patients with schizophrenia show aberrant patterns of basal ganglia activation evidence from ale meta analysis

Accepted Manuscript Patients with schizophrenia show aberrant patterns of basal ganglia activation: Evidence from ALE meta-analysis Jessica A Bernard, Courtney E Russell, Raeana E Newberry, James R.M Goen, Vijay A Mittal PII: DOI: Reference: S2213-1582(17)30034-7 doi: 10.1016/j.nicl.2017.01.034 YNICL 944 To appear in: NeuroImage: Clinical Received date: Revised date: Accepted date: 18 October 2016 23 December 2016 31 January 2017 Please cite this article as: Jessica A Bernard, Courtney E Russell, Raeana E Newberry, James R.M Goen, Vijay A Mittal , Patients with schizophrenia show aberrant patterns of basal ganglia activation: Evidence from ALE meta-analysis The address for the corresponding author was captured as affiliation for all authors Please check if appropriate Ynicl(2017), doi: 10.1016/j.nicl.2017.01.034 This is a PDF file of an unedited manuscript that has been accepted for publication As a service to our customers we are providing this early version of the manuscript The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT Highlights -The basal ganglia are connected to the cortex through multiple parallel circuits • -Basal ganglia function has been implicated in patients with schizophrenia • -Meta-analysis demonstrated a functional activation topography in the basal ganglia • -Patients with schizophrenia show a decrease in basal ganglia activity across studies • -These are important for our understanding of symptoms in this clinical population AC CE PT ED M AN US CR IP T • ... functional activation topography in the basal ganglia • -Patients with schizophrenia show a decrease in basal ganglia activity across studies • -These are important for our understanding of symptoms... Highlights -The basal ganglia are connected to the cortex through multiple parallel circuits • -Basal ganglia function has been implicated in patients with schizophrenia • -Meta- analysis demonstrated... MANUSCRIPT AC CE PT ED M AN US CR IP T ACCEPTED MANUSCRIPT , and are subsequently relaying the output of these neural computations back to the cortical targets AC CE PT ED M AN US CR IP T ACCEPTED