299 Detection of Spontaneous Schwannomas by MRI in a Transgenic Murine Model of Neurofibromatosis Type 2 Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts Copyright © The American Society of[.]
"8 "! " ! 5,&" ( $*' 3 !)# !)# " 1 " " - $*?/ -'.=9 ?'!" $*?/ >8 >=%>6 - $*?/ !$ $*? ?'! '.=9 ?'!" $*? E ( " $ E B")C$' >D(' 6B 8, $*? E '.=9 ?'!" $*? - $*? / '.=9 ?'!" $*? ;9H $' 69H 3 ) $*? " ?'! % $' E 299 Detection of Spontaneous Schwannomas by MRI in a T ransgenic Murine Model of Neurofibromatosis T ype Transgenic Type Shanta M Kumar,1 Yi Tang,2 Marco Giovannini,3 Rod T Bronson,4 Ralph Weissleder,2 Xandra O Breakefield.1 Neurology, Massachusetts General Hospital East, Charlestown, Massachusetts, United States; 2Molecular Imaging, Massachusetts General Hospital East, Charlestown, Massachusetts, United States; 33 Institut National de la Sante et de la Recherche Medicale (INSERM), U434-Institut Curie, Paris, France; 4Rodent Histopathology Core Facility, Harvard Medical School, Boston, Massachusetts, United States 298 Neurodegeneration Prevented by Adenoviral Vector Delivery of GDNF in a Rat Model of Parkinson Parkinson′′s Disease Tiina Paunio,1 Anh Do Thi,1 Paulette Saillour,1 Lucy Ferrero,2 JeanFrancois Dedieu,2 Jacques Mallet.1 LGN, CNRS UMR7091, Paris, France; 2Aventis Pharma Devlopment, Aventis, Vitry sur Seine, France ! V -!$/ G -$'/ D"$ - / C * E Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy ( -#@/ *?, 3 ( !) #@ ' 3 :&H -8,%86/ ,6 ( ,8H 86H ; H ;H 3 86H ;H IBBH-,%=/ # #@ ,8 H #@ "$ !' ? , 1 ? #@ C 3 ( ("899 .(." *?, ( 3 *?, ? #@ 1 ; H #@ 3 8 -C(./ @= N #@ 1 C(. P $ ' 4( ' @ # @ # ' \ $'#$8;" S99 "8 "! " ! 99"8"9&=; # C? # $ (#A -!&9"':B=&&/ ( ' -@,6" '5,;:,/ @0 300 Identification of Novel Stroke T argets Using Targets ™ Strategies SMARTOMICS™ SMARTOMICS Scott Ralph,1 Steven N Parham,1 Sheena Lee,1 David Krige,1 Rob D Barber,1 James W Connell,1 Sue M Kingsman,1 Nick D Mazarakis,1 Chris Mundy.1 Oxford Biomedica Ltd, Oxford Science Park, Oxford, United Kingdom ? G ! 3 3 3 G _( ™V" ( ™ 3 1 ->'./ 3 >'." C"8α >!'( 3 3 3 G 3 -C@> / G G 3 3 C@> 3 C"8α%>!'( ? 3 ' 3 301 AA VV ector-Mediated T ransduction in the Cat AAV Vector-Mediated Transduction Brain Charles H Vite,1,2 Marco A Passini,1,2 Aracelis Polesky,1,2 Patricia O′Donnell,1 Jean Zweigle,1 Anna Salvetti,3 Philippe Moullier,3 Mark E Haskins,1 John H Wolfe.1,2 School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, United States; 2Children′s Hospital of Philadelphia, Philadelphia, PA, United States; 3Laboratoire de Therapie Genique, Nantes, France ' -*(/ G ( ′ # 1 " ' *( ' " -''./ 3 " - 4(2/ 4(2 ''. 4(2 G C 3 899 3 8999 ''. G 3 4(2 G 3 S100 G '' 4(2 4(2 - CβC / CβC ''. 6& 3 898, % 3 #@ , D E G G 3 ''."CβC E E - 3 / - / :" " G 8: 3 G G > 4(2 3 " 4(2 ''. 2 ''. 302 Systemic Gene Delivery in Adult Mouse Brain by Adeno-Associated V iral V ectors Viral Vectors Lei Wang,1 Liqiao Zhou,2 Bing Wang,2 Zhong Wang,2 Juan Li,2 Xiao Xiao,2 Yan Xu.1,3 Departments of Anesthesiology; 2Molecular Genetics and Biochemistry; 3Pharmacology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States # $ 3 0 " ,- ''.,/ =- ''.=/ " $*' - ?!/ E 4 3 3 8" ' E 9," )$ - 3 = 3 898= / -(?/ ' & ,B =B E ?! 3 3 0 ?! 3 G -(.N/& E 3- "/ ,B =B E ) & 3 (.N E 3 ,B =B E * 3 ''., ''.= 3 1 (? ) ''., ''.= " *( 303 A Model System for Gene Therapy of Murine Mucopolysaccharidosis VII in the CNS Using an HSV-1 Vector Bradford K Berges,1 Nigel W Fraser.1 Microbiology, University of Pennsylvania, Philadelphia, PA, United States # -#!(/ G " - 4(2/ #!( 1 4(2 $*' #!( 3 4(2 1 4(2 Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy