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Chapter 103. Polycythemia Vera and Other Myeloproliferative Diseases (Part 7) pdf

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Chapter 103. Polycythemia Vera and Other Myeloproliferative Diseases (Part 7) Table 103-4 Risk Stratification for Idiopathic Myelofibrosis A. Prognostic factors a Hemoglobin <10 gm% White cell count < 4000/µL or > 30,000/µL Number of prognostic factors Risk group Median survival (months) 0 Low 93 1–2 High 17 B. Prognostic factors b Hemoglobin < 10 gm% Constitutional symptoms Blast cells > 1% Number of prognostic factors Risk group Median survival (months) 0–1 Low 99 2–3 High 21 C. Prognostic factors c Median survival (months) Age <65 years Hemoglobin ≤10 gm% Karyotype: Normal 54 Abnormal 22 Age <65 years Hemoglobin >10 gm% Karyotype: Normal 180 Abnormal 72 Age >65 years Hemoglobin ≤10 gm% Karyotype: Normal 44 Abnormal 16 Age >65 years Hemoglobin >10 gm% Karyotype: Normal 70 Abnormal 78 a From B Dupriez et al. Blood 88:1013, 1996. b From F Cervantes et al. Br J Haematol 102:684, 1998. c From JT Reilly et al. Br J Haematol 98:96, 1997. . Chapter 103. Polycythemia Vera and Other Myeloproliferative Diseases (Part 7) Table 103- 4 Risk Stratification for Idiopathic Myelofibrosis

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