Chapter 022. Dizziness and Vertigo (Part 1) doc

Chapter 022. Dizziness and Vertigo (Part 1) Harrison's Internal Medicine > Chapter 22. Dizziness and Vertigo Dizziness and Vertigo: Introduction Dizziness is a common and often vexing symptom. Patients use the term to encompass a variety of sensations, including those that seem semantically appropriate (e.g., lightheadedness, faintness, spinning, giddiness) and those that are misleadingly inappropriate, such as mental confusion, blurred vision, headache, or tingling. Moreover, some individuals with gait disorders caused by peripheral neuropathy, myelopathy, spasticity, parkinsonism, or cerebellar ataxia complain of "dizziness" despite the absence of vertigo or other abnormal cephalic sensations. In this context, the term dizziness is being used to describe disturbed ambulation. There may be mild associated lightheadedness, particularly with impaired sensation from the feet or poor vision; this is known as multiple-sensory-defect dizziness and occurs in elderly individuals who complain of dizziness only when walking. Decreased position sense (secondary to neuropathy or myelopathy) and poor vision (from cataracts or retinal degeneration) create an overreliance on the aging vestibular apparatus. A less precise but sometimes comforting designation to patients is benign dysequilibrium of aging. Thus, a careful history is necessary to determine exactly what a patient who states, "Doctor, I'm dizzy," is experiencing. After eliminating the misleading symptoms or gait disturbance, "dizziness" usually means either faintness (presyncope) or vertigo (an illusory or hallucinatory sense of movement of the body or environment, most often a feeling of spinning). Operationally, after obtaining the history, dizziness may be classified into three categories: (1) faintness, (2) vertigo, and (3) miscellaneous head sensations. Faintness Prior to an actual faint (syncope), there are often prodromal presyncopal symptoms (faintness) reflecting ischemia to a degree insufficient to impair consciousness. These include lightheadedness, "dizziness" without true vertigo, a feeling of warmth, diaphoresis, nausea, and visual blurring occasionally proceeding to blindness. Presyncopal symptoms vary in duration and may increase in severity until loss of consciousness occurs or may resolve prior to loss of consciousness if the cerebral ischemia is corrected. Faintness and syncope are discussed in detail in Chap. 21. Vertigo Vertigo is usually due to a disturbance in the vestibular system. The end organs of this system, situated in the bony labyrinths of the inner ears, consist of the three semicircular canals and the otolithic apparatus (utricle and saccule) on each side. The canals transduce angular acceleration, while the otoliths transduce linear acceleration and the static gravitational forces that provide a sense of head position in space. The neural output of the end organs is conveyed to the vestibular nuclei in the brainstem via the eighth cranial nerves. The principal projections from the vestibular nuclei are to the nuclei of cranial nerves III, IV, and VI; spinal cord; cerebral cortex; and cerebellum. The vestibuloocular reflex (VOR) serves to maintain visual stability during head movement and depends on direct projections from the vestibular nuclei to the sixth cranial nerve (abducens) nuclei in the pons and, via the medial longitudinal fasciculus, to the third (oculomotor) and fourth (trochlear) cranial nerve nuclei in the midbrain. These connections account for the nystagmus (to-and-fro oscillation of the eyes) that is an almost invariable accompaniment of vestibular dysfunction. The vestibular nerves and nuclei project to areas of the cerebellum (primarily the flocculus and nodulus) that modulate the VOR. The vestibulospinal pathways assist in the maintenance of postural stability. Projections to the cerebral cortex, via the thalamus, provide conscious awareness of head position and movement. The vestibular system is one of three sensory systems subserving spatial orientation and posture; the other two are the visual system (retina to occipital cortex) and the somatosensory system that conveys peripheral information from skin, joint, and muscle receptors. The three stabilizing systems overlap sufficiently to compensate (partially or completely) for each other's deficiencies. Vertigo may represent either physiologic stimulation or pathologic dysfunction in any of the three sensory systems. . Chapter 022. Dizziness and Vertigo (Part 1) Harrison's Internal Medicine > Chapter 22. Dizziness and Vertigo Dizziness and Vertigo: Introduction Dizziness is a common and often. multiple-sensory-defect dizziness and occurs in elderly individuals who complain of dizziness only when walking. Decreased position sense (secondary to neuropathy or myelopathy) and poor vision (from. spinning). Operationally, after obtaining the history, dizziness may be classified into three categories: (1) faintness, (2) vertigo, and (3) miscellaneous head sensations. Faintness Prior