Pediatric emergency medicine trisk 3051 3051

thiosulfate (2.5–5 mL/min of 25% solution) IV over 10–30 min, or IV push in cardiac arrest Children: (Na nitrite should not exceed recommended dose because dangerous methemoglobinemia may result): Hemoglobin Initial dose 3% Initial dose 25% Na nitrite Na thiosulfate IV (mL/kg) 8g 0.22 mL/kg (6.6 mg/kg) 0.27 mL/kg (8.7 mg/kg) 0.33 mL/kg (10 mg/kg) 10 g 12 g (normal) 14 g Cyanide— hydroxocobalamin (preferred) Digitalis Fluoride Heavy metals 1.10 1.35 1.65 0.39 mL/kg (11.6 1.95 mg/kg) Adult : g IV; Child: 70 mg/kg IV over 30 or IV push in cardiac arrest Fab antibodies (Digibind): Dose based on amount ingested and/or digoxin level (see text, package insert) Calcium gluconate 10%, 0.6 mL/kg IV slowly until symptoms abate, serum calcium normalizes; repeat PRN while monitoring serum calcium BAL (British Anti-Lewisite; dimercaprol): 300–450 mg/m2 /day (18–24 mg/kg/day) deep IM in divided doses for 3–5 days a (Arsenic, Mercury, Lead ) CaNa 2EDTA (ethylenediaminetetraacetic acid): 1,000–1,500 mg/m2 /day (25–75 mg/kg/day) continuous IV infusion or in 2–4 divided doses for up to days; see text for further details (Lead ) DMSA (succimer): 350 mg/m2 (10 mg/kg) PO every hrs for days, followed by 350 mg/m2 (10 mg/kg)