Overall, mortality following pediatric shock has declined dramatically over the past several decades with improved recognition and implementation of goaldirected resuscitation protocols Recent estimates suggest mortality rates between 3% and 6% for pediatric patients presenting to an ED with shock from all etiologies The World Health Organization reports that hypovolemic shock due to diarrhea accounts for 760,000 deaths in children less than years each year In the United States, estimates of in-hospital mortality following pediatric septic shock range from 4.2% to ∼20% depending on the patient population and how the diagnosis of sepsis is determined (e.g., billing codes vs chart review) Infants