The differential diagnosis is broad Table 100.14 lists some of the more common forms of glomerular disease in the pediatric population TABLE 100.14 GLOMERULAR DISEASES IN CHILDHOOD Primary IgA nephropathy Goodpasture syndrome (Antiglomerular basement membrane disease) Idiopathic crescentic glomerulonephritis Membranoproliferative glomerulonephritis Membranous glomerulonephritis Secondary Henoch–Schönlein purpura Hemolytic uremic syndrome Goodpasture syndrome Microscopic polyarteritis Systemic lupus erythematosus Granulomatosis with polyangiitis Infectious Poststreptococcal glomerulonephritis Hepatitis B and C–associated nephritis Shunt nephritis Subacute bacterial endocarditis Inherited Alport syndrome Benign familial hematuria Thin basement membrane disease Hemolytic Uremic Syndrome Goals of Treatment The goals of treatment include hydration, supportive care, and managing the consequences of microvascular endothelial cell injury in affected organs Fluid balance, electrolyte abnormalities, and severe anemia may necessitate medical management and possible RRT Pancreatic and hepatic