FIGURE 69.14 Infant with acute hemorrhagic edema of infancy Hemangiomas Hemangiomas of infancy (infantile hemangiomas) represent benign vascular tumors that are present in approximately 3% of newborns and up to 10% of all infants These are seen more frequently in premature and low–birth-weight infants and occur more commonly in girls than in boys Superficial lesions possess a red color, resembling a strawberry or raspberry Deep lesions appear soft, compressible, and often are faintly bluish Mixed lesions may show features of both superficial and deep hemangiomas A precursor lesion may or may not be noticeable immediately at birth They typically undergo an early rapid growth phase between and weeks old, continue to proliferative phase during the first to months, plateau in growth during the second months, and then begin a slow process of involution that lasts a few years Beta-blockers, specifically systemic propranolol and topical timolol, are used to treat severe hemangiomas of infancy Potential complications include bradycardia, hypotension, hypoglycemia,