1365 an inflammation inducible adenoviral expression system for local treatment of the arthritic joints

1365 An Inflammation Inducible Adenoviral Expression System for Local Treatment of the Arthritic Joints Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts Copyright © The American Society of G[.]

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"         "                      1364 Adenoviral Gene Therapy for Renal Cancer Requires Retargeting to Alternative Cellular Receptors Yosef S Haviv,1,2 Jerry L Blackwell,1,2 Anna Kanerva,1,2 Peter Nagi,1,2 Victor Krasnykh,1,2 Igor Dmitriev,1,2 Seiji Naito,3 Akseli Hemminki,1,2 David T Curiel.1,2 Division of Human Gene Therapy, Departments of Medicine, Pathology, and Surgery, University of Alabama at Birmingham, Birmingham, AL, United States; 2Gene Therapy Center, University of Alabama at Birmingham, Birmingham, AL, United States; Department of Urology, Graduate School of Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan #       -@/          "      0                 @                                              @              -' /                C         "  "                               "                       "E    "   '                     )            '                           3        '       3          -'@/           '              @               @  3       '        '@ 3    @   '             3          =   &  3      '   =  1      '      @               "   '              @$     C     '             ' &     ' =            '@       @        "    '                 G  '@"    @          3  "   '     0  "   ' &              @    "   "   '              @      ?     "          3  "   '     "   '  * 3            "    "   '          @   @    "      "     Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy ' &%==        '    =      @       @    "        '     E               ' &%==          "  @                       ' &%==@3              @            @    '@"         G        ' &          @        @     1  @        '           ' =                3  "   '      '@              "     '       1                 3  '@"                   '@"            @       1                  @        '@"         !!"7" ""   1365 An Inflammation-Inducible Adenoviral Expression System for Local T reatment of the Arthritic Treatment Joints Fons A J van de Loo,1 Andrew C Bakker,1 Miranda B Bennink,1 Onno J Arntz,1 Wim B van den Berg.1 Rheumatology, University Medical Center Nijmegen, Nijmegen, Netherlands )E          "       3       "             #   ' "                "8     - "=B59  ",;,9/       D"B     - "8B=  J8,/    -D"8%D"B/  D=D       -!  /             3             "  -C":,/            " -@'0 ,B6;/ @          & ->8   >=   /          3      -D/         D"8%D"B         D 3           #.    '          588   ->8"         /  @'         !?4            O 899 !           @'0        G - "      /"      -N'/    @   N'      E            -D/"8   D"B    E ?     D"8             D"B         "      C":,             D="DD="D"B"D  D="D"8%D"B" D        "             !#'-89%/JD!(-,9%/J '#!-899#/        8:      ' 8="     D     D="D"8%D"B"D                    ' 86"       @'0          D="D"8%D"B"D        ="         D="D"B"D          D"8            D"B   * 3@'0    ' &#."D ' &D"8%D" B"D -#)  89/   ,6"           D!( -, %/ ' ,="     D      ' &D"8%D"B" D      6B" ' &#." D      #    "    D!(      "    ' &D"8%D"B"D       ,9"                N'            89>B !?4 ' &D"8%D"B"D     =5"      D  A      ' &#."D       S447 !!"7" ""        >        D"8%   D"B      "       D"8%D"B      1  D"8   D"B   D"8  %D"B                 "      D!(      E                #.          D" 8%D"B           "     3     "         1366 Control of Protein Systemic Delivery by Hypoxia Using a tet-HIF1-Alpha Chimeric T ransactivator Transactivator Delphine Bohl, Jean-Michel Heard Neuroscience, Institut Pasteur, Paris, France          ->/         ),                       "          >                                 3     -),/              C?"8           3      ),                  '                             -C '/      3 -,8H 3 / (         C '    1        3       ,,′"     3                 #8=, C D            3                          #              >        -    /   3       C '                  89  ,9           8H 3        ,,′"     3     #8=, D                         ''.",         ''.      "8"  $*'         #.              >           ''.      C ' 3         #.    *      E   #      E          "8"    G      , %        ;H 3    ,6   '       "8"     88                           6:           3                      ),                                                        1367 Long T erm Reversal of Chronic Anemia Using a Term Hypoxia Regulated Erythropoietin Gene Therapy Katie Binley,1 Zoe Askham,1 Sharifah Iqball,1 Hayley Spearman,1 Leigh Martin,1 Mahesh De Alwis,2 Adrian Thrasher,2 Susan Kingsman,1 Stuart Naylor.1 Oxford BioMedica (UK) Ltd, Oxford, Oxfordshire, United Kingdom; 2Molecular Immunology Unit, Institute of Child Health, London, United Kingdom                                        '                   ->/                               >                  > '             3      >         3   -)2C@>/         -#./     )2C@>">               >" '         S448      :9                         >" '                 "               >" '                          )2C@>">    >" '                               > 3         #.%>                                )2C@>           >                           >" '                      >          3      3           >    1368 T ranscriptional T argeting of Heterologous Transcriptional Targeting Genes to the Liver using Chimeric Promoters: In Vitro and In Vivo Comparative Study Maria G Kramer,1 Miguel A Barajas,1 Maider Zabala,1 Nerea Razquin,1 Pedro Berraondo,1 Manuel Rodrigo,1 Jesus M Prieto,1 Puri Fortes.1 Depart Internal Medicine, CIMA-University of Navarra, Pamplona, Navarra, Spain                                                 3               3G                3                          (                                                          #.  2         8"     3    '                              >3                                        "                               3                   !                  -!>/           E     $*'          )        -       /                       #.        3  89  899                         !                899      C2.                                            3   "                          1           ,       8H    #.                                        1369 T umor-Specific Induction of Retroviral V ector Tumor-Specific Vector Production Using Cell Based Carriers for Cancer Gene Therapy Marka Crittenden,1 Dragan Jevremovic,1 Michael Gough,1 Anja Ruchatz,1 John Chester,2 Victor Rivera,3 Tim Clackson,3 Francois Loic Cosset,4 Luis Alvarez-Vallina,5 Richard Vile.1 Molecular Medicine Program, Mayo Clinic, Rochester, MN, United States; 2ICRF Oncology Unit, St James Hospital, Leeds, United Kingdom; 3ARIAD Gene Therapeutics, Cambridge, MA, United States; 4INSERM U412, Lyon, France; 5Department of Immunology, Hospital Universitario Clinica Puerta de Hierro, Madrid, Spain                                                                               Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy ... Division of Human Gene Therapy, Departments of Medicine, Pathology, and Surgery, University of Alabama at Birmingham, Birmingham, AL, United States; 2Gene Therapy Center, University of Alabama...     1364 Adenoviral Gene Therapy for Renal Cancer Requires Retargeting to Alternative Cellular Receptors Yosef S Haviv,1,2 Jerry L Blackwell,1,2 Anna Kanerva,1,2 Peter Nagi,1,2... Birmingham, Birmingham, AL, United States; Department of Urology, Graduate School of Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan #       -@/