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[...]... history ofschizophrenia (and, therefore, a greater likelihood of carrying a gene for the illness) (Marcelis et al., 1998) Whatever the cause, the result ofthe obstetric complications is to further increase the risk ofschizophrenia in the offspring of women with schizophrenia On a positive note, there is good evidence that improved obstetric care can lead to a lower incidence ofschizophreniaThe large... person with schizophrenia) the risk is close to 50 per cent (Gottesman, 1991) Studies of people adopted in infancy reveal that the increased risk ofschizophrenia among the relatives of people with the illness is due to inheritance rather than environmentThe children of people with schizophrenia have the same increased prevalence ofthe illness whether they are raised by their biological parent with... magnetic resonance Introduction 11 imaging (MRI) reveal changes in the size of different parts ofthe brain, especially in the temporal lobes The fluid-filled spaces (the ventricles) in the interior ofthe temporal lobes are often enlarged and the temporal lobe tissue diminished The greater the observed changes the greater the severity ofthe person’s thought disorder and his or her auditory hallucinations... that the outcome is often favorable It is also true to say that schizophrenia usually becomes less severe as the person with the illness grows older In addition, the later the illness begins in life, the milder it proves to be Women usually develop their first symptoms ofschizophrenia later than men and the course of their illness tends to be less severe Onset ofschizophrenia before the age of 14... States the diagnostic approach to schizophrenia used to be very broad With the publication, in 1980, ofthe third edition of the American Psychiatric Association’s Diagnostic and Statistical Manual, however, American psychiatry switched from one ofthe broadest concepts ofschizophrenia in the world to one ofthe narrowest Why is the diagnosis so susceptible to fashion? The underlying problem is that schizophrenia. .. developing world, the point prevalence ofschizophrenia (the number of cases to be found at any time) is lower in the developing world—around 3 per 1,000 of the population compared to 6 per 1,000 in the developed world (Warner and de Girolamo, 1995) The risk of developing the illness at some time in one’s life (the lifetime prevalence) is a little higher—around 1 per cent of the population in the developed... enjoying broad public recognition, such theories have seldom been adequately tested, and none of the research satisfactorily resolves the question of whether differences found in the families of people with schizophrenia are the cause or the effect of psychological abnormalities in the disturbed family member (Hirsch and Leff, 1975) Millions of relatives of people with schizophrenia have suffered needless... majority of recent epidemiological studies looking at changes in the incidence ofschizophrenia in countries around the world indicate a substantial decrease in the occurrence ofthe illness since the Second World War Several studies from Britain, Scandinavia and New Zealand reveal a decrease in the incidence of schizophrenia ofthe order of 40 to 60 per cent over 10- to 15-year time-spans during the period... course of illness Onset after the age of 40 is also rare, and is associated with a milder course What causes schizophrenia? There is no single organic defect or infectious agent which causes schizophrenia, but a variety of factors increase the risk of getting the illness—among them, genetics and obstetric complications Genetics Relatives of people with schizophrenia have a greater risk of developing the. .. Sacker et al., 1996) They are, therefore, a much more prominent cause ofschizophrenia than maternal viral infection, which probably explains no more than 2 per cent of cases ofthe illness (Sham et al., 1992) The authors ofthe meta-analysis estimate that complications of pregnancy and delivery increase the prevalence ofschizophrenia by 20 per cent (Geddes and Lawrie, 1995) The obstetric complications .
The Environment of
Schizophrenia
There is now a body of evidence suggesting that the occurrence and
course of schizophrenia are affected by a variety of. is schizophrenia?
In the title of this book, The Environment of Schizophrenia, the term
environment is intended to encompass everything that affects the