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References Pasquali SK, Jacobs JP, Farber GK, et al Report of the national heart, Lung, and blood institute working group: an integrated network for congenital heart disease research Circulation 2016;133:1410–1418 Pasquali SK, Schumacher KR, Davies RR Can linking databases answer questions about pediatric heart failure? Cardiol Young 2015;25(suppl 2):160–166 Pasquali SK, Jacobs ML, Jacobs JP Linking Databases Pediatric and Congenital Cardiac Care: Outcomes Analysis, Quality Improvement, and Patient Safety Springer-Verlag: London, UK.; 2015 Pasquali SK, Li JS, Jacobs ML, Shah SS, Jacobs JP Opportunities and challenges in linking information across databases in pediatric cardiovascular medicine Prog Pediatr Cardiol 2012 Why “big data” is a big deal [Available at] http://harvardmagazine.com/2014/03/why-bigdata-is-a-big-deal Merelli I, Perez-Sanchez H, Gesing S, D'Agostino D Managing, analyzing, and integrating big data in medical bioinformatics: open problems and future perspectives Biomed Res Int 2014;2014:134023 Using big data to fight range anxiety in electric vehicles http://spectrum.ieee.org/cars-thatthink/transportation/sensors/using-big-data-tofight-range-anxiety-in-electric-vehicles Big data case study – Hospitality – Red Roof Inn http://retailxp.com/hospitality-big-datacase-study-red-roof-inn/ Califf RM, Peterson ED, Gibbons RJ, et al Integrating quality into the cycle of therapeutic development J Am Coll Cardiol 2002;40:1895– 1901 10 Sullivan BA, Fairchild KD Predictive monitoring for sepsis and necrotizing enterocolitis to prevent shock Semin Fetal Neonatal Med 2015 11 Alberts B, Kirschner MW, Tilghman S, Varmus H Rescuing US biomedical research from its systemic flaws Proc Natl Acad Sci USA 2014;111:5773–5777 12 Lauer MS, D'Agostino RB The randomized registry trial-the next disruptive technology in clinical research? N Engl J Med 2013;369:1579–1581 13 Porter ME What is value in health care? N Engl J Med 2010;363:2477–2481 14 Big Data to Knowledge Initiative http://bd2k.nih.gov/about_bd2k.html#sthash.GsGUsKgu.c 15 Collins FS, Varmus H A new initiative on precision medicine N Engl J Med 2015;372:793–795 16 Pasquali SK, Jacobs ML, Jacobs JP Linking databases Barach P, Jacobs JP, Lipshultz SE, Laussen P Pediatric and Congenital Cardiac Disease: Outcomes Analysis, Quality Improvement, and Patient Safety SpringerVerlag: London, UK; 2015 17 Vener DF, Gaies MG, Jacobs JP, Pasquali SK Clinical databases and registries in congenital cardiac surgery, critical care, and anesthesiology worldwide World J Pediatr Congenit Heart Surg 2017;8:77–87 18 Riehle-Colarusso TJ, Bergersen L, Broberg CS, Oster ME for the Congenital Heart Public Health Consortium, et al Databases for congenital heart defect public health studies across the lifespan J Am Heart Assoc 2016;5:e004148 19 Pasquali SK, Ravishankar C, Romano JC, et al Design and initial results of a programme for routine standardised longitudinal follow-up after congenital heart surgery Cardiol Young 2016;26:1590–1596 ... Pasquali SK, Jacobs ML, Jacobs JP Linking databases Barach P, Jacobs JP, Lipshultz SE, Laussen P Pediatric and Congenital Cardiac Disease: Outcomes Analysis, Quality Improvement, and Patient Safety

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