TABLE 89.8 SOME CAUSES OF SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION IN CHILDREN Disorders of central nervous system Infection (meningitis, encephalitis) Trauma, post-neurosurgery Hypoxic insults, especially in the perinatal period Brain tumor Intraventricular hemorrhage Guillain–Barré syndrome Psychosis Intrathoracic disorders Infection (tuberculosis, pneumonia, empyema) Positive pressure ventilation Asthma Cystic fibrosis Pneumothorax Patent ductus arteriosus ligation Miscellaneous Pain (e.g., after abdominal surgery) Nausea Severe hypothyroidism Tumors (e.g., neuroblastoma) Drug induced Increased antidiuretic hormone secretion Vincristine Cyclophosphamide Carbamazepine Adenine arabinoside Phenothiazines Morphine Potentiation of antidiuretic hormone effect Acetaminophen Indomethacin Clinical Considerations Clinical Recognition