1118 non invasive follow up of fluorescent reporter gene transfer into the skeletal muscle

1118 Non Invasive Follow Up of Fluorescent Reporter Gene Transfer into the Skeletal Muscle Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts Copyright © The American Society of Gene Therapy S[.]

  1116 Murine In Utero Gene Delivery by Intramuscular argeted and Untargeted High Capacity RGD-Targeted Injection of RGD-T Adenovirus Roberto Bilbao,1 Daniel P Reay,1 Tiffany H Fitzsimmons,1 Laura Goldberg,1 Volker Biermann,2 Stefan Kochanek,2 Paula R Clemens.1,3,4 Department of Neurology, University of Pittsburgh, Pittsburgh, PA, United States; 2Center for Molecular Medicine, University of Cologne, Cologne, Germany; 3Department of Molecular Genetics and Biochemistry, University of Pittsburgh, Pittsburgh, PA, United States; 4Neurology Service, Department of Veterans Affairs Medical Center, Pittsburgh, PA, United States -                             $       '      "                 -C"' /                                        3  @    C"'       ' ""' -@$/                                    @$                    8B    ->"8B/           C"'                                              C"'                              >"8B          -'&65     /    -*C= =  /     '@          @$"  C"'     C"'               #) '          5            -#./    ?          E             >"8B                    >        8:389;%    E                 -       /              G    β"  3     "  "β"$"   -)*!/   -       C"'                          '&65   C     @$    C"'        *C%= =                                3         E         C"'$             @$"   C"'                        3                      3        )      8/ C"'                                 ,/ @$"  C"'           C"'                   )                 @$      C"'                       C"'          1117 Adeno-Associated V irus V ector-Mediated Gene Virus Vector-Mediated Transfer into Dystrophin-Deficient Skeletal Muscles Evokes Enhanced Immune Responses Katsutoshi Yuasa,1 Miki Sakamoto,1 Yuko Miyagoe-Suzuki,1 Aki Tanouchi,1 Madoka Yoshimura,1 Hiroshi Yamamoto,2 Jane Li,3 Jeffrey S Chamberlain,4 Xiao Xiao,3 Shin′ichi Takeda.1 Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan; 2Department of Immunology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan; 3Department of Molecular Genetics and Biochemistry, Gene Therapy Center, and Duchenne Muscular Dystrophy Research Center, University of Pittsburgh, Pittsburgh, PA, United States; 4Department of Neurology, University of Washington School of Medicine, Seattle, WA, United States $       -$#$/   F"                .       86    $*' ' ''.   "    "   $*' Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy                  $#$        "  3                                 ''.      "            ''.       5    #.  -''."#.DN/                     &;2D%89 -289/     β"   -β"/ 3            6     E  D            $6"   $:"           β"" 3       ''.   "E           β"                  ''.   "E            289          ''.              ?            "$6    -A8&/    β" 3          6   "E                                          ''."#.DN        "     -'!/                           E   ''."#.DN        "  "      -.2'=V/                    ''.              .2'=V                 .2'=V                     "                1 3            '!          E     ''.        5          "  #A        β" 3         :          3          ,6    289                                       "    ''.                                          "  1118 Non-Invasive Follow-Up of Fluorescent Reporter ransfer into the Skeletal Muscle Transfer Gene T Daniel Stockholm,1 Anne-Marie Douar,1 Mathieu Taveau,1 Olivier Danos,1 Corinne Laplace-Builhe,1 Patrick Gonin.1 Genethon, Evry, France (          3           1             1                                                       3                                 "           $        1        3                   >?!   >+?!                                '   "  E       "     #.">+?!      +?!                         E  '     G                    1        (                   7 -/               -/   =$           -/           4       2               "  E    ''."#.">?!               C!D ?           ,     E  '              ?                       "           )                   S363        3    *                     3          6:9  &,9                 #                                                1                                                     1119 Comparison of a Series of Mini-Dystrophin Genes in Protection of Dystrophic Muscles in mdx Mice Bing Wang,1 Juan Li,1 Xiao Xiao.1 Dept of Molecular Genetics and Biochemistry, University of Pittsburgh, Pittsburgh, PA, United States $     -$#$/F"                                    $          G                         !                       -8%=/   "    1         "                     - & L B   /   ''.                                                        1        0       "    #A   ''.       8  &     ,           )         "           -@8@,@,, @,6/ , -C8 C6/               "        3                  C   "    =                            )        ''.        "      -   &  /             E              1120 Insertion of Adenovirus E4 Region ORF3 into a Helper-Dependent Fully Gutted Adenoviral V ector: Lack Vector: of Influence on Initial Level of Gene Expression and Long-T erm Expression in Muscle Long-Term Jatinderpal R Deol,1 Renald Gilbert,1 An-Bang Liu,2 Paul C Holland,1 Josephine Nalbantoglu,1 George Karpati.1 Neuromuscular Research, Montreal Neurological Institute, Montreal, Quebec, Canada; 2Department of Neurology, Tzu Chi Medical Center, Hualien, Taiwan $       -$#$/    G                   $#$                        "                     @                                 $#$                                       $*'  "   -8,/ C                       3     -C     8,7 8;68 ,998/ ?                  >6          =-)@?=/        3 -82      >6               "      ' 2$)@?=   '     >6        )@?=           >82    )@?=              3          1121 A T wo-Step Protocol for Gene T ransfer to Adult Two-Step Transfer Skeletal Muscle: Use of Adeno-Associated Virus Expressing the Coxsackie and Adenovirus Receptor (CAR) Josephine Nalbantoglu,1 Qinshang Teng,1 George Karpati,1 Paul C Holland.1 Montreal Neurological Institute/McGill University, Montreal, Quebec, Canada          -' /                            '@     G                α     '               '                         "   '@        "      3  '@       '@                      6"B                   3  '@    "                        '       '@ 3                  '                 '@ 3               '             "   -''./                '@ 3               '@ $*'   ''.        ''."'@              ,5=       ''."'@      3    '@        L 6B $      "'@          ''."'@                        '       ,8,          ''."'@   6:         ' #.N       -#)/  : 4   ,8,            ' #.N   #)        β"          ''."'@"                                   ' #.N   3          ''."'@                   - '/      3"       -M&/   E         8& 3 8989    ''."'@     'E       "    -!2(/ ?       '  E    ,8 3 8989     ' #.N     G  89    '  E                β"     ''."'@ E  '           β"      -&6; ± ,89/       !2("     -B; ± 88/ -!O 99&    "   V    " / >3     ''."'@"E                              3  β"   0        ''."'@       β"  " 3             E    ''."'@                   1  '     C                       >               E        "          '                       '              "  Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy