SR and MA CCACE Workshop Programme resources 271117_Susie Shenkin

Workshop on Systematic Reviews and Meta-Analyses in Cognitive Ageing and Cognitive Epidemiology Research Monday 27th November, 2017 Room 7.01, Dugald Stewart Building, School of PPLS, University of Edinburgh 09.00 – 09.30 Introduction to systematic reviews Susan Shenkin Geriatric Medicine, University of Edinburgh Medical School 09.30 – 10.30 Introduction to Literature Searching for Systematic Reviews Anne Donnelly Academic Support Librarian (Philosophy, Psychology & Language Sciences), University of Edinburgh 10.30 – 10.45 Coffee / Tea 10.45 – 11.15 Data extraction, quality assessment, and writing up Rebecca Woodfield Geriatric Medicine, NHS Lothian 11.15 – 11.30 Practical hints and tips Ellen Backhouse/Caroline McHutchison Centre for Clinical Brain Sciences, University of Edinburgh 11.30 – 12.30 Introduction to meta-analysis Mike Allerhand CCACE, University of Edinburgh 12.30 – 13.30 Lunch Greenfield Computer Lab, George Square 13.30 – 14.00 Introduction to meta-analysis (continued) Mike Allerhand CCACE, University of Edinburgh 14.00 - 16.00 Workshop on literature searching for systematic reviews Anne Donnelly 16.00 – 16.10 Round-up and questions Resources Systematic Review Guidelines and Methodology Centre for Cognitive Ageing and Cognitive Epidemiology (CCACE: slides and resources from this course http://www.ccace.ed.ac.uk/research/software-resources/systematic-reviewsand-meta-analyses Or http://tinyurl.com/sysrev1 Cochrane UK has a wealth of useful information, with focus on intervention studies for healthcare: http://uk.cochrane.org/author-resources The Centre for Reviews and Dissemination provides useful information for the review of medical studies Systematic Reviews: CRD’s guidance for undertaking reviews in health care http://www.york.ac.uk/inst/crd/index_guidance.htm The Campbell Collaboration website lists useful links to methodology sites, with focus on evidence based policy and practice: http://www.campbellcollaboration.org/resources/research/Methods_Links.php The Evidence for Policy and Practice Information and Co-ordinating Centre (EPPI-Centre) provides an online evidence library, and methods and tools for completing systematic reviews relevant to public policy: http://eppi.ioe.ac.uk/cms/ The EQUATOR Network website seeks to improve reliability and value of medical research literature by promoting transparent and accurate reporting of research studies: http://www.equator-network.org/ The International prospective register of systematic reviews (PROSPERO) website, administered by the Centre for Reviews and Dissemination (CRD) at the University of York, provides information on registering systematic reviews in healthcare, and provides links to useful webpages on methodology and reporting: http://www.crd.york.ac.uk/PROSPERO/ The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) provides a minimum set of evidence-based items that all authors should comply with in reporting their systematic review and/or meta-analysis: http://www.prisma-statement.org/ The Scottish Intercollegiate Guidelines Network (SIGN) provides information on how to conduct a systematic literature review, and helpfully has assessment checklists for cohort and case-control studies: http://www.sign.ac.uk/guidelines/fulltext/50/section6.html Online Second Edition of Systematic Reviews in Health Care: Meta-Analysis in Context (Egger, Davey Smith, & Altman, 2008): http://www.blackwellpublishing.com/medicine/bmj/systreviews/default.asp References Overview: Egger M, Davey Smith G, Altman DG (eds) (2001) Systematic Reviews in Health Care: MetaAnalysis in Context London: BMJ Books Gough D, Oliver S, Thomas J (2012) An Introduction to Systematic Reviews SAGE Publications Ltd Pettricrew M, Roberts H (2006) Systematic Reviews in the Social Sciences: A Practical Guide Wiley-Blackwell Epidemiology in medicine Hennekens and BuringHarvard Medical School, Boston (1987) Khan K S, Kunz R, Kleijnen J, Antes G Systematic Reviews to support Evidence Based Medicine London: Hodder Arnold 2011 Shenkin SD et al Systematic reviews: guidance relevant for studies of older people Age and Ageing, 46(5): 722–728 https://doi.org/10.1093/ageing/afx105 Critical appraisal/risk of bias assessment: The pocket guide to critical appraisal Crombie BMJ Publishing Group, London (1996) ROBIS: A new tool to assess risk of bias in systematic reviews was developed Whiting et al 2016 Journal of Clinical Epidemiology 69: 225-234 http://www.sciencedirect.com/science/article/pii/S089543561500308X Testing a tool for assessing the risk of bias for nonrandomized studies showed moderate reliability and promising validity (ROBANS) Kim et al JCE 2013 http://dx.doi.org/10.1016/j.jclinepi.2012.09.016 http://www.jclinepi.com/article/S0895-4356(12)00322-8/abstract Harrison JK et al Using quality assessment tools to critically appraise ageing research: a guide for clinicians Age and Ageing 46(3): 359–365, https://doi.org/10.1093/ageing/afw223 Literature searching: Booth A ‘Unpacking your literature search toolbox: on search styles and tactics’ Health Information and Libraries Journal 2008; 25(4): 313-7 Cheng, K., C Preston, et al (1998) "Time to publication as full reports of abstracts of randomized controlled trials in cystic fibrosis." Pediatric Pulmonology 26(2): 101-105 Egger, M., P Juni, et al (2003) "How important are comprehensive literature searches and the assessment of trial quality in systematic reviews? Empirical study." Health Technology Assessment 7(1): 1-76 Hopewell S, McDonald S, Clarke MJ, Egger M Grey literature in meta-analyses of randomized trials of health care interventions Cochrane Database of Systematic Reviews 2007, Issue Art No.: MR000010 DOI: 10.1002/14651858.MR000010.pub3 Savoie, I., D Helmer, et al (2003) Beyond Medline: reducing bias through extended systematic review search International Journal of Technology Assessment in Health Care 19(1): 168-78 Meta-Analysis Borenstein M., Hedges L., Higgins J., Rothstein H (2009) Introduction to Meta-Analysis John Wiley & Sons Ltd Tierney J F., et al (2007) Practical methods for incorporating summary time-to-event data into meta-analysis Trials 2007, 8:16 http://handbook-5-1.cochrane.org/ https://www.meta-analysis.com/ http://www.metafor-project.org/ Contributors Susan Shenkin Clinical Senior Lecturer and Honorary Consultant in Geriatric Medicine School of Clinical Sciences and Community Health University of Edinburgh Medical School susan.shenkin@ed.ac.uk Mike Allerhand Statistician Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology University of Edinburgh michael.Allerhand@ed.ac.uk Anne Donnelly Academic Support Librarian (Philosophy, Psychology & Language Sciences) University of Edinburgh anne.donnelly@ed.ac.uk Rebecca Woodfield Postdoctoral Researcher and Specialty Registrar, Geriatric Medicine NHS Lothian Rebecca.Woodfield@nhslothian.scot.nhs.uk Ellen Backhouse PhD student Centre for Clinical Brain Sciences University of Edinburgh ellen.backhouse@ed.ac.uk .. .Resources Systematic Review Guidelines and Methodology Centre for Cognitive Ageing and Cognitive Epidemiology (CCACE: slides and resources from this course http://www .ccace. ed.ac.uk/research/software -resources/ systematic-reviewsand-meta-analyses... http://www .ccace. ed.ac.uk/research/software -resources/ systematic-reviewsand-meta-analyses Or http://tinyurl.com/sysrev1 Cochrane UK has a wealth of useful information, with focus on intervention studies... focus on evidence based policy and practice: http://www.campbellcollaboration.org /resources/ research/Methods_Links.php The Evidence for Policy and Practice Information and Co-ordinating Centre (EPPI-Centre)