ISSN 1323–8930 Allergology International JAPANESE SOCIETY OF ALLERGOLOGY Editor-in-Chief Takeshi Fukuda Vol 51 2002 Allergology International Aims and Scope EDITOR-IN-CHIEF Takeshi FUKUDA Tochigi EDITORIAL BOARD Kazuo AKIYAMA Xaver BAUR Jean BOUSQUET Junichi CHIHARA Jan E DE VRIES Stephen J GALLI Gerald J GLEICH Stephen T HOLGATE Chein-Soo HONG Akira ISHII Itsuo IWAMOTO Naomi KONDO Tak H LEE Hiroichi NAGAI Kiyoshi NISHIOKA Romain PAUWELS TAE PLATTS-MILLS Chisei RA Johannes RING Sergio ROMAGNANI Wan Cheng TAN Masaru TANIGUCHI Montri TUCHINDA Kazuhiko YAMAMOTO Kohei YAMAUCHI Yukiyoshi YANAGIHARA Kanagawa Hamburg Montpellier Akita Vienna Stanford Rochester Southampton Seoul Tochigi Chiba Gifu London Gifu Tokyo Ghent Charlottesville Tokyo Munich Florence Singapore Chiba Bangkok Tokyo Iwate Kanagawa ADVISORY COMMITTEE K Frank AUSTEN John BIENENSTOCK Alain DE WECK Leonardo M FABBRI Kimishige ISHIZAKA SGO JOHANSSON AB KAY Tadamitsu KISHIMOTO Lawrence M LICHTENSTEIN Francois BM MICHEL Minoru OKUDA Mario RICCI Albert L SHEFFER Reuben SIRAGANIAN Robert G TOWNLEY Boston Hamilton Bern Ferrara Yamagata Stockholm London Osaka Baltimore Montpellier Tokyo Florence Boston Bethesda Omaha Allergology International is the official English language journal of the Japanese Society of Allergology, publishing peer-reviewed articles of scientific excellence in human and experimental allergology and related fields of research The journal aims to further the international exchange of results and encourages authors from all countries to submit papers in the following categories: ‘Original articles’, ‘Case reports’, ‘Short communications’, ‘Occasional reviews’, ‘Editorials’ and ‘Letters to the Editor’ All articles are peer-reviewed by at least two researchers expert in the field of the submitted paper Allergology International is supported by a Grant-in-Aid for Publication of Scientific Research Results from the Japan Society of the Promotion of Science Abstracting and Indexing Services The journal is indexed by BIOSIS Database, Chemical Abstracts Service, Ipharma, Reactions Weekly, University Microfilms and Nasal-Allergy Information Center Editorial Correspondence All material for publication should be submitted to Professor Takeshi Fukuda, Editor-in-Chief, Allergology International, Japanese Society of Allergology, Ishimizu Building 7F, 1-35-26 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan For detailed instructions concerning the submission of manuscripts, please refer to the Instructions for Authors at the back of a recent issue of the journal or visit the journal web page Business Correspondence and Advertisement Booking All matters relating to orders, subscriptions, back issues, offprints, general enquiries and advertisement bookings should be addressed to: Blackwell Science Asia Pty Ltd, PO Box 378, Carlton, Victoria 3053, Australia (tel: (+61) 9347 0300; fax: (+61) 9347 5001; email: www.blackwellscience.com/ain) Blackwell Science Asia’s Tokyo office has Japanese speakers available to answer queries on tel.: 03 5802 6781; fax: 03 5802 6782 (For international calls, the country code for Japan is 81.) Subscription Rates The journal is published four times per year and the prices for 2002 are as follows: Institution: ¥40 600 (Japan); US$350 (rest of world) Personal: US$120 (rest of world) For online subscription prices please contact subs@blacksciasia.com.au The journal is despatched by surface air-lifted delivery Copyright and Photocopying © 2002 The Japanese Society of Allergology Authorization to photocopy items for internal or personal use, or the internal or personal use of specific clients, is granted by Blackwell Science Asia Pty Ltd for libraries and other users registered with the Copyright Clearance Center (CCC) Transactional Reporting Service provided that the base fee of US$15.00 per copy is paid directly to: CCC, 222 Rosewood Drive, Danvers, MA 01923, USA This consent does not extend to other kinds of copying, such as copying for general distribution, for advertising or promotional purposes, for creating new collective works or for resale Special requests should be addressed to the publisher ISSN: 1323-8930/2001 US$15 Disclaimer The Publisher, the Society and the Editors cannot be held responsible for errors or any consequences arising from the use of information contained in this journal; the views and opinions expressed not necessarily reflect those of the Publisher, the Society or the Editors, neither does the publication of advertisements constitute any endorsement by the Publisher, the Society or the Editors of the products advertised Blackwell Journals Online Allergology International is also available online via Blackwell Synergy Fulltext online articles include reference links to cited articles and external databases, and a full search facility so that you can find the information you are looking for Keep up to date with the latest tables of contents, emailed directly to your desktop, by registering for free at www.blackwell-synergy.com This journal is printed on acid-free paper Production Editor: Natalie Korszniak (email: Natalie.Korszniak@blacksci-asia.com.au) Visit the Journal website at: www.blackwell-science.com/ain CONTENTS Volume 51: 1, March 2002 REVIEW ARTICLE Clinical lung transplantation in Japan: Current status and future trends Yuji Matsumura, Yoshinori Okada, Kazuyoshi Shimada, Tetsu Sado and Takashi Kondo ORIGINAL ARTICLES Influence of local antigen exposure dose in the upper respiratory tract on sensitization with cedar pollen Kazuo Sakurai, Kensei Naito, George Ishii, Tamotsu Ogawa, Kenji Takeuchi, Sho Miyata and Ren Baba Inhalant corticosteroids inhibit mechanical strain-induced RANTES and eotaxin production by human airway smooth muscle cells Shu Hashimoto, Shuichiro Maruoka, Yasuhiro Gon, Ken Matsumoto and Takashi Horie Attenuation of allergic airway inflammation and associated pulmonary functions by mycobacterial antigens is independent of IgE in a mouse model of asthma Michael T Hopfenspirger, Sharidan K Parr, Robert G Townley and Devendra K Agrawal Serum levels of soluble CD30 and total IgE in alcoholics Arturo González-Quintela, Maria-Jesus Domínguez-Santalla, Luis-Fernando Pérez, Santiago Lojo and Carmen Vidal Inverse association between daily activity and sleep activity and related factors in elderly patients with chronic obstructive pulmonary disease and bronchial asthma Kozui Kida, Tomoko Oozeki and Hideki Katsura Exhaled nitric oxide as a marker of atopic asthma Kaj Korhonen, Minna Purokivi, Anne Kotaniemi-Syrjänen, Tiina M Reijonen, Mikko Vahteristo and Matti Korppi CASE REPORT Lack of effect of bone marrow transplantation on airway hyperresponsiveness in an asthmatic Kunihiko Iizuka, Tohru Sakura, Akihiro Yoshii, Shuichi Miyawaki, Tetsunari Oyama, Kunio Dobashi, Tsugio Nakazawa and Masatomo Mori Contents Japanese Journal of Allergology Volume 50, Issues and 11 13 21 33 39 47 51 61 Volume 51: 2, June 2002 REVIEW ARTICLES Immunomodulation in the treatment and/or prevention of bronchial asthma Robert G Townley, Russell J Hopp, Devendra K Agrawal, Thomas B Casale and Michael T Hopfenspirger 63 iv CONTENTS Early treatment in asthma: How early is early? Tari Haahtela ORIGINAL ARTICLES Effect of short-course steroid treatment for airway inflammation in patients with asthma Yasuo To, Takeshi Koshino, Masako To, Koichiro Kudo, Yasuyuki Sano and Koji Ito Study of 456 cases of death from asthma (1993–1997) from an investigation by the Tokyo Medical Examiner’s Office Taeru Kitabayashi, Yoji Iikura and Shogo Tokutome Peak expiratory flow in normal healthy Japanese adults: Comparisons with values reported in other races Kazuharu Tsukioka, Sohei Makino, Terumasa Miyamoto, Naohito Tanabe and Kohei Akazawa Anti-endothelial cell IgE antibodies in children with bronchial asthma Waka Harada, Shin-ichi Toyabe and Makoto Uchiyama Anaphylaxis caused by the ingestion of cultivated mushroom (Agaricus bisporus): Identification of allergen as mannitol Venkatesh L Hegde, Jharna R Das and Yeldur P Venkatesh Methacholine, cold air and exercise challenge tests in the diagnosis of bronchial responsiveness at school age: A follow-up study from birth to school age Kari Nikolajev, Matti Korppi, Heikki Koskela, Kyllikki Remes, Veikko Jokela, Esko Länsimies and Kirsti Heinonen Risk factors for asthma and allergic diseases among 13–14-year-old schoolchildren in Japan Takako Sugiyama, Kumiya Sugiyama, Masao Toda, Tastuo Yukawa, Sohei Makino and Takeshi Fukuda Contents Japanese Journal of Allergology Volume 50, Issue 12, Volume 51, Issue 75 85 93 101 113 121 131 139 151 Volume 51: 3, September 2002 REVIEW ARTICLES Current and potential improvements in the treatment of asthma from increased understanding of airway pathophysiology Kian Fan Chung T cell signaling: Protein kinase C θ , the immunological synapse and characterization of SLAT, a novel T helper 2-specific adapter protein Yoshihiko Tanaka and Amnon Altman ORIGINAL ARTICLES Recombinant soluble form of the high-affinity IgE receptor α subunit and anti-IgE antibody inhibit IgE synthesis by IgE-expressing B cells through distinct pathways Keiichi Kajiwara, Chisei Ra and Yukiyoshi Yanagihara Perioperative corticosteroids for intermittent and mild persistent asthma Hiroto Matsuse, Terufumi Shimoda, Ikuko Machida, Yuki Kondo, Tetsuya Kawano, Sachiko Saeki, Shinya Tomari, Kazuko Mitsuta, Chizu Fukushima, Yasushi Obase and Shigeru Kohno 153 167 175 185 CONTENTS Immunologic determination of the major allergen, Cry j 1, in Cryptomeria japonica pollen of 117 clones in Toyama prefecture: Some implications for further forestry research in pollinosis prevention Maki Saito and Hidetoyo Teranishi Role of protein kinase A in the inhibition of human mast cell histamine release by β-adrenergic receptor agonists Toshinobu Kato, Masahiro Kimata, Toshikazu Tsuji, Michitaka Shichijo, Masayuki Murata, Toru Miura, Isao Serizawa, Naoki Inagaki and Hiroichi Nagai v 191 197 SHORT COMMUNICATION Study of food allergy among university students in Japan Keiichiro Yoneyama and Akemi Ono 205 Contents Japanese Journal of Allergology Volume 51, Number Notices 209 211 Volume 51: 4, December 2002 REVIEW ARTICLE Genetic and environmental factors of atopy Akiko Otsu and Taro Shirakawa 213 Allergen immunotherapy: Current and new therapeutic strategies Jennifer M Rolland and Robyn E O’Hehir 221 ORIGINAL ARTICLES Evaluation of two grass pollen extracts for immunotherapy by serum determinations of specific IgE and IgG4 antibodies towards purified Timothy grass pollen allergens (Phl p 1, 2, 4, 5, 6, 7, 11, 12) in patients undergoing hyposensitization treatment Renato Enzo Rossi, Giorgio Monasterolo, Antonio Diana, Serena Monasterolo and Maurizio Delucchi Questionnaire-based characterization of bronchial asthma in the elderly: Analysis in Niigata Prefecture, Japan Eiichi Suzuki, Takashi Hasegawa, Toshiyuki Koya, Ichiro Mashima, Yoshiyuki Muramatsu, Ariyoshi Kondo, Masaaki Arakawa and Fumitake Gejyo 233 241 Contents Japanese Journal of Allergology Volume 51, Number 249 Acknowledgments 251 Author index 253 Subject index 255 ... COMMUNICATION Study of food allergy among university students in Japan Keiichiro Yoneyama and Akemi Ono 205 Contents Japanese Journal of Allergology Volume 51, Number Notices 209 211 Volume 51: 4, December... Masatomo Mori Contents Japanese Journal of Allergology Volume 50, Issues and 11 13 21 33 39 47 51 61 Volume 51: 2, June 2002 REVIEW ARTICLES Immunomodulation in the treatment and/or prevention of bronchial... Ariyoshi Kondo, Masaaki Arakawa and Fumitake Gejyo 233 241 Contents Japanese Journal of Allergology Volume 51, Number 249 Acknowledgments 251 Author index 253 Subject index 255