FIGURE 70.15 Kaposi varicelliform eruption Note the crusted vesicles and pustules concentrated in areas where the pre-existing eczema has been active Kaposi Varicelliform Eruption KVE is a collective term that indicates an acute, often rapidly progressive, viral secondary infection of an underlying inflammatory skin condition ( Table 70.2 ) When herpes simplex virus, enterovirus, or vaccinia virus secondarily infects the skin in atopic dermatitis, the condition is referred to as eczema herpeticum (EH), eczema enteroviricum (coxsackium), or eczema vaccinatum, respectively Less commonly, inflammatory diseases such as psoriasis, PRP, or blistering skin diseases like pemphigus vulgaris, pemphigus foliaceus, keratosis follicularis (Darier disease), or benign familial pemphigus (Hailey–Hailey disease) can become infected, usually with herpes simplex virus and less commonly, varicella zoster virus Similarly, contact dermatitis, sunburn, or other more acute skin barrier damage can provide a temporary opportunity for the same phenomenon to occur outside of a chronic skin condition The hallmarks of the condition are the acute onset and rapid progression of viral skin lesions Initially localized vesicles or pustules will rapidly