Pediatric emergency medicine trisk 648

Treatment in the ED should be directed at cardiorespiratory stabilization of the infants, fluid resuscitation of neonates in septic shock, followed by assessment for bacterial and viral causes of sepsis Neonates with suspected HSV should be admitted to the hospital and started on intravenous acyclovir therapy (60 mg/kg/day in three divided doses) Infants with keratitis or ocular disease should also be given topical antiviral ophthalmic drops (1% trifluridine, 0.1% iododeoxyuridine, or 3% vidarabine), in addition to intravenous acyclovir therapy Neonates should be placed on contact precautions Infants receiving therapy have a mortality rate of 29% in disseminated disease, 4% in CNS disease, and