Andersons pediatric cardiology 1690

62 Cardio-oncology Thomas D Ryan Abstract Over the past several decades there have been significant improvements in the care of patients diagnosed with cancer One unintended consequence of the successes of therapy is a growing population of patients at risk for cancer treatment–related cardiotoxicity (CTC) Many chemotherapeutic agents lead to a wide variety of cardiovascular pathologies that can manifest within hours of administration or decades later Survivors are five to six times more likely than sibling controls to develop cardiovascular disease of various etiologies, including symptomatic heart failure, asymptomatic ventricular dysfunction, valvar disease, coronary disease, arrhythmias, autonomic dysfunction, vascular changes, and pericardial disease The field of cardio-oncology is focused on prevention, surveillance, and treatment of CTC Keywords Cardio-oncology; cardiomyopathy; heart failure; oncology; cancer; anthracycline; chemotherapy; radiation therapy