2016;112:11–22.e2 Long S, Eldridge B, Harris SR, Cheung M Challenges in trying to implement an early intervention program for infants with congenital heart disease Pediatr Phys Ther 2015;27:38– 43 Malkar MB, Jadcherla S Neuro-motor mechanisms of pharyngo-esophageal motility in dysphagic infants with congenital heart disease Pediatr Res 2014;76:190–196 Stieber NA, Gilmour S, Morra A, et al Feasibility of improving the motor development of toddlers with congenital heart defects using a home-based intervention Pediatr Cardiol 2012;33:521–532 Wernovsky G, Licht D Neurodevelopmental outcomes in children with congenital heart disease – what can we impact? Pediatr Crit Care Med 2016;17(suppl 1):s232–s242 Mahle WT, Tavani F, Zimmerman RA, et al The assessment of neurologic injury before and after congenital heart surgery using magnetic resonance imaging Circulation 2002;106(suppl 1):I-109–I-114 10 Licht DJ, Shera DM, Clancy RR, et al Brain maturation is delayed in infants with complex congenital heart defects J Thorac Cardiovasc Surg 2009;137:529–536 11 Miller SP, McQuillen PS Neurology of congenital heart disease: insight from brain imaging Arch Dis Child Fetal Neonatal Ed 2007;92:F435–F437 12 Block AJ, McQuillen PS, Chau V, et al Clinically silent preoperative brain injuries do not worsen with surgery in neonates with congenital heart disease J Thorac Cardiovasc Surg 2010;140:550–557 13 Donofrio MT, Bremer YA, Schieken RM, et al Autoregulation of cerebral blood flow in fetus with congenital heart disease: the brain sparing effect Pediatr Cardiol 2003;24:436–443 14 Kaltman JR, Di H, Tian Z, Rychik J Impact of congenital heart disease on cerebrovascular blood flow dynamics in the fetus Ultrasound Obstet Gynecol 2005;25:32–36 15 Limperopoulos C, Tworetzky W, McElhinney DB, et al Brain volume and metabolism in fetuses with congenital heart disease: evaluation with quantitative magnetic resonance imaging and spectroscopy Circulation 2010;121:26–33 16 Sun L, Macgowan CK, Sled JG, et al Reduced fetal cerebral oxygen consumption is associated with smaller brain size in fetuses with congenital heart disease Circulation 2015;131:1313–1323 17 Glauser TA, Rorke LB, Weinberg PM, Clancy RR Congenital brain anomalies associated with the hypoplastic left heart syndrome Pediatrics 1990;85:984–990 18 Li Y, Klena NT, Gabriel GC, et al Global genetic analysis in mice unveils central role for cilia in congenital heart disease Nature 2015;521:520– 524 19 Licht DJ, Wang J, Silvestre DW, et al Preoperative cerebral blood flow is diminished in neonates with severe congenital heart defects J Thorac Cardiovasc Surg 2004;128:841–849 20 Lynch JM, Buckley EM, Schwab PJ, et al Time to surgery and preoperative cerebral hemodynamics predict postoperative white matter injury in neonates with hypoplastic left heart syndrome J Thorac Cardiovasc Surg 2014;148:2181–2188 21 Lim JM, Kingdon T, Saini B, et al Cerebral oxygen delivery is reduced in newborns with congenital heart disease J Thorac Cardiovasc Surg 2016;125:1095–1103 22 Prsa M, Sun L, van Amerom J, et al Reference ranges of blood flow in the major vessels of the normal human fetal circulation at term by phasecontrast magnetic resonance imaging Circ Cardiovasc Imaging 2014;7:663–670 ... Glauser TA, Rorke LB, Weinberg PM, Clancy RR Congenital brain anomalies associated with the hypoplastic left heart syndrome Pediatrics 1990;85:984–990 18 Li Y, Klena NT, Gabriel GC, et al Global genetic analysis in mice unveils central role for cilia in