511 Endogenous Gene Regulation with Polydactyl Zinc Finger Transcription Factors Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts Copyright © The American Society of Gene TherapyS168 ��!� ��[.]
! !"7"" " ! 509 A Simple Method for Inducing RNA Interference in Adult Mice Anton P McCaffrey,1 Leonard Muese,1 Douglas Conklin,2 Gregory Hannon,2 Mark A Kay.1 Pediatrics and Genetics, Stanford University School of Medicine, Stanford, CA, United States; 2Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, United States @*' -@*'/ @*' @*' @*' " @*' @*' -@*'/ @* @*'" 3 @*' @*' ,8 @*' @*' ' @*' - B / E @*' - @*'/ ' @*' @*' -@*'/ @*' " D=" 3 "8 -'' /D 1 D @*' @*' 88 3 :8 H -J%" ,, H/ ;, >D(' '' ( @*' @*' 3 5B; H -J%" 88 H/ @*' 8, 3 @*' ' @*' 3 510 Inducible Regulation of VEGF by Artificial Transcription Factors YaLi Lee, S Kaye Spratt, Lei Zhang, Carolyn L Dent . -.>?/ G >? ) 3 3 S168 >? 3 " >? G 3 $*' ) .>? 3 G $*' 1 >? B& 3 3 % % I 3 ? 3 G "@ 3 3 - / % ( ( C>A ,5= 3 G G $*'" " B& >? B& 3 3 3 51 Endogenous Gene Regulation with Polydactyl 511 ranscription Factors Transcription Zinc Finger T David J Segal,1 Carlos F Barbas III.1 Molecular Biology, The Scripps Research Institute, La Jolla, CA, United States 2 $*'" G $*'" 3 @ " 3 ' " 1 * G G 1 $ G $*'" 1 G " G 899 G" %$*' ( 1 G 4 G G !@ 1 3 ! " 3 ! 3 G G 8: $*' 1 1 " " " ' 3 " 2", 2"= 8: > 3 Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy ! !"7"" " ! " E " G 512 Ecdysone Receptor-Based Inducible Gene Regulation Systems for Simultaneous Regulation of T wo Two Genes Subba R Palli, Masha Kapitskaya, Mohan Kumar, Prasanna Kumar, Peter White, Henry Hoff III, Dean E Cress ->@/ G F -@F@/ 3 >@" >@" 1 >@ @F@ *C= = C) >@ " @F@ " ' >@ @F@ 9, # " (™"> #3 ,99 # (™"> >@ ->@/ " (™d> -!'/ # ' # >@ " >@ $ >@ -$>@/ " ' >@-$>?/ D 3'$*' $>@-$>?/ 'D6$*' C@F@"D@F@->?/ !8B &F'D@>(>'! - &F 'D6 ' ''/ :9!D4 - D 3' ' ''/ *C= = *C= = 3 " (™"> !' ' (™"> (>'! ) !' (>'! ' (™"> !' (>'! >@ 3 Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy 513 In Vivo Selection with a Regulated Cell Growth Switch Allows for a Selective Increase in the Fraction of Erythrocytes Expressing a Linked Gamma-Globin Cassette Following Bone Marrow T ransduction in Mice Transduction David W Emery,1 Julie Tubb,1 Yumiko Nishino,1 Tamon Nishino,1 Kevin G Otto,1 George Stamatoyannopoulos,1 C Anthony Blau.1 Department of Medicine, University of Washington, Seattle, WA, United States 3 3 #(." 3 >?! -?=B./ G -$/ '!,98:; -* ,B7B6 ,999/ " 3 -C 897:;; 8555/ ( B $" 3 3 >?! &;H 5BH " ;H::H - M8:/ ' : $ E 8, 6 = -@2/ 3 ?! " $ 3 6 2 $ @2 3 ?! =6" ,&±8,H ;,±,,H -O9998/ @2 3 " 58" 8B±8=H:9±=;H-O9998/' 1 ;" $ @2 3 ?! " ?!" 3 02 8B" - =9±89H6;±8:HM999,/ 6 ' -8B 6 $/ @2 02 3 ?! " @2 3 " =," - =,±,,H M998 " / -M5/ 3 ( $*' $" -,&±95 8&±8, M996/ 5" @2 3 " C @2 3 " 89" 3 >?! ? 3 514 T ranscript Profiling of Adenovirally T ransduced Transcript Transduced Hearts Indicates a Robust InterferonInterferon-γγ-Dependent Immune Response Stuart A Cook,1 Youngkeun Ahn,1 Takashi Matsui,1 Anthony Rosenzweig.1 CVRC, Massachussettes General Hospital, Charlestown, MA, United States 7 $ E & -' / C ' " -/ 3 G 3 ' # 7 @ ' β" ' - "'/ '-'"''/ ,5= 3 , -:9μ 9& 3 898, %/ S169 ... 3 510 Inducible Regulation of VEGF by Artificial Transcription Factors YaLi Lee, S Kaye Spratt, Lei Zhang, Carolyn L Dent .