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AMERICAN COLLEGE OF PHYSICIANS
CLERKSHIP DIRECTORS IN INTERNAL MEDICINE
AC P
INTERNAL MEDICINE
Essentials
for
Clerkship
Students
2
Patrick C. Alguire, MD, FACP
DIRECTOR
EDUCATION AND CAREER DEVELOPMENT
AMERICAN COLLEGE OF PHYSICIANS
EDITOR-IN-CHIEF
I
NTERNAL
M
EDICINE
Essentials
for
Clerkship
Students
2
Associate Publisher and Manager, Books Publishing: Tom Hartman
Production Supervisor: Allan S. Kleinberg
Senior Production Editor: Karen C. Nolan
Editorial Coordinator: Angela Gabella
Design: Michael E. Ripca
Copyright © 2009 by the American College of Physicians. All rights reserved. No part of
this publication may be reproduced in any form by any means (electronic, mechanical,
xerographic, or other) or held in any information storage or retrieval systems without
written permission from the College.
Printed in the United States of America
Printed by Sheridan Books
Composition by Scribe, Inc. (www.scribenet.com)
ISBN: 978-1-934465-13-4
The authors and publisher have exerted every effort to ensure that the drug selection
and dosages set forth in this book are in accordance with current recommendations and
practice at the time of publication. In view of ongoing research, occasional changes in
government regulations, and the constant flow of information relating to drug therapy
and drug reactions, however, the reader is urged to check the package insert for each
drug for any change in indications and dosage and for added warnings and precautions.
This care is particularly important when the recommended agent is a new or infrequently
used drug.
0910111213 / 10987654321
Section Editors
Thomas M. DeFer, MD, FACP
Clerkship Director
Division of Medical Education
Department of Internal Medicine
Washington University School of Medicine
St Louis, Missouri
D. Michael Elnicki, MD, FACP
Director, Ambulatory Medicine Clerkship
Director, Section of General Internal Medicine
University of Pittsburgh School of Medicine
UPMC Shadyside
Pittsburgh, Pennsylvania
Mark J. Fagan, MD
Clerkship Director
Department of Medicine
Alpert Medical School of Brown University
Providence, Rhode Island
Sara B. Fazio, MD
Assistant Professor, Harvard Medical School
Director, Core I Medicine Clerkship
Division of General Internal Medicine
Beth Israel Deaconess Medical Center
Boston, Massachusetts
James L. Sebastian, MD, FACP
Director of Student Teaching Programs
Department of Medicine
Medical College of Wisconsin
Clement J. Zablocki Veterans Affairs Medical Center
Milwaukee, Wisconsin
v
Arlina Ahluwalia, MD
Clinical Assistant Professor of Medicine
Stanford University School of Medicine
Clerkship Site Director
Palo Alto VAHCS
Palo Alto, California
Eyad Al-Hihi, MD, FACP
Associate Professor of Medicine
Clerkship Director, Ambulatory Medicine
Section Chief, Division of General Internal Medicine
Medical Director, Internal Medicine Clinics
Truman Medical Center-Hospital Hill
University of Missouri-Kansas City School of
Medicine
Kansas City, Missouri
Erik K. Alexander, MD, FACP
Director, Medical Student Education
Brigham & Women’s Hospital
Assistant Professor of Medicine
Harvard Medical School
Boston, Massachusetts
Irene Alexandraki, MD, FACP
Assistant Professor of Medicine
University of Florida College of Medicine
Jacksonville, Florida
Mark R. Allee, MD, FACP
Assistant Professor of Medicine
Department of Internal Medicine
University of Oklahoma College of Medicine
Oklahoma City, Oklahoma
Hugo A. Alvarez, MD, FACP
Associate Professor of Medicine
Sub-Internship Director
Clerkship Site Director, Department of Medicine
Rosalind Franklin University of Medicine and Science
Mount Sinai Hospital
Chicago, Illinois
Alpesh N. Amin, MD, MBA, FACP
Medicine Clerkship Director
Associate Program Director, IM Residency
University of California, Irvine
Irvine, California
Mary Jane Barchman, MD, FACP, FASN
Associate Professor of Medicine
Section of Nephrology and Hypertension
Director, Introduction to Medicine Course
Clerkship Director, Internal Medicine
Brody School of Medicine at East Carolina University
Greenville, North Carolina
Seth Mark Berney, MD, FACP
Professor of Medicine
Chief, Section of Rheumatology
Director, Center of Excellence for Arthritis and
Rheumatology
Health Sciences Center
Louisiana State University School of Medicine
Shreveport, Louisiana
Contributors
Cynthia A. Burns, MD
Assistant Professor
Clerkship Director, Inpatient Internal Medicine
Section of Endocrinology and Metabolism
Department of Internal Medicine
Wake Forest University School of Medicine
Winston-Salem, North Carolina
Amanda Cooper, MD
Assistant Professor of Medicine
University of Pittsburgh School of Medicine
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania
Nicole M. Cotter, MD
Fellow, Section of Rheumatology
Center of Excellence for Arthritis and Rheumatology
Health Sciences Center
Louisiana State University School of Medicine
Shreveport, Louisiana
Reed E. Drews, MD, FACP
Program Director
Hematology-Oncology Fellowship
Co-Director, Core Medicine 1 Clerkship
Beth Israel Deaconess Medical Center
Harvard Medical School
Boston, Massachusetts
Steven J. Durning, MD, FACP
Major, Medical Corps, US Air Force
Associate Professor of Medicine
Co-Director, Intro to Clinical Reasoning Course
Uniformed Services University of the Health Sciences
Bethesda, Maryland
Richard S. Eisenstaedt, MD, FACP
Chair, Department of Medicine
Abington Memorial Hospital
Professor of Medicine
Temple University School of Medicine
Philadelphia, Pennsylvania
J. Michael Finley, DO, FACP, FACOI
Associate Professor and Chair of Medicine
Department of Medicine
Western University College of Osteopathic Medicine
Pomona, California
Janine M. Frank, MD
Assistant Professor of Medicine
University of Pittsburgh Medical Center
University of Pittsburgh School of Medicine
Pittsburgh, Pennsylvania
Jane P. Gagliardi, MD
Assistant Clinical Professor
Department of Internal Medicine
Department of Psychiatry and Behavioral Sciences
Duke University School of Medicine
Durham, North Carolina
Peter Gliatto, MD
Assistant Professor of Medicine
Director, Medical Clerkships
Mount Sinai School of Medicine
New York, New York
Eric H. Green, MD, MSc
Course Director, Patients, Doctors, and Communities
Assistant Professor of Medicine
Montefiore Medical Center
Albert Einstein College of Medicine
Bronx, New York
Mark C. Haigney, MD
Professor of Medicine
Director of Cardiology
Uniformed Services University of the Health Sciences
Bethesda, Maryland
Charin L. Hanlon, MD, FACP
Assistant Professor of Internal Medicine
Clerkship Director, Internal Medicine
West Virginia University-Charleston Division
Charleston, West Virginia
Warren Y. Hershman, MD
Director of Student Education
Department of Medicine
Boston University School of Medicine
Boston, Massachusetts
Mark D. Holden, MD, FACP
Eagle’s Trace Medical Director
Erickson Retirement Communities
Houston, Texas
vi • Contributors
Ivonne Z. Jiménez-Velázquez, MD, FACP
Professor and Vice-Chair for Education
Geriatrics Program Director
Clerkship Director, Internal Medicine Department
University of Puerto Rico School of Medicine
San Juan, Puerto Rico
Lawrence I. Kaplan, MD, FACP
Professor of Medicine
Section Chief, General Internal Medicine
Internal Medicine Clerkship Director
Temple University School of Medicine
Philadelphia, Pennsylvania
Asra R. Khan, MD
Assistant Professor of Clinical Medicine
Associate Program Director, Internal Medicine
Residency
Medicine Clerkship Director
University of Illinois College of Medicine
Chicago, Illinois
Sarang Kim, MD
Assistant Professor of Medicine
Division of General Internal Medicine
University of Medicine and Dentistry of New Jersey
Robert Wood Johnson Medical School
New Brunswick, New Jersey
Christopher A. Klipstein, MD
Clerkship Director of Internal Medicine
Associate Professor
Department of Medicine
University of North Carolina School of Medicine
Chapel Hill, North Carolina
Cynthia H. Ledford, MD
Clerkship Director of Internal Medicine
Ohio State University College of Medicine
Columbus, Ohio
Bruce Leff, MD, FACP
Associate Professor of Medicine
Medicine Clerkship Director
Johns Hopkins University School of Medicine
Baltimore, Maryland
Fred A. Lopez, MD, FACP
Associate Professor and Vice Chair
Department of Medicine
Louisiana State University Health Sciences Center
Assistant Dean for Student Affairs
LSU School of Medicine
New Orleans, Louisiana
Anna C. Maio, MD, FACP
Division Chief and Associate Professor
Division of General Internal Medicine
Department of Internal Medicine
Creighton University School of Medicine
Omaha, Nebraska
Brown J. McCallum, MD, FACP
Assistant Professor
Co-Clerkship Director
Department of Internal Medicine
University of South Carolina School of Medicine
Columbia, South Carolina
Kevin M. McKown, MD, FACP
Associate Professor of Medicine
Co-Chief, Section of Rheumatology
Program Director, Rheumatology Fellowship
Co-Clerkship Director
Department of Medicine
University of Wisconsin School of Medicine and
Public Health
Madison, Wisconsin
Melissa A. McNeil, MD, MPH
Professor of Medicine and Obstetrics, Gynecology &
Reproductive Sciences
Chief, Section of Women’s Health
Division of General Medicine
University of Pittsburgh
Pittsburgh, Pennsylvania
Janet N. Myers, MD, FACP, FCCP
Associate Professor of Medicine
Deputy Clerkship Director, Department of Medicine
Uniformed Services University of the Health Sciences
Bethesda, Maryland
Contributors • vii
Kathryn A. Naus, MD
Chief Fellow, Section of Rheumatology
Center of Excellence for Arthritis and Rheumatology
Health Sciences Center
Louisiana State University School of Medicine
Shreveport, Louisiana
Robert W. Neilson Jr., MD
Assistant Professor
Clerkship Director
Department of Internal Medicine
Division of General Internal Medicine
Texas Tech University Health Sciences Center
Lubbock, Texas
Katherine Nickerson, MD
Vice Chair
Department of Medicine
Associate Professor of Clinical Medicine
Clerkship Director
Columbia University, P & S
New York, New York
L. James Nixon, MD
Clerkship Director
Division of General Internal Medicine
University of Minnesota Medical School
University of Minnesota Medical Center, Fairview
Minneapolis, Minnesota
Carlos Palacio, MD, MPH, FACP
Clerkship Director
Assistant Professor of Medicine
University of Florida College of Medicine
Jacksonville, Florida
Hanah Polotsky, MD
Assistant Professor of Medicine
Clerkship Director
Montefiore Medical Center
Albert Einstein College of Medicine
Bronx, New York
Nora L. Porter, MD
Co-Director, Internal Medicine Clerkship
St. Louis University School of Medicine
St. Louis, Missouri
Priya Radhakrishnan, MD
Clinical Assistant Professor
University of Arizona College of Medicine
Clerkship Director and Associate Program Director
Department of Internal Medicine
St. Joseph Hospital & Medical Center
Phoenix, Arizona
Joseph Rencic, MD, FACP
Assistant Professor of Medicine
Clerkship Site Director, Associate Program Director
Department of Internal Medicine
Tufts-New England Medical Center
Boston, Massachusetts
Kathleen F. Ryan, MD
Associate Professor of Medicine
Clerkship Director
Division of General Internal Medicine
Department of Internal Medicine
Drexel University College of Medicine
Philadelphia, Pennsylvania
Brijen J. Shah, MD
Chief Medical Resident, Department of Medicine
Beth Israel Deaconess Medical Center
Harvard Medical School
Boston, Massachusetts
Patricia Short, MD
Major, Medical Corps, US Army
Associate Professor and Associate Clerkship Director
Department of Medicine
Uniformed Services University of the Health Sciences
Bethesda, Maryland
Madigan Army Medical Center
Tacoma, Washington
Diane C. Sliwka, MD
Instructor of Medicine
Beth Israel Deaconess Medical Center
Harvard Medical School
Boston, Massachusetts
viii • Contributors
Harold M. Szerlip, MD, FACP, FCCP
Professor and Vice-Chairman
Department of Medicine
Medical College of Georgia
Augusta, Georgia
Gary Tabas, MD, FACP
Associate Professor of Medicine
University of Pittsburgh School of Medicine
Pittsburgh, Pennsylvania
Tomoko Tanabe, MD, FACP
Assistant Professor of Medicine
Associate Clerkship Director
University of California, San Diego
San Diego, California
David C. Tompkins, MD
Associate Chair
Department of Medicine
SUNY Stony Brook Health Sciences Center
Stony Brook, New York
Dario M. Torre, MD, MPH, FACP
Clerkship Director
Department of Medicine
Medical College of Wisconsin
Milwaukee, Wisconsin
Mark M. Udden, MD, FACP
Professor of Medicine
Department of Internal Medicine
Baylor College of Medicine
Houston, Texas
H. Douglas Walden, MD, MPH, FACP
Co-Director, Internal Medicine Clerkship
St. Louis University School of Medicine
St. Louis, Missouri
Joseph T. Wayne, MD, MPH, FACP
Associate Professor of Medicine
Associate Professor of Pediatrics
Clerkship Director, Internal Medicine
Albany Medical College
Albany, New York
John Jason White, MD
Assistant Professor of Medicine
Nephrology Section
Department of Medicine
Medical College of Georgia
Augusta, Georgia
Kevin D. Whittle, MD
Assistant Professor
Third Year Clerkship Director, Internal Medicine
Sanford Medical School of the University of South
Dakota
Sioux Falls, South Dakota
Contributors • ix
xi
FOREWORD xv
A
CKNOWLEDGMENTS xvii
I Cardiovascular Medicine
1 Approach to Chest Pain 3
Dario M. Torre
2 Chronic Stable Angina 7
Anna C. Maio
3 Acute Coronary Syndrome 11
Patrick C. Alguire
4 Supraventricular Arrhythmias 15
Charin L. Hanlon
5 Ventricular Arrhythmias 20
Steven J. Durning and Mark C. Haigney
6 Heart Failure 24
James L. Sebastian
7 Valvular Heart Disease 28
H. Douglas Walden
II Endocrinology and Metabolism
8 Diabetes Mellitus and Diabetic Ketoacidosis 37
Erik K. Alexander
9 Dyslipidemia 41
D. Michael Elnicki and Gary Tabas
10 Thryoid Disease 44
Erik K. Alexander
11 Adrenal Disease 48
Cynthia A. Burns
12 Osteoporosis 52
Melissa A. McNeil and Janine M. Frank
III Gastroenterology and Hepatology
13 Approach to Abdominal Pain 57
Priya Radhakrishnan
14 Approach to Diarrhea 61
Sarang Kim
15 Diseases of the Gallbladder and Bile Ducts 64
Nora L. Porter
16 Acute Pancreatitis 67
Nora L. Porter
17 Gastroesophageal Reflux Disease 70
Brown J. McCallum
18 Peptic Ulcer Disease 72
Brown J. McCallum
19 Dyspepsia 74
Brown J. McCallum
20 Approach to Gastrointestinal Bleeding 76
Warren Y. Hershman
21 Viral Hepatitis 80
Carlos Palacio
22 Cirrhosis 83
Mark J. Fagan
23 Inflammatory Bowel Disease 87
Brown J. McCallum
IV General Internal Medicine
24 Test Interpretation 93
D. Michael Elnicki
25 Health Promotion, Screening, and Prevention 96
L. James Nixon
26 Approach to Syncope 100
Lawrence I. Kaplan
Contents
[...]... Society for General Internal Medicine A collaboration of 66 authors, all of whom are either internal medicine clerkship directors or clerkship faculty, representing 45 different medical schools, IM Essentials 2 is unique in that it is created by faculty who helped design the internal medicine curriculum and who are actively involved in teaching and advising students on the internal medicine clerkship. .. Cancer 26 2 Eric H Green 71 Cervical Cancer 26 5 Asra R Khan 72 Skin Cancer 26 8 Cynthia H Ledford 73 Pain Management 27 1 Patrick C Alguire X Pulmonary Medicine 74 Approach to Dyspnea 27 5 Mark D Holden 75 Pleural Effusion 27 8 Dario M Torre 76 Asthma 28 2 Patricia Short 77 Chronic Obstructive Pulmonary Disease 28 6 Carlos Palacio 78 Obstructive Sleep Apnea 29 0 Arlina... the internal medicine clerkship I nternal Medicine Essentials for Clerkship Students is a collaborative project of the American College of Physicians (ACP) and the Clerkship Directors in Internal Medicine (CDIM), the organization of individuals responsible for teaching internal medicine to medical students The purpose of IM Essentials is to provide medical students with an authoritative educational... The Clerkship Directors in Internal Medicine is the national organization of individuals responsible for teaching internal medicine to medical students Founded in 1989, CDIM promotes excellence in the education of medical students in internal medicine CDIM serves internal medicine faculty and staff by: providing a forum to share ideas, generate solutions to common problems, and create opportunities for. .. of the Clerkship Directors in Internal Medicine and the Education Committee and the Council of Student Members of the American College of Physicians Patrick C Alguire, MD, FACP Editor-in-Chief Acknowledgments The American College of Physicians and the Clerkship Directors in Internal Medicine gratefully acknowledge the special contributions to Internal Medicine Essentials for Clerkship Students 2 of Nicole... 7-9 in the Cardiovascular Medicine section Bibliography American College of Physicians Medical Knowledge Self-Assessment Program 14 Philadelphia: American College of Physicians; 20 06 Klompas M Does this patient have an acute thoracic aortic dissection? JAMA 20 02; 287 :22 62- 72 [PMID: 11980 527 ] Lee TH, Goldman L Evaluation of the patient with acute chest pain N Engl J Med 20 00;3 42: 1187-95 [PMID: 10770985]... bibliography We recommend that students first read the appropriate chapter in IM Essentials, then assess their understanding by answering the designated questions in MKSAP for Students 4 The content of IM Essentials is based upon The Core Medicine Clerkship Curriculum Guide (available at www.im.org/CDIM), a nationally recognized curriculum for the required third-year internal medicine clerkship, created and... 62 Headache 23 4 Eyad Al-Hihi 63 Dementia 23 7 Mark Allee 64 Approach to Meningitis and Encephalitis 24 0 Fred A Lopez 65 Stroke and Transient Ischemic Attack 24 4 Jane P Gagliardi 66 Peripheral Neuropathy 24 7 Christopher A Klipstein IX Oncology 67 Breast Cancer 25 3 Kathleen F Ryan 68 Colon Cancer 25 6 Kathleen F Ryan Contents • xiii 69 Lung Cancer 25 9 Cynthia H Ledford... 20 0 Fred A Lopez 55 Osteomyelitis 20 3 David C Tompkins VII Nephrology 56 Acute Kidney Injury 20 9 Harold M Szerlip 57 Chronic Kidney Disease 21 3 John Jason White 58 Acid-Base Disorders 21 7 Tomoko Tanabe 59 Fluid and Electrolyte Disorders 22 0 Mary Jane Barchman 60 Calcium and Phosphorus Metabolism 22 5 Mary Jane Barchman VIII Neurology 61 Approach to the Altered Mental State 23 1... electrocardiography interpretation In MKSAP for Students 4, assess yourself with items 23 29 in the Cardiovascular Medicine section Bibliography Delacrétaz E Clinical practice Supraventricular tachycardia N Engl J Med 20 06;354:1039-51 [PMID: 16 525 141] Ferrari VA, Callans D, Wiegers S Atrial Fibrillation http://pier.acponline org/physicians/diseases/d 027 [Date accessed: 20 08 Jan 23 ] In: PIER [online database] Philadelphia: . AMERICAN COLLEGE OF PHYSICIANS
CLERKSHIP DIRECTORS IN INTERNAL MEDICINE
AC P
INTERNAL MEDICINE
Essentials
for
Clerkship
Students
2
Patrick C. Alguire, MD, FACP
DIRECTOR
EDUCATION. contributions to Internal Medicine
Essentials for Clerkship Students 2 of Nicole V. Baptista, CDIM Policy
Coordinator, Clerkship Directors in Internal Medicine; Sheila
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