[...]... [13-18], and noncovalent bond cross-linking [1921] The block copolymers are molecularly converted in situ from the nonamphiphilic copolymers completely dissolved in a solvent to amphiphilic copolymers due to these stimuli Therefore, the association and dissociation of the isolated copolymers are reversibly controlled by such stimuli The induced self-assembly has advantages over direct self-assembly of amphiphilic. .. onto the polymer by the way of immobilization of the chiral ligand Different types of ligand immobilization are presented: pendant ligands anchored on a polymer prepared by a polymer reaction, ligands on the backbone prepared by copolymerization and molecular imprinting technique Examples of their use, performance and recyclability in a variety of enantioselective reactions such as alkylation and reductions... over direct self-assembly of amphiphilic copolymers in molecular designing There is no dependence on the balance of solvophilic and solvophobic moieties when designing the copolymers Thus, a better selection of the driving force can be provided The advantages also include the fact that a variety of amphiphilic copolymers can be created from one nonamphiphilic copolymer in situ by selecting the stimuli... block copolymers to modulate multi drug resistance related processes has been demonstrated the first time more than 10 years ago Nowadays, the efflux pump inhibitory activity of amphiphilic block copolymers is used in two main areas First, to improve the transport of efflux pump substrates across the blood brain barrier (BBB) and second, in cancer therapy It has been shown that in the presence of amphiphilic. .. nitroxides is a precise tool for marking heterogeneous oxidation of polyolefins In: Polymer Aging, Stabilizers and Amphiphilic Editors: L Segewicz, M Petrowsky, pp 1-28 ISBN: 978-1-60692-928-5 © 2010 Nova Science Publishers, Inc Chapter 1 RESEARCH AND REVIEW AND STUDIES INDUCED SELF-ASSEMBLY OF DIBLOCK COPOLYMERS Eri Yoshida Department of Materials Science, Toyohashi University of Technology, Hibarigaoka,... features, coming from their block copolymer structure and their ability to be stimuli responsive, establishes this class of copolymers as a core of intense research interest, aiming at elucidating aspects regarding their targeted synthesis, solution behavior and application possibilities In this chapter, the current developments in the field of double hydrophilic block copolymers are discussed In particular,... presence of amphiphilic block copolymers higher concentrations of certain anticancer drugs, which are xii Liudvikas Segewicz and Marijus Petrowsky known as efflux pump substrates, can be found in the brain Within the current chapter, recent developments in the field of amphiphilic block copolymer mediated efflux pump inhibition are discussed Besides presenting data from in vitro and vivo studies, also... mechanisms and the molecular selfassembly in vivo has been clarified, control of the self-assembly by electron transport has been applied for an artificial polymeric surfactant Figure 1-1-1 Redox system of TEMPO 2 Eri Yoshida Figure 1-1-2 The PVTEMPO-b-PSt diblock copolymer 1.1 Oxidation-Induced Micellization Oxidation-induced micellization of a diblock copolymer was determined for a diblock copolymer... poly(4-vinylbenzyloxy-TEMPO )block- polystyrene (PVTEMPO-b-PSt) diblock copolymer obtained by the reaction of 4hydroxy-TEMPO and PVBC-b-PSt (Figure 1-1-2) The molecular weight of copolymer was Mn(PVTEMPO-b-PSt) = 31,200-b-49,400 The PVTEMPO-b-PSt diblock copolymer showed no self-assembly in carbon tetrachloride, a nonselective solvent Dynamic light scattering demonstrated that the copolymer self-assembled... consumed by 1.94 equivalents of the chlorine and only 3% of the TEMPO remained unreacted Figure 1-1-6 Variation in the UV absorbance of the PVTEMPO-b-PSt copolymer during the micellization The chlorine to the VTEMPO unit was 0, 0.13, 0.28, 0.58, 1.11, and 1.94 equivalents from the bottom Research and Review and Studies Induced Self-Assembly of Diblock Copolymers 5 Figure 1-1-7 The variation in UV absorbance . x0 y0 w0 h1" alt="" POLYMER SCIENCE AND TECHNOLOGY SERIES POLYMER AGING, STABILIZERS AND AMPHIPHILIC BLOCK COPOLYMERS No part. Modena and Bice Conti 2010. ISBN: 978-1-61668-892-9 (Online Book) Polymer Aging, Stabilizers and Amphiphilic Block Copolymers Liudvikas Segewicz and