in children with stroke, may also contribute to ischemic damage and should be controlled with antipyretics TABLE 97.6 STUDIES TO CONSIDER IN THE EVALUATION OF THE CHILD WITH ACUTE STROKE Brain imaging Computed tomography (noncontrast) Magnetic resonance imaging Angiography (standard or magnetic resonance) Cardiac Electrocardiogram Echocardiogram Hematologic Complete blood cell count Prothrombin and partial thromboplastin times Fibrinogen Erythrocyte sedimentation rate Hemoglobin electrophoresis Protein C and S quantification Antithrombin III level Chemistry Blood urea nitrogen Cholesterol and triglycerides Hepatic transaminases Serum amino acids Urine organic acids Toxicology screen Lactate Lumbar puncture In consultation with a pediatric hematologist, anticoagulation therapy should be strongly considered, once hemorrhagic stroke is excluded Current pediatric guidelines recommend the use of aspirin, low–molecular-weight heparin, or