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Pediatric emergency medicine trisk 3097 3097

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FIGURE 102.5 Algorithmic approach to a toddler having ingested one to two doses (1 to pills or 5- to 10-cc swallow) of a drug a Medications notorious for their ability to have delayed onset in toxicity, beyond to hours, include oral hypoglycemic agents, sustained-release preparations, monoamine oxidase inhibitors, drugs taken concomitantly with anticholinergic agents, and acetaminophen In any patient with coma and an unexplained osmolal gap (the difference between calculated and observed osmolarity), a toxic alcohol should be strongly considered The presence of ketonuria in conjunction with the absence of metabolic acidosis effectively makes the diagnosis of isopropyl intoxication Isopropyl alcohol is easily removed by hemodialysis However, hemodialysis is rarely necessary because life-threatening toxicity does not occur until serum

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