585 genomic integration and stable transgene expression provided by high capacity adeno associated virusadenovirus hybrid vector transduction

585 Genomic Integration and Stable Transgene Expression Provided by High Capacity Adeno Associated Virus/Adenovirus Hybrid Vector Transduction Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Part[.]

!" " "                                          E                           ''           #);    -          /  89     E  ''. ->?! 3   /   C( ''."!D8&H>?! 3    -?4"#>##/ O8H''.             6       3               ''.              C( #                       ''."              ''.      ) 3         3        ''.           C(  "     "     583 A cis-Acting Element That Directs Exclusively Circular Adeno-Associated Virus Replication Sergei A Musatov, Jill Roberts, Donald Pfaff, Michael Kaplitt '       "     -''./                 3     -''./                3  89H      3      G  -  @  /   ''.           @     $"    -$"'′"2′"2"′""'"$/ 0        ''                   ''.    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G            G                       G  3  86     Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy  !                    ''         "        3                  584 Improvement of T ransduction Efficiency from Transduction Split AA VV ectors AAV Vectors Liqiao Zhou,1 Liangwu Sun,1 Juan Li,1 Xiao Xiao.1 Department of Molecular Genetics and Biochemistry, University of Pittsburgh, Pittsburgh, PA, United States ' "     -''./                         )         ''.         -& /                             @               -(   * #  ,999/    ( ''     ('.>       G                 &  C       3            ''.           ''.               ''.                  C          ''.       3                      3      ? 3  4.              $*'                           3             ''    C    "              3       ''.                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(     !@         $*'           "            ''.        1           " ''.% '              "         3                          $*'    586 Unstability of T etracycline-Dependent T ransgene Tetracycline-Dependent Transgene Expression in the Skeletal Muscle after DNA Electrotransfer Norma L Perez, Jèrôme Poupiot, Evelyne Gicquel, Sabrina Turbant, Baudry Laetitia, Boussat Sandrine, Danos Olivier Therapeutic Strategies, Genethon III/CNRS URA 1923, Evry, France       "   -  '/   1            3          C                     3          -$3 /                 - (/                 A@'2"'2      "8                     $3              (      '     )          '    2%                  D   3       =                      (            C                       3            ;9"59H    ;           998H      $3      ,  0    E    '  (            ;      @*'    '         86 @ !@ 3   E                                                     -&9%/         E     8            3    $3       '          ''                                      3                       )                                   '% ( 3   -,&   89       /                                                   587 Interferon-b Gene Therapy for Human Glioma Cells by Heat-Inducible Adeno-Associated V irus V ectors Virus Vectors and Low-T emperature Hyperthermia Low-Temperature Masaaki Mizuno,1 Yoshida Jun.2 Molecular Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya, Japan; 2Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya, Japan                    " -?*"/       "    "      -''./        "          ''.       ?*" -C?*"/                ;92 -C(!;92/   -''." 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"?*"     "        *   G                  588 Insertion of Peptides into VP1 and VP2 Sequences Influences the Stoichiometry of AA V2 Capsid AAV2 Proteins Lei Cao,1 Xiangyang Jiao,1 Yuhong Liu,1 Weidong Xiao,2 Matthew J During.1 CNS Gene Therapy Center, Department of Neurosurgery, Thomas Jefferson University, Philadelphia, PA, United States; Division of Hematology, Children′s Hospital of Philadelphia, Department of Pediatics, University of Pennsylvania, Philadelphia, PA, United States ''.,      !8,=         !69   "                            878I89      !8      !,   !=              @*'           =′      !,   !=           @*'           '    !,      '4     !=       ''.,           -B  =95 /   1   "    .!8-,=&:/.!,-,;6:/ .!=-,5:& =&6==5BB/0      .!=                C      !8   !,         !8   !,       " "      S  @ "!@         !8           @*'    .!8@*'   1       =′           @*'                 )            !,       @*'    !8 3           !,   !=      1             !,   !=                           3                                          ''.                             ''.,   589 Efficient Generation and Amplification of HighCapacity Adeno-Associated Virus/Adenovirus Hybrid Vectors for the Stable Genetic Modification of Mammalian Cells Manuel A F V Gonỗalves,1 Ietje van der Velde-van Dijke,1 Josephine M Janssen,1 Bram T H Maassen,1 Evert H Heemskerk,1 Dirk-Jan E Opstelten,2 Shoshan Knaän-Shanzer,2 Maria G Pau,2 Dinko Valerio,1,2 Antoine A F de Vries.1 Section Gene Therapy, Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, Netherlands; 2Crucell B.V., Leiden, Netherlands                                    "      3    "     -''./             S192 Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy ...   "     583 A cis-Acting Element That Directs Exclusively Circular Adeno- Associated Virus Replication Sergei A Musatov, Jill Roberts, Donald Pfaff, Michael Kaplitt ''