THÔNG TIN TÀI LIỆU
Ngày đăng: 08/11/2022, 15:01
Xem thêm:
Mục lục
CH25H upregulation in CCALD patient-derived cells
ABCD1-dependent regulation of CH25H mRNA expression
Microglial recruitment and IL-1beta production by 25-HC
NLRP3 inflammasome assembly and activation by 25-HC
Figure™2ABCD1 regulates the induction of CH25H expression in a VLCFA-dependent manner.(a,b) Cellular levels of VLCFA (a) and mRNA levels of™CH25H (b) in control fibroblasts untransfected or transfected with scrambled- or ABCD1-targeting siRNA (ABCD1 KD) a
Molecular mechanism of NLRP3 activation by 25-HC
Figure™325-HC induces microglial recruitment and IL-1beta production.(a) Illustration of stereotaxic injection of 25-HC (100thinspmgrM) or vehicle (0.1percnt ethanol in PBS) into the corpus callosum of mouse brain. (b) Representative immunofluorescence im
Figure™425-HC promotes the assembly and activation of the NLRP3 inflammasome.(a) Immunoblots of culture supernatants from mouse BMDMs and microglia untreated or treated with 25-HC (10thinsph) in the presence of LPS (last 4thinsph). (b) Immunoblots from BM
NLRP3 deficiency reduces cerebral inflammation by 25-HC
Figure™525-HC activates the NLRP3 inflammasome signalling in a potassium effluxsolmitochondrial ROSsolLXR-dependent manner.(a)™Immunoblots of mouse BMDMs treated with 25-HC (50thinspmgrM, 10thinsph) and LPS (final 4thinsph) in the presence of glibenclamid
TÀI LIỆU CÙNG NGƯỜI DÙNG
TÀI LIỆU LIÊN QUAN