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[...]... Several new topics have been added, including: safety aspects of magnetic fields; fetal magnetography; new MRI techniques for cardiovascular imaging; clinical applications at ultra-high fields; interventional magnetic resonance imaging; concepts, systems, applications and new approaches in diagnostic and therapeutic MR mammography; monitoring of magnetic markers; remote-controlled drug delivery; and magnetic... electron beam tomography (EBT) In other cases – for example, that of nuclear magnetic resonance – the time taken between its discovery and subsequent application in medicine was longer Sometimes, a new method has become established in clinical practice only after having passed through a long period of in- vitro investigations and preclinical trials However, there are applications – for example, in biomagnetism... Hildanus (1560–1634), a German physician who practiced medicine in Bern, Switzerland, documented the first case of an iron splinter being extracted from a patient’s eye chamber The following is a translation of the physician’s original Latin description, titled ‘‘Of a slag splinter stuck in the cornea and its ingenious healing’’ (Hildanus, 1627): ‘ A certain farmer from the valley St Michelis, as they... Metabolic Information and Clinical Application: In- Vivo 13 C MRS Metabolic Information and Clinical Application: In- Vivo 19 F MRS Metabolic Information and Clinical Application: In- Vivo 31 P MRS Application of MRS in Diagnostics and Clinical Research: Conclusions and Perspectives 472 References 474 4 Magnetic Substances and Externally Applied Fields 4.1 Introduction 479 ¨ Wilfried Andra References 480 4.2... source imaging (MSI) in recent years is proof enough of the fact that even high-level technologies, which are already in existence, can be essentially improved and expanded as soon as interdisciplinary teams are involved Moreover, there are also topics for which a level of knowledge has not yet been attained that would enable a ‘‘chain reaction’’ to start and thus accelerate further development Here, in. .. disease were thought to benefit from small doses of iron filings mixed with strong vinegar Gilbert found that this mixture also helped older patients with splenomegaly, chronic malaria and anemia – diseases not uncommon in the East Anglian swamps of England at that time More believable accounts of the applications of magnetic forces – at least in terms of present-day standards – began to appear in the... century For example, Andreas Frisii described a case in which a needle accidentally lodged in the side of a person’s throat was removed by a traveling mountebank, as ‘‘ fools rush in where wise men fear to tread’’ (Frisii, 1670): 1.1.3 Use of Attracting Forces of Magnets in Medicine ‘‘When the master permitted the use of water from the spa because of health reasons, a careless maid swallowed a needle... folklore and superstition in his writings He also theorized that ‘‘sympathies and antipathies’’ were the cause of magnetic phenomena, a viewpoint which was shared by Galen of Pergamum (129–199 AD) Galen compared the lodestone to cathartic drugs which attract certain ‘‘qualities’’ such as bile and phlegm, to drugs which remove thorns and arrow-points or draw out animal and arrow-tip poisons, and to ‘‘corn’’,... et al., 1964) or pieces of wire from bales of hay In order to prevent these sharp objects from damaging the stomach and intestinal walls, the cows are forced to swallow a ‘‘cow magnet’’, a 7 cm-long and 1 cm-diameter rod Alnico magnet covered with an anticorrosive plastic coating The cow magnet remains in one of the cow’s stomachs, where it attracts any steel or iron objects that pass by, rendering... Germany Jens Haueisen Institute of Biomedical Engineering and Informatics TU Ilmenau Gustav-Kirchhoff-Strasse 2 98693 Ilmenau Germany Uwe A. O Heinlein Miltenyi Biotec GmbH Friedrich-Ebert-Strasse 68 51429 Bergisch Gladbach Germany Rudolf Hergt ¨ Institut fur Physikalische Hochtechnologie e.V Jena Albert-Einstein-Strasse 9 07745 Jena Germany Karl-Heinz Herrmann Institute of Diagnostic and Interventional . Metabolic Information and Clinical Application: In- Vivo 13 C MRS 469 3.3.7.5 Metabolic Information and Clinical Application: In- Vivo 19 F MRS 469 3.3.7.6 Metabolic Information and Clinical Application:. class="bi x0 y0 w0 h0" alt="" Magnetism in Medicine Edited by Wilfried Andra ¨ and Hannes Nowak