Lecture Notes in Computer Science 4987 Commenced Publication in 1973 Founding and Former Series Editors: Gerhard Goos, Juris Hartmanis, and Jan van Leeuwen Editorial Board David Hutchison Lancaster University, UK Takeo Kanade Carnegie Mellon University, Pittsburgh, PA, USA Josef Kittler University of Surrey, Guildford, UK Jon M. Kleinberg Cornell University, Ithaca, NY, USA Alfred Kobsa University of California, Irvine, CA, USA Friedemann Mattern ETH Zurich, Switzerland John C. Mitchell Stanford University, CA, USA Moni Naor Weizmann Institute of Science, Rehovot, Israel Oscar Nierstrasz University of Bern, Switzerland C. Pandu Rangan Indian Institute of Technology, Madras, India Bernhard Steffen University of Dortmund, Germany Madhu Sudan Massachusetts Institute of Technology, MA, USA Demetri Terzopoulos University of California, Los Angeles, CA, USA Doug Tygar University of California, Berkeley, CA, USA Gerhard Weikum Max-Planck Institute of Computer Science, Saarbruecken, Germany Xiaohong Gao Henning Müller Martin Loomes Richard Comley Shuqian Luo (Eds.) Medical Imaging and Informatics 2nd International Conference, MIMI 2007 Beijing, China, August 14-16, 2007 Revised Selected Papers 13 Volume Editors Xiaohong Gao Martin Loomes Richard Comley Middlesex University School of Computing Science The Burroughs NW4 4BT London, United Kingdom E-mail: {x.gao; m.loomes; r.comley}@mdx.ac.uk Henning Müller University of Applies Sciences Sierre TecnoArk 3 3960 Sierre, Switzerland E-mail: henning.mueller@sim.hcuge.ch Shuqian Luo Capital Medical University No. 10 Xitoutiao You An Men 100069 Beijing, China E-mail: shuqian_liu@yahoo.com.cn Library of Congress Control Number: 2008930311 CR Subject Classification (1998): I.4, I.5, I.2.10, J.3, I.3 LNCS Sublibrary: SL 6 – Image Processing, Computer Vision, Pattern Recognition, and Graphics ISSN 0302-9743 ISBN-10 3-540-79489-1 Springer Berlin Heidelberg New York ISBN-13 978-3-540-79489-9 Springer Berlin Heidelberg New York This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. Springer is a part of Springer Science+Business Media springer.com © Springer-Verlag Berlin Heidelberg 2008 Printed in Germany Typesetting: Camera-ready by author, data conversion by Scientific Publishing Services, Chennai, India Printed on acid-free paper SPIN: 12263424 06/3180 543210 Preface This series constitutes a collection of selected papers presented at the International Conference on Medical Imaging and Informatics (MIMI2007), held during August 14–16, in Beijing, China. The conference, the second of its kind, was funded by the European Commission (EC) under the Asia IT&C programme and was co-organized by Middlesex University, UK and Capital University of Medical Sciences, China. The aim of the conference was to initiate links between Asia and Europe and to exchange research results and ideas in the field of medical imaging. A wide range of topics were covered during the conference that attracted an audience from 18 countries/regions (Canada, China, Finland, Greece, Hong Kong, Italy, Japan, Korea, Libya, Macao, Malaysia, Norway, Pakistan, Singapore, Switzerland, Taiwan, the United Kingdom, and the USA). From about 110 submitted papers, 50 papers were selected for oral presentations, and 20 for posters. Six key-note speeches were delivered during the conference presenting the state of the art of medical informatics. Two workshops were also organized covering the topics of “Legal, Ethical and Social Issues in Medical Imaging” and “Informatics” and “Computer-Aided Diagnosis (CAD),” respectively. This series presents the cutting-edge technology applied in the medical field, which can be epitomized by the second and sixth papers in the session of “Medical Image Segmentation and Registration,” on the application of bio-mimicking techniques for the segmentation of MR brain images. Paper 4 in the session of “Key-Note Speeches” describes the pioneering work on frameless stereotactic operations for the removal of brain tumors, whereas the paper entitled “CAD on Brain, Fundus, and Breast” was presented in the session of “Computer-Aided Detection (CAD).” A special tribute is paid to Paolo Inchingolo from the University of Trieste, Italy, one of the key-note speakers, who sadly passed away due to sudden illness. Professor Inchingolo specialized in health-care systems and tele-imaging. His paper appears as the second in the session of “Key-Note Speeches.” The editors would like to thank the EC for their financial support and also the China Medical Informatics Association (CMIA) for their support. Special thanks go to the reviewers who proof-read the final manuscripts of the papers collected in this book, in particular, Tony White, Ray Adams, Stephen Batty, Christian Huyck, and Peter Passmore. January 2008 Xiaohong Gao Henning Müller Martin Loomes Richard Comley Shuqian Luo Organization Committee General Co-chairs Debing Wang, China Martine Looms, UK Davide Caramella, Italy Executive Chair Yongqin Huang, China Program Co-chairs Shuqian Luo, China Edward M. Smith, USA Publication Chair Henning Müller, Switzerland Organizing Committee Chair Ying Liang, China Organization Chair Xiaohong Gao, UK International Programme Committee David Al-Dabass, Norttingham Trent University, UK Yutaka Ando, National Institute of Radiological Sciences, Japan Franclin Aigbithio, Wolfson Brain Imaging Centre, Cambridge, UK Richard Bayford, Middlesex University, UK Stephen Batty, Institute of Cognitive Neuroscience, UCL, UK Roald Bergstrøm, President of the 24th EuroPACS Conference, Norway Hans Blickman, Dept. of Radiology UMC, Netherlands Jyh-Cheng Chen, National Yang-Ming University, Taiwan, China Hune Cho, Kyungpook National University, Korea John Clark, University of Cambridge, UK Richard Comley, Middlesex University, UK Andrzej Czyzewski, Gdansk University of Technology, Poland Robert Ettinger, Middlesex University, UK Mansoor Fatehi, Iranian Society of Radiology, Iran Huanqing Feng, University of Science and Technology of China Haihong Fu, Beijing Union Hospital, China Hiroshi Fujita, Gifu University, Japan W. Glinkowski, Medical University of Warsaw, Poland Sean He, University of Technology, Sydney, Australia H.K. Huang, University of California San Francisco, USA Jacob Hygen, KITH, Norway Paolo Inchingolo, Universita' di Trieste, Italy Theodore Kalamboukis, Athens University of Economics and Business, Greece Myeng-ki Kim, Seoul National University, Korea VIII Organization Michio Kimura, Hamamatsu University, Japan Inger Elisabeth Kvaase, Directorate for Health and Social Affairs, Norway Thomas Lehmann, Aachen University, Germany Hua Li, Institute of Computing Technology, China Qiang Lin, Fuzhou University, China Subin Liu, Peking University, China Tianzi Jiang, National Laboratory of Pattern Recognition, China Peter Passmore, Middlesex University, UK Lubov Podladchikova, Rostov State University, Russia Hanna Pohjonen, Consultancy of Healthcare Information Systems, Finland Jan Størmer, UNN, Tromso, Norway Egils Stumbris, Riga Municipal Telemedicine Centre, Latvia Yankui Sun, Tsinghua University, China Yin Leng Theng, Nanyang Technological University, Singapore Simon Thom, St Mary’s Hospital, UK Zengmin Tian, Navy General Hospital, China Federico Turkheimer, Hammersmith Hospital, UK Baikun Wan, Tianjin University, China Boliang Wang, Xiamen University, China Jim Yang, KITH, Norway Jiwu Zhang, Eastman Kodak Company, China Guohong Zhou, Capital University of Medical Sciences, China Sponsors European Commission IT&C Programmes China Medical Informatics Association, China Middlesex University, UK Capital University of Medical Sciences, China Table of Contents Keynote Speeches Complexity Aspects of Image Classification 1 Andreas A. Albrecht The Open Three Consortium: An Open-Source Initiative at the Service of Healthcare and Inclusion 5 Paolo Inchingolo Extending the Radiological Workplace Across the Borders 12 Hanna Pohjonen, Peeter Ross, and Johan (Hans) Blickman From Frame to Framless Stereotactic Operation—Clinical Application of 2011 Cases 18 Zeng-min Tian, Wang-sheng Lu, Quan-jun Zhao, Xin Yu, Shu-bin Qi, and Rui Wang Medical Image Segmentation and Registration Medical Image Segmentation Based on the Bayesian Level Set Method 25 Yao-Tien Chen and Din-Chang Tseng A Worm Model Based on Artificial Life for Automatic Segmentation of Medical Images 35 Jian Feng, Xueyan Wang, and Shuqian Luo An Iterative Reconstruction for Poly-energetic X-ray Computed Tomography 44 Ho-Shiang Chueh, Wen-Kai Tsai, Chih-Chieh Chang, Shu-Ming Chang, Kuan-Hao Su, and Jyh-Cheng Chen Application of Tikhonov Regularization to Super-Resolution Reconstruction of Brain MRI Images 51 Xin Zhang, Edmund Y. Lam, Ed X. Wu, and Kenneth K.Y. Wong A Simple Enhancement Algorithm for MR Head Images 57 Xiaolin Tian, Jun Yin, Yankui Sun, and Zesheng Tang A Novel Image Segmentation Algorithm Based on Artificial Ant Colonies 63 Huizhi Cao, Peng Huang, and Shuqian Luo X Table of Contents Characteristics Preserving of Ultrasound Medical Images Based on Kernel Principal Component Analysis 72 Tongsen Hu and Ting Gui Robust Automatic Segmentation of Cell Nucleus Using Multi-scale Space Level Set Method 80 Chaijie Duan, Shanglian Bao, Hongyu Lu, and Jinsong Lu Principal Geodesic Analysis for the Study of Nonlinear Minimum Description Length 89 Zihua Su, Tryphon Lambrou, and Andrew Todd-Pokropek Medical Informatics Learning a Frequency–Based Weighting for Medical Image Classification 99 Tobias Gass, Adrien Depeursinge, Antoine Geissbuhler, and Henning M¨uller Greek-English Cross Language Retrieval of Medical Information 109 E. Kotsonis, T.Z. Kalamboukis, A. Gkanogiannis, and S. Eliakis Interest Point Based Medical Image Retrieval 118 Xia Zheng, MingQuan Zhou, and XingCe Wang Texture Analysis Using Modified Computational Model of Grating Cells in Content-Based Medical Image Retrieval 125 Gang Zhang, Z.M. Ma, Zhiping Cai, and Hailong Wang A New Solution to Changes of Business Entities in Hospital Information Systems 133 Zhijun Rong, Jinsong Xiao, and Binbin Dan A Software Client for Wi-Fi Based Real-Time Location Tracking of Patients 141 Xing Liu, Abhijit Sen, Johannes Bauer, and Christian Zitzmann Significance of Region of Interest Applied on MRI and CT Images in Teleradiology-Telemedicine 151 Tariq Javid Ali, Pervez Akhtar, M. Iqbal Bhatti, and M. Abdul Muqeet PET, fMRI, Ultrasound and Thermal Imaging Gender Effect on Functional Networks in Resting Brain 160 Liang Wang, Chaozhe Zhu, Yong He, Qiuhai Zhong, and Yufeng Zang Table of Contents XI Transferring Whole Blood Time Activity Curve to Plasma in Rodents Using Blood-Cell-Two-Compartment Model 169 Jih-Shian Lee, Kuan-Hao Su, Jun-Cheng Lin, Ya-Ting Chuang, Ho-Shiang Chueh, Ren-Shyan Liu, Shyh-Jen Wang, and Jyh-Cheng Chen Prototype System for Semantic Retrieval of Neurological PET Images 179 Stephen Batty, John Clark, Tim Fryer, and Xiaohong Gao Evaluation of Reference Tissue Model for Serotonin Transporters Using [ 123 I] ADAM Tracer 189 Bang-Hung Yang, Shyh-Jen Wang, Yuan-Hwa Chou, Tung-Ping Su, Shih-Pei Chen, Jih-Shian Lee, and Jyh-Cheng Chen A Fast Approach to Segmentation of PET Brain Images for Extraction of Features 197 Xiaohong Gao and John Clark New Doppler-Based Imaging Method in Echocardiography with Applications in Blood/Tissue Segmentation 207 Sigve Hovda, H˚avard Rue, and Bjørn Olstad Comparison of Chang’s with Sorenson’s Attenuation Correction Method by Varying Linear Attenuation Coefficient Values in Tc-99m SPECT Imaging 216 Inayatullah Shah Sayed, Ahmed Zakaria, and Norhafiza Nik An Improved Median Filtering System and Its Application of Calcified Lesions’ Detection in Digital Mammograms 223 Kun Wang, Yuejian Xie, Sanli Li, and Yunpeng Chai Bandwidth of the Ultrasound Doppler Signal with Applications in Blood/Tissue Segmentation in the Left Ventricle 233 Sigve Hovda, H˚avard Rue, and Bjørn Olstad 3D Reconstruction and Visualization Applications of the Visible Korean Human 243 Jun Won Lee, Min Suk Chung, and Jin Seo Park Preliminary Application of the First Digital Chinese Human 252 Yuan Yuan, Lina Qi, and Shuqian Luo 3D Head Reconstruction and Color Visualization of Chinese Visible Human 262 Fan Bao, Yankui Sun, Xiaolin Tian, and Zesheng Tang XII Table of Contents A Fast Method to Segment the Liver According to Couinaud’s Classification 270 Shao-hui Huang, Bo-liang Wang, Ming Cheng, Wei-li Wu, Xiao-yang Huang, and Ying Ju The Application of Watersnakes Algorithm in Segmentation of the Hippocampus from Brain MR Image 277 Xiang Lu and Shuqian Luo Spiral MRI Reconstruction Using Least Square Quantization Table 287 Dong Liang, Edmund Y. Lam, George S.K. Fung, and Xin Zhang A Hybrid Method for Automatic and Highly Precise VHD Background Removal 294 Chen Ding, Yankui Sun, Xiaolin Tian, and Zesheng Tang Analytic Modeling and Simulating of the Cornea with Finite Element Method 304 Jie-zhen Xie, Bo-liang Wang, Ying Ju, and Shi-hui Wu An Improved Hybrid Projection Function for Eye Precision Location 312 Yi Li, Peng-fei Zhao, Bai-kun Wan, and Dong Ming Spectropolarimetric Imaging for Skin Characteristics Analysis 322 Yongqiang Zhao, TieHeng Yang, PeiFeng Wei, and Quan Pan Image-Based Augmented Reality Model for Image-Guided Surgical Simulation 330 Junyi Zhang and Shuqian Luo Workshops Legal, Ethical and Social Issues in Medical Imaging and Informatics What ELSE? Regulation and Compliance in Medical Imaging and Medical Informatics 340 Penny Duquenoy, Carlisle George, and Anthony Solomonides Computer-Aided Diagnosis (CAD) CAD on Brain, Fundus, and Breast Images 358 Hiroshi Fujita, Yoshikazu Uchiyama, Toshiaki Nakagawa, Daisuke Fukuoka, Yuji Hatanaka, Takeshi Hara, Yoshinori Hayashi, Yuji Ikedo, Gobert N. Lee, Xin Gao, and Xiangrong Zhou [...]... information organizations) and citizens (care at home and on the move, and ambient assisted living), based on about 60 HECE bilateral cooperation Agreements with Hospitals, Medical Research Centers, Healthcare Enterprises, Industrial Enterprises and Governmental Agencies and on the International Networks ABIC-BME (Adriatic Balcanic Ionian Cooperation on Biomedical Engineering) and ALADIN (Alpe Adria Initiative... committee in Central and Eastern Europe?” The IHE Workshop closed with the commitment to HECE of creating a transnational IHE committee for the Central and Eastern Europe, dealing with technical, harmonization and law-orienting activities in 22 Central and Eastern European Countries Second, the same round table and most of the IHE workshop sessions underlined that the adoption of open standards and open source... participate in both communities The Developers community started under the responsibility and administration of HECE, with main contributions from the Universities of Trieste and Padova, and lately Maribor in Slovenia, and grew with many other European and US contributions, from universities and research centers and from industries It provides the active members of the Users’ Community with all the necessary... solving, and high-level 24/7 full-risk service Additionally, training is highly cared by HECE, starting with preparing clinical engineering professionals at three different levels, offering both traditional and e-learning courses with particular skills in Clinical Informatics, Health Telematics, E-health integration standards and IHE-based interoperability, and also provision of specific courses and training... combinations of local and remote processing of medical data 3 Results The main advantages of streaming technology include 1) Effective use of bandwidth: streaming technology can use bandwidth in a manner that can be well estimated, and in many cases such bandwidth usage is more efficient than with traditional web-based solutions (involving data downloading) 2) Increased security and data consistency:... features and interfaces on all access devices and at all locations, users become more comfortable, efficient and standardized regarding daily workflows Handheld mobile/wireless devices can provide clinicians with enterprise-wide access to all patient data and analysis tools on a pervasive basis 4) Predictable scalability: streaming systems scale linearly with the number of users, the number of sites, and. .. known and accepted processes and protocols, transparency, possibilities for peer review and double blind readings from time to time On the other hand, the service provider expects access to the relevant data, feedback on discrepancies and learning from other specialists 16 H Pohjonen, P Ross, and J.(H.) Blickman Feedback – both from radiologists but also from clinicians - is essential in building and. .. Trieste [1], the Group of Bioengineering and ICT and the Higher Education in Clinical Engineering (HECE) of the University of Trieste started the project DPACS (Data and Picture Archiving and Communication System) in 1995 The goal of DPACS (Figure 2) was “the development of an open, scalable, cheap and universal system with accompanying tools, to store, exchange and retrieve all health information of... as Open Source and with Java and Web technologies, being independent of database, OS, HW and language and 100% compliant with the IHE world-wide interoperability initiative, its reuse and portability are facilitated, fostering wide distribution in the world The choice of Open Source as the leading solution of O3 for the future of e-health anticipates a common trend in the industrialized and political... updates The platform is adjustable for different end-terminals and network bandwidths and overall training times can be significantly reduced By introducing systems that minimize support and maintenance the overall burden on IT departments can be greatly reduced Web client applications can be thin and thus require minimal configuration and setup activities on the client side This is important for today’s . state of the art of medical informatics. Two workshops were also organized covering the topics of “Legal, Ethical and Social Issues in Medical Imaging and Informatics and “Computer-Aided. Regulation and Compliance in Medical Imaging and Medical Informatics 340 Penny Duquenoy, Carlisle George, and Anthony Solomonides Computer-Aided Diagnosis (CAD) CAD on Brain, Fundus, and Breast. Wei, and Quan Pan Image-Based Augmented Reality Model for Image-Guided Surgical Simulation 330 Junyi Zhang and Shuqian Luo Workshops Legal, Ethical and Social Issues in Medical Imaging and Informatics What