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embolization is still currently applied, the studies by Portsmann and Rashkind form the foundation for all the interventional approaches currently used Galal MO, Hussain A, Arfi AM Do we need the surgeon to close the persistently patent arterial duct? Cardiol Young 2006;16:522–536 An excellent review of contemporary interventional techniques in transcatheter management of the patent arterial duct Friedman WF Studies of the response of the ductus arteriosus Heymann MA, Rudolph AM The Ductus Arteriosus Proceedings of the SeventyFifth Ross Conference on Pediatric Research 1978:35–43 [Columbus, OH] Gersony WM, Peckham GJ, Ellison RC, Miettinen OS, Nadas AS Effects of indomethacin on premature infants with patent ductus arteriosus: results of a national collaborative study J Pediatr 1983;102:895–906 These two reports review the humeral control mechanism of ductal patency and closure and document the application of that understanding to management of the premature with a clinically significant ductal patency Liebowitz M, Clyman RI Prophylactic indomethacin compared with delayed conservative management of the patent ductus arteriosus in extremely preterm infants: effects on neonatal outcomes J Pediatr 2017;187:119– 126 Sung SI, Chang YS, Chun JY, et al Mandatory closure versus nonintervention for patent ductus arteriosus in very preterm infants J Pediatr 2016;177:66–71 Malviya MN, Ohlsson A, Shah SS Surgical versus medical treatment with cyclooxygenase inhibitors for symptomatic patent ductus arteriosus in preterm infants Cochrane Database Syst Rev 2013;(3) [CD003951] These three studies highlight changes in practice regarding treatment (or nontreatment) options and outcomes in the management of the duct in the premature newborn Roberts P, Adwani S, Archer N, Wilson N Catheter closure of the arterial duct in preterm infants Arch Dis Child Fetal Neonatal Ed 2007;92:F248–F250 Thukaram R, Suarez WA, Sundararaghavan S Transcatheter closure of the patent arterial duct using the flipper coil in a premature infant weighing 1,400 g: A case report Catheter Cardiovasc Interv 2005;66:18–20 Sathanandam S, Justino H, Waller BR 3rd, Radtke W, Qureshi AM Initial clinical experience with the medtronic micro vascular Plug™ in transcatheter occlusion of PDAs in extremely premature infants Catheter Cardiovasc Interv 2017;89:1051–1058 Francis E, Singhi AK, Lakshmivenkateshaiah S, Kumar RK Transcatheter occlusion of patent ductus arteriosus in pre-term infants JACC Cardiovasc Interv 2010;3:550–555 Bentham J, Meur S, Hudsmith L, Archer N, Wilson N Echocardiographically guided catheter closure of arterial ducts in small preterm infants on the neonatal intensive care unit Catheter Cardiovasc Interv 2011;77:409–415 Morville P, Akhavi A Transcatheter closure of hemodynamic significant patent ductus arteriosus in 32 premature infants by amplatzer ductal occluder additional size-ADO II AS Cathet Cardiovasc Interv 2017 Zahn EM, Peck D, Phillips A, et al Transcatheter closure of patent ductus arteriosus in extremely premature newborns: early results and midterm follow-up Cardiovasc Interv 2016;9:2429– 2437 These studies established the feasibility and safety of ductal occlusion in the very low birth weight newborn
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