Textbook of Men’s Health and Aging 2nd Edition ppt

[...]... Section VIII: Cardiovascular and Respiratory System 35 Atherosclerotic risk assessment of androgen therapy in aging men David Crook 36 Male aging: changes in metabolic, inflammatory, and endothelial indices of cardiovascular risk Ian F Godsland 37 Androgens: Studies in animal models of atherosclerosis Peter Alexandersen 38 Androgens and blood pressure in men Guy Lloyd 39 Androgens and arterial disease Carolyn... of hearing.1 The history of research on elderly mens health reflects most parts of the broad cultural history and, therefore, an attempt to press this field into only one chapter of a textbook is at the beginning an act of despair Additionally, the story of the fountain of youth for males is also the story of wrong ways, blind alleys, hasty speculations, and of charlatanism Christian Wilhelm Hufeland... 72 with several subcutaneous injections of a mixture of blood from the testicular veins, semen, and juice extracted from crushed testicles of young and vigorous dogs and guinea pigs in 1889 was one of the first milestones for androgen therapy in the aging male He reported an increase in his physical and mental abilities, a better stream of urine and the relief of constipation Brown-Sộquard had inspired... organisms is an increase in the incidence of disease and the risk of death This definition then makes the distinction between the aging process and disease It assumes that there are fundamental aging processes that are not just the sum of all of the diseases of aging These processes predispose the aging organism to a greater likelihood of disease Why do we age? The question of why we age can be approached from... Section VI: Aging and Body Composition 21 Aging testosterone, and body composition Alex Vermeulen 22 Growth hormone & body composition in the aging male Fred Sattler 23 Androgens & lean body mass in the aging male Melinda Sheffield-Moore, Shanon Casperson & Randall J Urban 24 Visceral obesity, androgens and the risks of cardiovascular disease Louis JG Gooren 281 283 Section VII: Nutrition, Digestion and Metabolism... date of birth of the science of internal secretion is that memorable meeting of the Sociộtộ de Biologie of Paris of June 1st 1889, where BrownSộquard, then 72 years of age reported on his experiments undertaken to prove his hypothesis by means of subcutaneous injections of testicular juice into himself. In 1902, Ancel and Bouin in France ligated the ductus deferens in rabbits and noted atrophy of the... extracts from up to 100 g of testes were required for a positive result in the so-called chick comb bioassay.2,48 It is not surprising, therefore, that 15 mg of the first known androgen androsterone was isolated under the leadership of Adolf Butenandt, at the age of 28 5 Lunenfeld Introduction.qxd 8/23/2007 4:48 PM Page 6 Textbook of health in aging men years, 15 00025 000 liters of policemens urine in... 1931.49,50 The name of this relatively weak urinary 5-reduced androgen comes from andro = male, ster = sterol, and one = ketone The chemical synthesis of androsterone was performed by Leopold Ruzicka and co-workers 3 years later.51 The Japanese workers Ogata and Hirano,52 not sufficiently acknowledged by the Europeans and Americans, found in 1934 that the androgen from the urine (Butenandts androsterone)... sterol, and one = ketone In the same year, the chemical synthesis of testosterone was published by three groups from Germany, the Netherlands, and Switzerland, led by Adolf Butenandt,54 Ernst Laqueur,53 and Leopold Ruzicka.55 Ruzicka and Butenandt were offered the 1939 Nobel Prize for chemistry for their work, but Butenandt was forced by the Nazi government to decline the honor Adolf Butenandt wrote... transplanted testes affect behavioral and sexual 1 Lunenfeld Introduction.qxd 8/23/2007 4:48 PM Page 2 Textbook of health in aging men characteristics by secreting a substance into the blood stream Aging as an endocrine disorder? The earliest contribution of modern medicine to the understanding of the clinical features of a disorder related to the beginning of aging was the article On the climacteric . alt="" Textbook of Men’s Health and Aging 2 nd Edition Lunenfeld Prelims.qxd 8/23/2007 5:46 PM Page i Lunenfeld Prelims.qxd 8/23/2007 5:46 PM Page ii Textbook. 8/23/2007 5:46 PM Page ii Textbook of Men’s Health and Aging 2 nd Edition Editors in Chief Bruno Lunenfeld MD FRCOG FACOG [Hon] Professor Emeritus, Reproductive