TABLE 101.1 CRITERIA FOR CLASSIFICATION OF SYSTEMIC LUPUS ERYTHEMATOUS ACR criteria-1997 SLICC criteria2012 Criterion Definition Criterion Definition Malar rash Fixed erythema, flat or Acute cutaneous raised, over the lupus malar eminences, tending to spare the nasolabial folds Discoid rash Erythematous raised Chronic cutaneous Classic discoid rash patches with lupus localized (above adherent keratotic the neck); scaling and follicular generalized plugging; atrophic (above and below scaring may occur in the neck); older lesions hypertrophic (verrucous) lupus; lupus panniculitis (profundus); Lupus malar rash (do not count if malar discoid); bullous lupus; toxic epidermal necrolysis variant of SLE; maculopapular lupus rash; photosensitive lupus rash (in the absence of dermatomyositis); or subacute cutaneous lupus (nonindurated psoriasiform and/or annular polycyclic lesions that resolve without scarring, although occasionally with postinflammatory dyspigmentation or telangiectasias) mucosal lupus; lupus erythematosus tumidus; chilblains lupus; or discoid lupus/lichen planus overlap Photosensitivity Skin rash as a result of unusual reaction to sunlight, by patient history or physician observation Oral ulcers Oral or nasopharyngeal Oral/nasal ulcers ulceration, usually painless, observed by a physician Nonscarring alopecia Arthritis Palate, buccal, tongue, or nasal ulcers (in the absence of other causes, such as vasculitis, Behỗets, infection [herpes], inflammatory bowel disease, reactive arthritis, and acidic foods) Diffuse thinning or hair fragility with visible broken hairs (in the absence of other causes such as alopecia areata, drugs, iron deficiency and androgenic alopecia) Nonerosive arthritis Synovitis involving Characterized by involving two or two or more swelling or more peripheral joints effusion or joints, characterized tenderness in two by tenderness, swelling, or effusion Pleuritis or pericarditis Pleuritis—convincing Serositis history or pleuritic pain or rub heard by a physician or evidence of pleural effusion or Pericarditis— documented by EKG, rub, or evidence of pericardial effusion on echocardiography Renal disorder Persistent proteinuria Renal disorder >0.5 g/day or >3% if quantitation not performed or cellular casts—may be red cell, hemoglobin, granular, tubular, or mixed Neurologic Seizures or psychosis Neurologic disorder —in the absence of disorder offending drugs or known metabolic derangements (uremia, or more joints and 30 minutes or more of morning stiffness Typical pleurisy for more than day or pleural effusions or pleural rub, or typical pericardial pain (pain with recumbency improved by sitting forward) for more than day, or pericardial effusion, or pericardial rub or pericarditis by EKG in the absence of other causes, such as infection, uremia, and Dressler’s pericarditis Urine protein-tocreatine ratio (or 24-hr urine protein) representing 500 mg protein/24 hrs or red blood cell casts Seizures; psychosis; mononeuritis multiplex (in the absence of other known causes such as primary