pustules, in addition to laboratory evaluation, will help distinguish AGEP from DHR Eliciting either a personal or family history of psoriasis or a history of a high-risk medication can help favor a diagnosis of either pustular psoriasis or AGEP, respectively AGEP generally resolves with desquamation within to 10 days after stopping the drug Topical steroids and oral antihistamines can provide symptomatic relief if needed FIGURE 68.5 Erythema caloricum: back (Courtesy of Benjamin Barankin, MD, Edmonton, Alberta, Canada In: Stedman’s Medical Dictionary for the Health Professions and Nursing 7th ed Wolters Kluwer: Philadelphia, PA; 2012.) VESICULOBULLOUS Fixed Drug Fixed drug eruption generally appears as a sharply demarcated erythematous to dusky, edematous oval, or circular plaque ( Fig 68.6 ) The plaques may become bullous Lesions can appear anywhere, but the lips, face, hands, feet, and genitals are commonly affected They often leave hyperpigmentation that may take