Blood Cell – An Overview of Studies in Hematology pptx

BLOOD CELL – AN OVERVIEW OF STUDIES IN HEMATOLOGY Edited by Terry E. Moschandreou Blood Cell – An Overview of Studies in Hematology http://dx.doi.org/10.5772/2979 Edited by Terry E. Moschandreou Contributors Gökhan Cüce, Tahsin Murad Aktan, Mahmoud Rafea, Serhiy Souchelnytskyi, Filip Cristiana, Zamosteanu Nina, Albu Elena, Ambreen Shaikh, Deepa Bhartiya, Moneer Faraj, Nihaya Salem, Junko Takahashi, Akiko Takatsu, Masaki Misawa, Hitoshi Iwahashi, Osamu Hayashi, Karen A. Selz, Terry E. Moschandreou, Youngchan Kim, Kyoohyun Kim, YongKeun Park, Hisham Mohamed, A.B. Shrivastav, K.P. Singh, S. Druyan, Kikuji Yamashita, Clement E. Zeh, Collins O. Odhiambo, Lisa A. Mills, Nuri Mamak, İsmail Aytekin Published by InTech Janeza Trdine 9, 51000 Rijeka, Croatia Copyright © 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license, which allows users to download, copy and build upon published articles even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech, authors have the right to republish it, in whole or part, in any publication of which they are the author, and to make other personal use of the work. Any republication, referencing or personal use of the work must explicitly identify the original source. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials, instructions, methods or ideas contained in the book. Publishing Process Manager Sandra Bakic Typesetting InTech Prepress, Novi Sad Cover InTech Design Team First published September, 2012 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechopen.com Blood Cell – An Overview of Studies in Hematology, Edited by Terry E. Moschandreou p. cm. ISBN 978-953-51-0753-8 Contents Preface IX Section 1 Main Concepts 1 Chapter 1 Platelets 3 Gökhan Cüce and Tahsin Murad Aktan Chapter 2 Rediscovering Red Blood Cells: Revealing Their Dynamic Antigens Store and Its Role in Health and Disease 13 Mahmoud Rafea and Serhiy Souchelnytskyi Chapter 3 Homocysteine in Red Blood Cells Metabolism – Pharmacological Approaches 31 Filip Cristiana, Zamosteanu Nina and Albu Elena Chapter 4 Pluripotent Stem Cells in Bone Marrow and Cord Blood 69 Ambreen Shaikh and Deepa Bhartiya Chapter 5 C-Reactive Protein 89 Moneer Faraj and Nihaya Salem Chapter 6 Whole Blood RNA Analysis, Aging and Disease 101 Junko Takahashi, Akiko Takatsu, Masaki Misawa and Hitoshi Iwahashi Chapter 7 Proliferation and Differentiation of Hematopoietic Cells and Preservation of Immune Functions 119 Osamu Hayashi Chapter 8 Spontaneous Alternation Behavior in Human Neutrophils 147 Karen A. Selz Chapter 9 RBC-ATP Theory of Regulation for Tissue Oxygenation-ATP Concentration Model 155 Terry E. Moschandreou VI Contents Section 2 Measurement of RBC Deformability and Microfluidics Technology for Cell Separation 165 Chapter 10 Measurement Techniques for Red Blood Cell Deformability: Recent Advances 167 Youngchan Kim, Kyoohyun Kim and YongKeun Park Chapter 11 Use of Microfluidic Technology for Cell Separation 195 Hisham Mohamed Section 3 Applications in Haematology 227 Chapter 12 Tigers Blood: Haematological and Biochemical Studies 229 A.B. Shrivastav and K.P. Singh Chapter 13 Ascites Syndrome in Broiler Chickens – A Physiological Syndrome Affected by Red Blood Cell 243 S. Druyan Chapter 14 The Effects of the Far-Infrared Ray (FIR) Energy Radiation on Living Body 271 Kikuji Yamashita Chapter 15 Laboratory Reference Intervals in Africa 303 Clement E. Zeh, Collins O. Odhiambo and Lisa A. Mills Chapter 16 Principles of Blood Transfusion 321 Nuri Mamak and İsmail Aytekin Preface The editor has incorporated scientific contributions from a diverse group of leading researchers in the field of hematology and related blood cell research. This book aims to provide an overview of current knowledge pertaining to our understanding of hematology. The main subject areas will include blood cell morphology and function, the pathophysiology and genetics of hematological disorders and malignancies, blood testing and typing, and the processes governing hematopoiesis. Blood cell physiology, biochemistry and blood flow are covered in this book. This text is designed for hematologists, pathologists and laboratory staff in training and in practice. Topics include platelets, whole blood RNA analysis, C-reactive protein, pluripotent stem cells, proliferation and differentiation of hematopoietic cells, homocysteine in red blood cells metabolism: pharmacological approaches, measurement techniques for red blood cells deformability, spontaneous alternation behaviour in human neutrophils, microfluidics technology for cell separation, effects of far infrared radiation on living body, laboratory reference intervals in Africa, RBC-ATP biochemistry and modelling, dynamics of RBC and antigens, transfusion principles, haematological and biochemical studies in tigers and ascites syndrome in broiler chickens. The work presented in this book will be of benefit to medical students and to researchers of hematology and blood flow in the microcirculation. This book is written primarily for those who have some knowledge of chemistry, biochemistry and general hematology. The authors of each section bring a strong clinical emphasis to the book. I am greatly indebted to many individuals who helped in the preparation of this book. Those whom I wish especially to thank for their help with this edition include Drs. Dan Goldman and Khoa Nguyen. I am also indebted to Dr. Jiandi Wan, who gave permission to use the referenced figure in the chapter contributed by the editor. I also would like to thank all those who took the time to email me offering helpful criticisms and suggestions. This includes Ms. Sandra Bakic, publishing process manager at InTech. Dr. Terry E. Moschandreou University of Western Ontario, Middlesex College, London, Ontario, Canada . BLOOD CELL – AN OVERVIEW OF STUDIES IN HEMATOLOGY Edited by Terry E. Moschandreou Blood Cell – An Overview of Studies in Hematology. long thin branch like extensions at the blood circulating site of blood vessels of Blood Cell – An Overview of Studies in Hematology 4 bone marrow and