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Infectious Disease Emergencies Systemic Infections (Bacteremia and Shock, Rickettsial Diseases, Babesiosis) Andreola B, Bressan S, Callegaro S, et al Procalcitonin and C-reactive protein as diagnostic markers of severe bacterial infections in febrile infants and children in the emergency department Pediatr Infect Dis J 2007;26(8):672– 677 Benito-Fernandez J, Mintegi S, Pocheville-Gurutezeta I, et al Pneumococcal bacteremia in febrile infants presenting to the emergency department years after the introduction of the pneumococcal conjugate vaccine in the Basque Country of Spain Pediatr Infect Dis J 2010;29(12):1142–1144 Biondi E, Evans R, Mischler M, et al Epidemiology of bacteremia in febrile infants in the United States Pediatrics 2013;132(6):990–996 Brauner M, Goldman M, Kozer E Extreme leukocytosis and the risk of serious bacterial infection in febrile children Arch Dis Child 2010;95(3):209–212 Bressan S, Andreola B, Cattelan F, et al Predicting severe bacterial infections in well-appearing febrile neonates: laboratory markers’ accuracy and duration of fever Pediatr Infect Dis J 2010;29(3):227–232 Carstairs KL, Tanen DA, Johnson AS, et al Pneumococcal bacteremia in febrile infants presenting to the emergency department before and after the introduction of the heptavalent pneumococcal vaccine Ann Emerg Med 2007;49(6):772–777 Cruz AT, Mahajan P, Bonsu BK, et al Accuracy of complete blood cell counts to identify febrile infants 60 days or younger with invasive bacterial infections JAMA Pediatr 2017;171(11):e172927 De S, Williams GJ, Hayen A, et al Value of white cell count in predicting serious bacterial infection in febrile children under years of age Arch Dis Child 2014;99(6):493–499 Gomez B, Mintegi S, Bressan S, et al Validation of the “Step-by-Step” approach in the management of young febrile infants Pediatrics 2016;138(2):e20154381 Graham J, Stockley K, Goldman RD Tick-borne illnesses: a CME update Pediatr Emerg Care 2011;27(2):141–147; quiz 148–150 Greenhow TL, Hung YY, Herz A Bacteremia in children to 36 months after introduction of conjugated pneumococcal vaccines Pediatrics 2017;139(4):e20162098 Jaffe DM, Fleisher GR Temperature and total white blood count as indicators of bacteremia Pediatrics 1991;87(5):670–674 Kuppermann N, Dayan PS, Levine DA, et al A clinical prediction rule to identify febrile infants 60 days and younger at low risk for serious bacterial infections JAMA Pediatr 2019;173(4):342–351 Kuppermann N, Walton EA Immature neutrophils in the blood smears of young febrile children Arch Pediatr Adolesc Med 1999;153(3):261–266 Laupland KB, Gregson DB, Vanderkooi OG, et al The changing burden of pediatric bloodstream infections in Calgary, Canada, 2000–2006 Pediatr Infect Dis J 2009;28(2):114–117 Lee GM, Fleisher GR, Harper MB Management of febrile children in the age of the conjugate pneumococcal vaccine: a cost-effectiveness analysis Pediatrics 2001;108(4):835–844 Mahajan P, Grzybowski M, Chen X, et al Procalcitonin as a marker of serious bacterial infections in febrile children younger than years old Acad Emerg Med 2014;21(2):171–179 Mistry RD, Wedin T, Balamuth F, et al Emergency department epidemiology of pneumococcal bacteremia in children since the institution of widespread PCV7 vaccination J Emerg Med 2013;45(6):813–820 Powell EC, Mahajan PV, Roosevelt G, et al Epidemiology of bacteremia in febrile infants 60 days and younger Ann Emerg Med 2018;71(2):211–216 Pulliam PN, Attia MW, Cronan KM C-reactive protein in febrile children to 36 months of age with clinically undetectable serious bacterial infection Pediatrics 2001;108(6):1275–1279 Rudinsky SL, Carstairs KL, Reardon JM, et al Serious bacterial infections in febrile infants in the post-pneumococcal conjugate vaccine era Acad Emerg Med 2009;16(7):585–590 Sard B, Bailey MC, Vinci R An analysis of pediatric blood cultures in the postpneumococcal conjugate vaccine era in a community hospital emergency department Pediatr Emerg Care 2006;22(5):295–300 Shah SS, Shofer FS, Seidel JS, et al Significance of extreme leukocytosis in the evaluation of febrile children Pediatr Infect Dis J 2005;24(7):627–630 Simonsen KA, Harwell JI, Lainwala S Clinical presentation and treatment of transfusion-associated babesiosis in premature infants Pediatrics 2011;128(4):e1019–e1024 Stanley R, Pagon Z, Bachur R Hyperpyrexia in infants younger than months Pediatr Emerg Care 2005;21(5):291–294 Stoll ML, Rubin LG Incidence of occult bacteremia among highly febrile young children in the era of the pneumococcal conjugate vaccine: a study from a Children’s Hospital Emergency Department and Urgent Care Center Arch Pediatr Adolesc Med 2004;158(7):671–675 Trautner BW, Caviness AC, Gerlacher GR, et al Prospective evaluation of the risk of serious bacterial infection in children who present to the emergency department with hyperpyrexia (temperature of 106 degrees F or higher) Pediatrics 2006;118(1):34–40 Wilkinson M, Bulloch B, Smith M Prevalence of occult bacteremia in children aged to 36 months presenting to the emergency department with fever in the post pneumococcal conjugate vaccine era Acad Emerg Med 2009;16(3):220– 225 Woll C, Neuman MI, Pruitt CM, et al Epidemiology and etiology of invasive bacterial infection in infants < = 60 days old treated in emergency departments J Pediatr 2018;200:210–217 Woods CR Rocky Mountain spotted fever in children Pediatr Clin North Am 2013;60:455–470 Yo CH, Hsieh PS, Lee SH, et al Comparison of the test characteristics of procalcitonin to C-reactive protein and leukocytosis for the detection of serious bacterial infections in children presenting with fever without source: a systematic review and meta-analysis Ann Emerg Med 2012;60(5):591–600 Central Nervous System Infections (Meningitis, Encephalitis, Brain Abscesses, Botulism, Tetanus) Centers for Disease Control and Prevention Acute flaccid myelitis (AFM): 2018 case definition Available online at https://wwwn.cdc.gov/nndss/conditions/acute-flaccid-myelitis/casedefinition/2018/ Cohn KA, Thompson AD, Shah SS, et al Validation of a clinical prediction rule to distinguish Lyme meningitis from aseptic meningitis Pediatrics 2012;129(1):e46–e53 Cruz AT, Freedman SB, Kulik DM, et al Herpes simplex virus infection in infants undergoing meningitis evaluation Pediatrics 2018;141(2):e20171688 Garro AC, Rutman M, Simonsen K, et al Prospective validation of a clinical prediction model for Lyme meningitis in children Pediatrics 2009;123(5):e829–e834 Goodkin HP, Harper MB, Pomeroy SL Intracerebral abscesses in children: historical trends at Children’s Hospital Boston Pediatrics 2004;113(6):1765– 1770 Halgrimson WR, Chan KH, Abzug MJ, et al Incidence of acute mastoiditis in Colorado children in the pneumococcal conjugate vaccine era Pediatr Infect Dis J 2014;33(5):453–457 Hardasmalani MD, Saber M Yield of diagnostic studies in children presenting with complex febrile seizures Pediatr Emerg Care 2012;28(8):789–791 Hill HA, Elam-Evans LD, Yankey D, et al Vaccination coverage among children aged 19–35 months—United States, 2017 MMWR Morb Mortal Wkly Rep 2018;67(40):1123–1128 Kaplan SL, Barson WJ, Lin PL, et al Early trends for invasive pneumococcal infections in children after the introduction of the 13-valent pneumococcal conjugate vaccine Pediatr Infect Dis J 2013;32(3):203–207 Nigrovic LE, Kuppermann N, Malley R, et al Children with bacterial meningitis presenting to the emergency department during the pneumococcal conjugate vaccine era Acad Emerg Med 2008;15(6):522–528 Pifko E, Price A, Sterner S Infant botulism and indications for administration of botulism immune globulin Pediatr Emerg Care 2014;30(2):120–124; quiz 125–127 Pinninti SG, Kimberlin DW Neonatal herpes simplex virus infections Pediatr Clin North Am 2013;60(2):351–365 Sejvar JJ, Lopez AS, Cortese MM, et al Acute flaccid myelitis in the United States, August-December of 2014: results of nationwide surveillance Clin Infect Dis 2016;63(6):737–745 Seltz LB, Smith J, Durairaj VD, et al Microbiology and antibiotic management of orbital cellulitis Pediatrics 2011;127(3):e566–e572 Subcommittee on Febrile Seizures of the American Academy of Pediatrics Neurodiagnostic evaluation of the child with a simple febrile seizure Pediatrics 2011;127(2):389–394 Tunkel AR, Glaser CA, Bloch KC, et al The management of encephalitis: clinical practice guidelines by the Infectious Diseases Society of America Clin Infect Dis 2008;47(3):303–327 Tunkel AR, Hartman BJ, Kaplan SL, et al Practice guidelines for the management of bacterial meningitis Clin Infect Dis 2004;39(9):1267–1284 Upper and Lower Respiratory Tract Infections Bradley JS, Byington CL, Shah SS, et al The management of communityacquired pneumonia in infants and children older than months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and ... cellulitis Pediatrics 2011;127(3):e566–e572 Subcommittee on Febrile Seizures of the American Academy of Pediatrics Neurodiagnostic evaluation of the child with a simple febrile seizure Pediatrics... serious bacterial infection in children who present to the emergency department with hyperpyrexia (temperature of 106 degrees F or higher) Pediatrics 2006;118(1):34–40 Wilkinson M, Bulloch B, Smith... from aseptic meningitis Pediatrics 2012;129(1):e46–e53 Cruz AT, Freedman SB, Kulik DM, et al Herpes simplex virus infection in infants undergoing meningitis evaluation Pediatrics 2018;141(2):e20171688

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