Tài liệu Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 50) ppt

... method was about 1 µg/mL in blood plasma. Poisoning case, and toxic and fatal concentrations A 20-year-old male [2] attempted suicide by ingesting a large amount of a nonfreezing coolant at about ... is being used as a component of cold-reserving materials and of nonfreezing coolants of automobiles.  ere were cases of accidental and suicidal ingestion of such...

Ngày tải lên: 22/01/2014, 00:20

... MO, USA). Pure powder of perazine and clospi- razine was donated by Mitsubishi Welpharma, Osaka, Japan; that of  upentixol by Takeda Chem. Ind. Ltd., Osaka, Japan; that of thioproperazine by ... Springer-Verlag Berlin Heidelberg 2005 II.3.1 Phenothiazines by Akira Ishii and Yoshinao Katsumata Introduction Phenothiazine drugs, including chlorpromazine and levomepromazine, have...

Ngày tải lên: 15/12/2013, 12:15

... timiperone and spiperone with relatively high molecular weights, LC/MS may be most suitable. Poisoning cases, and toxic and fatal concentrations A 2-year plus 5 month-old female and an 11-month-old male ... dyskinesia of the face, appeared.  us, diphenhydramine was injected into her intravenously; she recov- ered 4 days a er admission. For the male baby, similar treatments, suc...

Ngày tải lên: 15/12/2013, 12:15

... antidepressants and carbamazepine obtained by HPLC-UV. A: carbamazepine, B: desipramine, C: maprotiline, D: nortriptyline, E: amoxapine, F: setiptiline, G: mianserin, H: imipramine, I: amitriptyline, ... 52:1190–1195 (in Japanese) 3) Tanaka E, Terada M, Nakamura T et al. (1997) Forensic analysis of eleven cyclic antidepressants in human biolo- gical samples using a new reverse...

Ngày tải lên: 15/12/2013, 12:15

... Tanaka E, Nakamura T, Nagashima A et al. (2001) Determination of plasma bromvalerylurea and its main meta- bolite by a simple high-performance liquid chromatographic method and quantitation of ... screening of drugs in biological materials by gas chromatography and gas chromatography-mass spectrometry. A fatal poisoning by ingestion of a drug containing acetaminophe...

Ngày tải lên: 15/12/2013, 12:15

... barbiturate Case 1 [27]: a 40–45 year-old (estimated) female was found dead on a bed of a hotel. In her room, 2 tablets of Vegetamin (a combined drug containing, phenobarbital, promethazine and ... GC and HPLC are presented. Incidence of fatal barbiturate poisoning cases. Since fatal cases due to Vegetamin® tablets containing phenobarbital are many, its incidence rate is...

Ngày tải lên: 15/12/2013, 12:15

... phenytoin and carbamazepine- epoxide can be purchased from Sigma. Lamotrigine, carbamazepine-diol and 9-hydroxy- methyl-10-carbamyl acridan were reported to be obtainable from Chiba-Geigy (Basel, ... preparation • Carbamazepine, ethosuximide, phenytoin, primidone, phenobarbital, diazepam, oxaze- pam, nitrazepam and 5-( 4-methylphenyl )-5 -phenylhydantoin (internal standard, IS) can...

Ngày tải lên: 15/12/2013, 12:15

... uoroacetic acid can be added to a mobile phase as an ion-pairing reagent for analysis of the quaternary amino muscle relaxants [6]. e) For solid-phase extraction of the drugs, weak cation-exchanger ... Dragendorff reagent; ➄ : iodoplatinate reagent TLC analysis 362 Muscle relaxants Direct inlet MS analysis [4] Reagents and their preparation • A 1-g aliquot of iodine and...

Ngày tải lên: 24/12/2013, 18:15

... β-receptors; they cause hypotension by decreasing the heart beat rate and cardiac output, and prevent the attacks of arrhythmia and angina pectoris. In the brain, the drugs attenuate migraine ... e β-blockers are structurally classi ed into isopropylamino drugs such as propranolol and tertiary butylamino drugs such as nadolol; and many products containing 26 kinds of β...

Ngày tải lên: 24/12/2013, 18:15

... for bleaching and other purposes. Sodium hypochlorite ( NaClO) aqueous solu- tion is usually used as a disinfectant, bleaching agent, fungicide and ink eraser, and is thus usually included in detergents ... solutions are analyzed by the above CE to construct a calibration curve (concentration of a hypochlorite ion in a specimen vs. peak area). A peak area obtained fro...

Ngày tải lên: 24/12/2013, 18:15