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Marrone 2007 fungicide

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PowerPoint Presentation Milsana® Fungicide Nick Macris Director, Business Development nmacrismarroneorganics com (727) 742 2571 (mobile) (530) 750 2800 (office) www marroneorganics com 1 Source Extra.

Milsana® Fungicide Nick Macris Director, Business Development nmacris@marroneorganics.com (727) 742-2571 (mobile) (530) 750-2800 (office) www.marroneorganics.com Milsana® Fungicide Overview  Source: Extract from giant knotweed Reynoutria sachalinensis (REYSA)  Target pathogens: Milsana® effectively controls powdery mildew, gray mold, rust, and bacterial blight on ornamental plants and edible crops  Mode of Action: Induction of plant defense responses – – – – –  Reactive oxygen species Enzymes of the phenolic pathway Lignification of cell walls Papilla formation Phytoalexins Has EPA crop and non crop registrations as biochemical biopesticide California - non crop label only Milsana® Label Recommendations  Apply at the rate of 0.5-1.0% in 50 to 100 gallons of water per acre  Add 0.02% wetting agent such as Nu-Film P  Use the spray mixture preventatively at the 4-6 leaf plant stage and repeat spraying every 7-14 days depending on disease pressure Milsana® on Ornamentals  Begonias  Freesias  Lisianthus  Poinsettias  Salvias  Zinnias  Crape  Gerbera myrtle  Petunias  Snapdragons  Roses Diseases Powdery Mildew (Oidium spp) Gray Mold (Botrytis cinerea) Rust (Puccinia antirrhini) Milsana® on Food Crops  Cucumbers  Strawberries  Melons  Lettuce  Squash  Pumpkins  Grapes  Tomatoes  Peppers * Diseases Powdery Mildew (Sphaerotheca spp, Erysiphe cichoracearum ) Gray Mold (Botrytis cinerea) Bacterial blight (Xanthomonas campestris)* Summary of Milsana® Activity Summary of REYSA Extract Activity on Various Edible Crops and Diseases, 1994-2001 Crop / Plant Cucumbers Diseases Sphaerotheca fuliginea Induction Activity +++ Squash S fuliginea +++ Melons S fuliginea +++ Grapes Uncinula necator +++ Peppers Xanthomonas spp ++ Pumpkin S fuliginea ++ Lettuce Erysiphe cichoriasearum ++ Strawberries S macularis ++ Wheat Erysiphe graminis ++ Beans Botrytis cinerea Sclerotinia + (-) Field Data Grape powdery mildew trial, (W.D Gubler, Univ of California, Davis, July 2000) Trt# Product, sequence (among 24 combinations tested) Severity % Incidence % Untreated 62.0 a 100 a Serenade® WP + Rally® WP, 7x 4.0 b 40.0 b Milsana®, 7x 2.2 b 28.8 b Mankocide® + Microthiol® 80 DF, 5x 2.0 b and Sulfur 80 DF, 7x 32.5 b Sulfur 80 DF 1x followed by Procure® 50 WS + Sulfur 80 DF,7x 1.3 b 21.3 b Serenade® WP, (low) 13x 1.2 b 33.1 b Abound® 2.08 SC, 7x 0.5 b 13.8 b Field Data Botrytis disease ratings and yield of “Trust” Tomatoes (Central Mississippi Research Center, 2003) Treatment Disease Marketable yield rating per plant (lb) (0-100%) Untreated Control 53.3 a 9.6 a Milsana® 26.7 b 11.4 b Elevate® 50WG 16.7 b 11.2 b Switch® 62.5 WG 26.7 b 11.4 b Serenade® 20.0 b 10.7 a Scala® 53.3 a 10.7 a Regulatory/Toxicology  Current EPA registration for crop and non crop (ornamentals) uses  CA non crop label only (MOI will submit crop label by the end of 2007)  More targets will be added (e.g tomato, turf)  All other crops and diseases are opportunities for IR-4 priorities MOI is working on an organic formulation  Potential IR-4 Projects  Test Milsana® as part of IPM programs in ornamentals, vegetables, fruit, vines (Botrytis, mildews, bacterial diseases Other diseases ?  Test Milsana® on turf diseases  Test efficacy against other pathogens, such as oomycetes (Phytophthora spp and downy mildew) ...Milsana® Fungicide Overview  Source: Extract from giant knotweed Reynoutria sachalinensis (REYSA)  Target... non crop (ornamentals) uses  CA non crop label only (MOI will submit crop label by the end of 2007)  More targets will be added (e.g tomato, turf)  All other crops and diseases are opportunities

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