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Preprocessing EEG & MEG final

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Pre-processing for EEG and MEG Przemek Tomalski & Kathrin Cohen Kadosh Recording EEG QuickTime™ and a TIFF (Uncompressed) decompressor are needed to see this picture. Two crucial steps  Activity caused by your stimulus (ERP) is ‘hidden’ within continuous EEG stream  ERP is your ‘signal’, all else in EEG is ‘noise’  Event-related activity should not be random, we assume all else is  Epoching – cutting the data into chunks referenced to stimulus presentation  Averaging – calculating the mean value for each time-point across all epochs Extracting ERP from EEG ERPs emerge from EEG as you average trials together Overview Pre-processing  Converting the data  Epoching/Segmentation  Filtering  Artifact Detection/Rejection  Averaging  Re-referencing Convert the data [...]... needed to see this picture Filtering in SPM Overview Pre-processing       Converting the data Epoching/Segmentation Filtering Artifact Detection/Rejection Averaging Re-referencing Artifacts in EEG signal Blinks Eye-movements Muscle activity EKG Skin potentials Alpha waves Eye blinks QuickTime™ and a TIFF (Uncompressed) decompressor are needed to see this picture Eye movements QuickTime™ and... the square root of the number of trials As a general rule, it’s always better to try to decrease sources of noise than to increase the number of trials Averaging Averaging    Assumes that only the EEG noise varies from trial to trial But – amplitude and latency will vary Variable latency is usually a bigger problem than variable amplitude Averaging: effects of variance Latency variation can be a . Pre-processing for EEG and MEG Przemek Tomalski & Kathrin Cohen Kadosh Recording EEG QuickTime™ and a TIFF (Uncompressed) decompressor are. by your stimulus (ERP) is ‘hidden’ within continuous EEG stream  ERP is your ‘signal’, all else in EEG is ‘noise’  Event-related activity should not be

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