Chapter 030. Disorders of Smell, Taste, and Hearing (Part 6) Approach to the Patient: Disorders of the Sense of Taste Patients who complain of loss of taste should be evaluated for both gustatory and olfactory function. Clinical assessment of taste is not as well developed or standardized as that of smell. The first step is to perform suprathreshold whole-mouth taste testing for quality, intensity, and pleasantness perception of four taste qualities: sweet, salty, sour, and bitter. Most commonly used reagents for taste testing are sucrose, citric acid or hydrochloric acid, caffeine or quinine (sulfate or hydrochloride), and sodium chloride. The taste stimuli should be freshly prepared and have similar viscosity. For quantification, detection thresholds are obtained by applying graduated dilutions to the tongue quadrants or by whole-mouth sips. Electric taste testing (electrogustometry) is used clinically to identify taste deficits in specific quadrants of the tongue. Regional gustatory testing may also be performed to assess for the possibility of loss localized to one or several receptor fields as a result of a peripheral or central lesion. The history of the disease and localization studies provide important clues to the causes of the taste disturbance. For example, absence of taste on the anterior two-thirds of the tongue associated with a facial paralysis indicates that the lesion is proximal to the juncture of the chorda tympani branch with the facial nerve in the mastoid. Disorders of the Sense of Taste: Treatment Treatment of gustatory disorders is limited. No effective therapies exist for the sensorineural disorders of taste. Altered taste due to surgical stretch injury of the chorda tympani nerve usually improves within 3–4 months, while dysfunction is usually permanent with transection of the nerve. Taste dysfunction following trauma may resolve spontaneously without intervention and is more likely to do so than posttraumatic smell dysfunction. Idiopathic alterations of taste sensitivity usually remain stable or worsen; zinc and vitamin therapy are of unproven value. Directed therapy to address factors that affect taste perception can be of value. Xerostomia can be treated with artificial saliva, providing some benefit to patients with a disturbed salivary milieu. Oral pilocarpine may be beneficial for a variety of forms of xerostomia. Appropriate treatment of bacterial and fungal infections of the oral cavity can be of great help in improving taste function. Taste disturbance related to drugs can often be resolved by changing the prescribed medication. Hearing Hearing loss is one of the most common sensory disorders in humans and can present at any age. Nearly 10% of the adult population has some hearing loss, and one-third of individuals >65 years have a hearing loss of sufficient magnitude to require a hearing aid. Physiology of Hearing (Fig. 30-3) The function of the external and middle ear is to amplify sound to facilitate mechanotransduction by hair cells in the inner ear. Sound waves enter the external auditory canal and set the tympanic membrane in motion, which in turn moves the malleus, incus, and stapes of the middle ear. Movement of the footplate of the stapes causes pressure changes in the fluid-filled inner ear eliciting a traveling wave in the basilar membrane of the cochlea. The tympanic membrane and the ossicular chain in the middle ear serve as an impedance-matching mechanism, improving the efficiency of energy transfer from air to the fluid-filled inner ear. Figure 30-3 . Chapter 030. Disorders of Smell, Taste, and Hearing (Part 6) Approach to the Patient: Disorders of the Sense of Taste Patients who complain of loss of taste should be. medication. Hearing Hearing loss is one of the most common sensory disorders in humans and can present at any age. Nearly 10% of the adult population has some hearing loss, and one-third of individuals. individuals >65 years have a hearing loss of sufficient magnitude to require a hearing aid. Physiology of Hearing (Fig. 30-3) The function of the external and middle ear is to amplify sound