOL instrument, the SF-36 has often been used to complement vision-specific instruments, as discussed below (10 12) In these studies, correlations between the vision-specific instruments and the SF-36 subscales have usually been fairly low Table 1 Description of the Subscales of the Short-Form 36 (SF-36) SF-36 subscale Description Physical health... vision-related function in patients with age-related macular degeneration Ophthalmology In press The VF-14 was correlated with the SF-36 physical composite scale (PCS) but not with the mental composite scale (MCS) This may indicate that one limitation of the VF14 is that it does not assess the mental aspects of health-related QOL in patients with AMD Indeed, focus groups used to develop the NEI-VFQ . associated with age-related macular degeneration. Arch Ophthalmol 2001;119(5):745–751. 107 . Allikmets R. Further evidence for an association of ABCR alleles with age-related macular degeneration. . (arginine- glycine-aspartate-serine), which is derived from the cell-binding domain of fibronectin, de- creases RPE binding to laminin-coated or fibronectin-coated dishes (66). When added si- multaneously. treatment of age-related mac- ular degeneration. External beam radiation therapy is effective in the treatment of age-related macular degeneration. Arch Ophthalmol 1998;116:1507–1511. 10. Bergink

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