TABLE 57.1 CAUSES OF DYSURIA: SYSTEMIC CONDITIONS Disorder Signs and symptoms Stevens–Johnson syndrome (see Chapter 88 Dermatologic Urgencies and Emergencies ) Reactive arthritis (Reiter syndrome) Crohn disease (see Chapter 91 Gastrointestinal Emergencies ) Beh ỗet syndrome Mucous membrane changes, Genital ulcerations; target conjunctivitis, oral lesions ulcerations, urethritis Conjunctivitis, arthritis, urethritis; more common in males Dysuria (often in setting of UTI); fistula formation (complication) Physical examination No GU findings; joint pain (including heels, digits, and spine) Perianal inflammation or perianal skin tags; may have associated fistulas or abscess Recurrent oral ulcerations, Genital ulcerations ocular panuveitis, vasculitis, genital ulcerations (less common) Malignancy/tumor Constitutional symptoms: No GU findings; abdominal fatigue, weight loss, and mass most common (see Chapter 98 fever; genitourinary Oncologic symptoms related to intraEmergencies ) abdominal mass