applications of biotechnology in cardiovascular therapeutics

[...]... Role of NO in the Pathophysiology of Angina Pectoris Role of NO in the Pathophysiology of Congestive Heart Failure Myocardial Ischemia/Reperfusion Injury Role of NO in Management of Cardiovascular Disorders Role of NO in Cardioprotection Role of NO in the Management of Angina Pectoris Role of NO in Therapy of Coronary Heart Disease NO-Releasing Aspirin in Patients... Prediction of Death from Cardiovascular Disease Role of Biomarkers in the Management of Cardiovascular Disease Role of Biomarkers in the Diagnosis/Prognosis of Myocardial Infarction Role of Biomarkers in the Prevention of Cardiovascular Disease Molecular Signature Analysis in Management of Cardiovascular Diseases C-Reactive Protein as Biomarker of Response to Statin Therapy... by Humana/Springer His other recent books include Handbook of Nanomedicine (Springer/Humana 2008), Textbook of Personalized Medicine (Springer 2009), Handbook of Biomarkers (Springer 2010), and Handbook of Neuroprotection (Springer 2011) xi Contents 1  Cardiovascular Therapeutics Introduction History of Cardiovascular Therapy Overview of Cardiovascular. .. Role of Circulating Biomarkers and Mediators of Cardiovascular Dysfunction Use of Protein Biomarkers for Monitoring Acute Coronary Syndromes Use of Biomarkers for Prognosis of Recurrent Atrial Fibrillation Use of Multiple Biomarkers for Monitoring of Cardiovascular Disease Use of Biomarkers in the Management of Peripheral Arterial Disease Use of Biomarkers in. .. Currently, he is a Fellow of the Royal Australasian College of Surgeons and a Fellow of the Faculty of Pharmaceutical Medicine of the Royal College of Physicians of UK Prof Jain is the author of 425 publications including 18 books (2 as editor) and 49 special reports, which have covered important areas in neurosciences, biomedicine, biotechnology, cell/gene therapy, and biopharmaceuticals In the 1970s, he developed... Author Professor Kewal K Jain is a neurologist/neurosurgeon by training and since his retirement from neurosurgery has been working in the biotechnology/ biopharmaceuticals industry as a consultant at Jain PharmaBiotech He received graduate training in both Europe and North America and has held academic positions in several other countries He passed specialist examinations in neurosurgery in USA, Canada,... NO and Pulmonary Circulation Role of NO in Pathomechanism of Cardiovascular Disorders Oxidative Stress as a Cause of Cardiovascular Disease Role of NO in Pathomechanism of Cardiovascular Diseases NO and Atherosclerosis Role of NO in Cardiopulmonary Disorders Role of NO in Disturbances of Vasodilation Role of NO in Hypercholesterolemia 38 39 40 41 42... 94 Introduction Biomarkers of Cardiovascular Diseases Methods for Identification of Cardiovascular Biomarkers Application of Proteomics for Biomarkers of Cardiovascular Disease Detection of Biomarkers of Myocardial Infarction in Saliva by a Nanobiochip Metabolomic Technologies for Biomarkers of Myocardial Ischemia Imaging Biomarkers of Cardiovascular. .. small that it heals almost instantly Illustrations courtesy of Mercator MedSystems Fig. 3.1 Biosynthesis of nitric oxide (NO) L-arginine is converted to NO in two successive steps of which a two-electron oxidation of L-arginine to N-w-hydroxy-L-argininine is the first, then converted to NO and citrulline, utilizing one and half NADPH and O2 Both steps require Ca2+ and calmodulin as activators and are... supply In addition to the usual formulations of drugs such as controlled release, devices are used as well A considerable amount of cardiovascular therapeutics, particularly for major and serious disorders, involves the use of devices Some of these may be implanted by surgery whereas others are inserted via minimally invasive procedures involving catheterization Use of sophisticated cardiovascular imaging . w0 h0" alt="" Applications of Biotechnology in Cardiovascular Therapeutics Applications of Biotechnology in Cardiovascular Therapeutics Kewal K. Jain MD, FRACS, FFPM Jain PharmaBiotech,. 80 Role of NO in Cardioprotection 80 Role of NO in the Management of Angina Pectoris 81 Role of NO in Therapy of Coronary Heart Disease 82 NO-Releasing Aspirin in Patients Undergoing CABG. Role of NO in the Pathophysiology of Angina Pectoris 76 Role of NO in the Pathophysiology of Congestive Heart Failure 77 Myocardial Ischemia/Reperfusion Injury 78 Role of NO in Management of Cardiovascular