history and trends in bioprocessing and biotransformation - t. scheper, n. n. dutta, f. hammar

[...]... Sperling, Virchow-Klinikum, Berlin A Meindl, LMU, München A Rosenthal, IMB, Jena S Bähring, Franz-Volhard-Klinik, Berlin A Reis, MDC, Berlin F Luft, Franz-Volhard-Klinik, Berlin I Hangman, Halle University R Lilly, Marburg University T Meeting, LMU, Munich H Lehrach, MPI for Molecular Genetics, Berlin R Setback, MPI for Molecular Genetics, Berlin M.-L Yaps, MPI for Molecular Genetics, Berlin 20 F Hammar. .. physical and transcriptional mapping of human chromosome 20q13 segment as candidate for imprinting MITOP – the mitochondria project Molecular analysis of the vertebrate genome H von Melchner, Frankfurt/Main University M Meisterernst, E.-L Winnacker, LMU Munich F Luft, Franz-Volhard-Klinik, Berlin E Reis, MDC, Berlin H Schuster, Franz-Volhard-Klinik, Berlin J Reich, MDC, Berlin K Rohde, MDC, Berlin T Wienker,... DNA-sequence evolution; mutation and variation in the human genome Computer-assisted phylogenetic analysis large genomic regions A comparative map of mouse, rat and Chinese hamster genomes by interspecies chromosome painting; cross-species color segmenting – a novel tool in human karyotype analysis Comparative (Zoo-FISH) genome mapping and positional cloning of evolutionary chromosome breakpoints in. .. market leader in the field of isolation, purification and amplification of nucleic acids By acquiring a manufacturer of liquid-handling instruments, Qiagen has also entered into the production of equipment In addition the company offers services around the purification of DNA on the industrial scale and acts as a partner in several large genome-sequencing projects 4.1.2 Rhein-Biotech – Becoming a Global...10 F Hammar Berlin The close integration between basic and clinical research is aimed at making new scientific findings available for patients as quickly as possible The MDC is a national research foundation It obtains 90% of its funding from the Federal Ministry of Education and Science, with the remaining 10% coming from the state of Berlin 2.2 The German Center for Cancer Research in Heidelberg... Genetics, Berlin 21 History of Modern Genetics in Germany Table 2 (continued) Research topic Group leader/coordinator Systematic functional analysis and mapping of H Jäckle, MPI for Biophysical X-chromosomal genes in Drosophila melanogaster Chemistry, Göttingen Sequencing Sequencing of full-length cDNAs in the course of the German Genome Project Towards sequencing of chromosome 21: sequencing and automated... demonstrated, and there will certainly be further developments towards the critical ability to identify and/ or verify hundreds of proteins per day in the very near future, thus accelerating the search for clinical markers By means of analyzing signal transduction pathways, multi-protein-complexes and the dynamic changes of protein expression, the effects of candidate drugs can be determined, including comprehensive... scientists but essential constituents of every living being including man An informed and predominantly consenting public (the later customers of genetically engineered products!) provides the basis for benefiting from the advantages of molecular biology for plant and food production and to establish a sustainable industry in this area of business 28 F Hammar References 1 2 3 4 5 6 7 8 9 10 11 12 13... characterization of protein-protein interactions in man T Boehm, MPI for Immunobiology, Freiburg A Bindereif, Giessen University Mapping/cytogenetics Central Genotyping Service (GSU) at the Max Delbrück Center Theoretical and experimental analysis of chromatin three-dimensional structure and internal motions Exon map in proximal Yq11 Generation of sequence-ready maps of human chromosome 17p Production and application... fluorescence correlation spectroscopy and related single-molecule detection technologies and develops liquid-handling instrumentation and high-density assay formats for automated miniaturized ultra-high performance screening 4.2 The BioRegio Contest – Gambling for Success Despite the activities of this handful of companies, Germany in the early 1990s was still a wasteland for life science entrepreneurs Oppressive . count on further expansion.The founding of new institutes was History of Modern Genetics in Germany 7 only possible through the renaming or shutting down of entire institutes in other locations arrangement which codified the common and sole responsibility of the individual states con- cerning the financial furthering of research and recognized the necessity of a permanent institutional funding for research. MPS continued with the founding of new institutes.The qualitative and tem- poral dimensions of the establishment program became a test of stress and strain for the scientific committees.With the