Alter MJ Prevention of spread of hepatitis C Hepatology 2002;36(5 suppl 1):S93–S98 Mack CL, Gonzalez-Peralta RP, Gupta N, et al; North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition NASPGHAN practice guidelines: diagnosis and management of hepatitis C infection in infants, children, and adolescents J Pediatr Gastroenterol Nutr 2012;54(6):838–855 Murray KF, Balistreri WF, Bansal S, et al Safety and Efficacy of LedipasvirSofosbuvir With or Without Ribavirin for Chronic Hepatitis C in Children Ages 6–11 Hepatology 2018;68:2158–2166 NIH consensus statement on management of hepatitis C: 2002 NIH Consens State Sci Statements 2002;19(3):1–46 Pratt DS, Kaplan MM Evaluation of abnormal liver-enzyme results in asymptomatic patients N Engl J Med 2000;342(17):1266–1271 Sokal EM, Bortolotti F Update on prevention and treatment of viral hepatitis in children Curr Opin Pediatr 1999;11(5):384–389 Terrault NA, Lok ASF, McMahon BJ, et al Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance Hepatology 2018;67:1560–1599 Gastroesophageal Reflux Disease Lightdale JR, Gremse DA Gastroesophageal reflux: management guidance for the pediatrician Pediatrics 2013;131(5):e1684–e1695 Mousa H, Hassan M Gastroesophageal Reflux Disease Pediatr Clin N Am 2017;64(3):487–505 Vandenplas Y, Rudolph CD, Di Lorenza C, et al Pediatric gastroesophageal reflux clinical practice guidelines: joint recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) J Pediatr Gastroenterol Nutr 2009;49(4):498–547 Celiac Disease Garnier-Lengliné H, Cerf-Bensussan N, Ruemmele FM Celiac disease in children Clin Res Hepatol Gastroenterol 2015;39(5):544–551 Green PH, Cellier C Celiac disease N Engl J Med 2007;357(17):1731–1743 Hill ID, Dirks MH, Liptak GS, et al; North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition J Pediatr Gastroenterol Nutr 2005;40(1):1–19 Mesenteric Lymphadenitis Helbling R, Conficconi E, Wyttenback M, et al Acute nonspecific mesenteric lymphadenitis: more than “no need for surgery” Biomed Res Int 2017:9784565 Simanovsky N, Hiller N Importance of sonographic detection of enlarged abdominal lymph nodes in children J Ultrasound Med 2007;26(5):581– 584 Vayner N, Coret A, Polliack G, et al Mesenteric lymphadenopathy in children examined by US for chronic and/or recurrent abdominal pain Pediatr Radiol 2003;33:864–867 Reye Syndrome Bhutta AT, Van Savell H, Schexnayder SM Reye’s syndrome: down but not out South Med J 2003;96(1):43–45 da Silveira EB, Young K, Rodriguez M, et al Reye’s syndrome in a 17 yearold male: is this disease really disappearing? Dig Dis Sci 2002;47(9):1959– 1961 Glasgow JF, Middleton B Reye syndrome—insights on causation and prognosis Arch Dis Child 2001;85(5):351–353 McGovern MC, Glasgow JF, Stewart MC Lesson of the week: Reye’s syndrome and aspirin: lest we forget BMJ 2001;322(7302):1591–1592 Schrör K Aspirin and Reye syndrome: a review of the evidence Pediatr Drugs 2007;9(3):195–204 CHAPTER 92 ■ GYNECOLOGY EMERGENCIES PAYAL K GALA, ALETHA Y AKERS, MEG WOLFF GOALS OF EMERGENCY CARE Pediatric gynecologic complaints are common and are often accompanied by considerable anxiety The goals of evaluation in the emergency department (ED) are to identify life-threatening etiologies, such as ruptured ectopic pregnancy, to ensure appropriate diagnosis and treatment of nonemergency etiologies, such as infection and disorders of menstruation, and to ensure appropriate follow-up care with subspecialists or the primary care physician KEY POINTS Pregnancy should be considered in all adolescent patients presenting to the emergency department Patients with severe abnormal uterine bleeding should be quickly assessed for hemodynamic instability Pelvic inflammatory disease can lead to long-term pain and dysfunction if the diagnosis is missed or the condition is inadequately treated RELATED CHAPTERS Signs and Symptoms Breast Lesions: Chapter 16 Inguinal Masses: Chapter 39 Oligomenorrhea: Chapter 51 Vaginal Bleeding: Chapter 79 Vaginal Discharge: Chapter 80 Medical, Surgical, and Trauma Emergencies Infectious Disease Emergencies: Chapter 94 Genitourinary Trauma: Chapter 108 Genitourinary Emergencies: Chapter 119 Behavioral and Psychiatric Emergencies: Chapter 126 Sexual Assault: Child and Adolescent: Chapter 127 The Children’s Hospital of Philadelphia Clinical Pathways ED Pathway for Evaluation of Postpubertal Girls With Lower Abdominal Pain and No Vaginal Bleeding URL: https://www.chop.edu/clinical-pathway/abdominal-pain-lowerpost-pubertal-girls-clinical-pathway Authors: C Mollen, MD; J Lavelle, MD; M Zucker, MD Posted: April 2006, revised September 2011, April 2015, October 2017, December 2017 Evaluation/Treatment of Acute Abnormal Uterine Bleeding URL: https://www.chop.edu/clinical-pathway/uterine-bleeding-acuteabnormal-clinical-pathway Authors: M Zucker, MD; R Hughes, Pharm D; A Culyba, MD; L Zinns, MD; J Boyle, RN; C Jacobstein, MD; J Posner, MD; J Lavelle, MD Posted: June 2015, revised July 2017 PREGNANCY Goals of Treatment ... AKERS, MEG WOLFF GOALS OF EMERGENCY CARE Pediatric gynecologic complaints are common and are often accompanied by considerable anxiety The goals of evaluation in the emergency department (ED)... Society for Pediatric Gastroenterology, Hepatology and Nutrition Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric. .. etiologies, such as ruptured ectopic pregnancy, to ensure appropriate diagnosis and treatment of nonemergency etiologies, such as infection and disorders of menstruation, and to ensure appropriate